Low-resolution solution structures of Munc18:Syntaxin protein complexes indicate an open binding mode driven by the Syntaxin N-peptide

Resolving the Function of Distinct Munc18-1/SNARE Protein Interaction Modes in a Reconstituted Membrane Fusion Assay

(2011) Yvette Schollmeier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dual roles of Munc18-1 rely on distinct binding modes of the central cavity with Stx1A and SNARE complex

(2011) Lei Shi et al.   MOLECULAR BIOLOGY OF THE CELL

Munc18-1 domain-1 controls vesicle docking and secretion by interacting with syntaxin-1 and chaperoning it to the plasma membrane

(2011) Gayoung A. Han et al.   MOLECULAR BIOLOGY OF THE CELL

Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings

(2011) Natacha Rochel et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Munc13 mediates the transition from the closed syntaxin–Munc18 complex to the SNARE complex

(2011) Cong Ma et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Primordial neurosecretory apparatus identified in the choanoflagellate Monosiga brevicollis

(2011) P. Burkhardt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-Vesicle Fusion Assay Reveals Munc18-1 Binding to the SNARE Core Is Sufficient for Stimulating Membrane Fusion

(2010) Jiajie Diao et al.   ACS Chemical Neuroscience

SNARE bundle and syntaxin N-peptide constitute a minimal complement for Munc18-1 activation of membrane fusion

(2010) Jingshi Shen et al.   JOURNAL OF CELL BIOLOGY

Syntaxin N-terminal peptide motif is an initiation factor for the assembly of the SNARE-Sec1/Munc18 membrane fusion complex

(2010) S. S. Rathore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Possible roles for Munc18-1 domain 3a and Syntaxin1 N-peptide and C-terminal anchor in SNARE complex formation

(2010) S.-H. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Abrogating Munc18-1-SNARE Complex Interaction Has Limited Impact on Exocytosis in PC12 Cells

(2009) Nancy T. Malintan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Munc18-1 binding to the neuronal SNARE complex controls synaptic vesicle priming

(2009) Ferenc Deák et al.   JOURNAL OF CELL BIOLOGY

Rescue of Munc18-1 and -2 Double Knockdown Reveals the Essential Functions of Interaction between Munc18 and Closed Syntaxin in PC12 Cells

(2009) Liping Han et al.   MOLECULAR BIOLOGY OF THE CELL

Binding of UNC-18 to the N-terminus of syntaxin is essential for neurotransmission inCaenorhabditis elegans

(2008) James R. Johnson et al.   BIOCHEMICAL JOURNAL

Binding of the Munc13-1 MUN Domain to Membrane-Anchored SNARE Complexes†

(2008) Rong Guan et al.   BIOCHEMISTRY

Munc18a controls SNARE assembly through its interaction with the syntaxin N-peptide

(2008) Pawel Burkhardt et al.   EMBO JOURNAL

MULCh: modules for the analysis of small-angle neutron contrast variation data from biomolecular assemblies

(2008) Andrew E. Whitten et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

NMR analysis of the closed conformation of syntaxin-1

(2008) Xiaocheng Chen et al.   JOURNAL OF BIOMOLECULAR NMR

UNC-18 Promotes Both the Anterograde Trafficking and Synaptic Function of Syntaxin

(2008) Jason M. McEwen et al.   MOLECULAR BIOLOGY OF THE CELL

Munc18a Scaffolds SNARE Assembly to Promote Membrane Fusion

(2008) Travis L. Rodkey et al.   MOLECULAR BIOLOGY OF THE CELL

Synaptic vesicle fusion

(2008) Josep Rizo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Accessory Proteins Stabilize the Acceptor Complex for Synaptobrevin, the 1:1 Syntaxin/SNAP-25 Complex

(2008) Keith Weninger et al.   STRUCTURE

Munc18-1 Is Critical for Plasma Membrane Localization of Syntaxin1 but Not of SNAP-25 in PC12 Cells

(2007) Lakshmanan Arunachalam et al.   MOLECULAR BIOLOGY OF THE CELL