DNA cleavage and opening reactions of human topoisomerase II  are regulated via Mg2+-mediated dynamic bending of gate-DNA

Use of divalent metal ions in the DNA cleavage reaction of topoisomerase IV

(2011) S. L. Pitts et al.   NUCLEIC ACIDS RESEARCH

Direct measurement of DNA bending by type IIA topoisomerases: implications for non-equilibrium topology simplification

(2011) Ashley H. Hardin et al.   NUCLEIC ACIDS RESEARCH

Protein induced fluorescence enhancement as a single molecule assay with short distance sensitivity

(2011) H. Hwang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA-induced narrowing of the gyrase N-gate coordinates T-segment capture and strand passage

(2011) A. Gubaev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis of Type II Topoisomerase Inhibition by the Anticancer Drug Etoposide

(2011) C.-C. Wu et al.   SCIENCE

Origins of Specificity in Protein-DNA Recognition

(2010) Remo Rohs et al.   Annual Review of Biochemistry

Cellular Strategies for Regulating DNA Supercoiling: A Single-Molecule Perspective

(2010) Daniel A. Koster et al.   CELL

DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs

(2010) Yves Pommier et al.   CHEMISTRY & BIOLOGY

The use of divalent metal ions by type II topoisomerases

(2010) Joseph E. Deweese et al.   Metallomics

A novel and unified two-metal mechanism for DNA cleavage by type II and IA topoisomerases

(2010) Bryan H. Schmidt et al.   NATURE

Type IIA topoisomerase inhibition by a new class of antibacterial agents

(2010) Benjamin D. Bax et al.   NATURE

Structural Basis of Gate-DNA Breakage and Resealing by Type II Topoisomerases

(2010) Ivan Laponogov et al.   PLoS One

Coordinating the Two Protomer Active Sites of Human Topoisomerase IIα: Nicks as Topoisomerase II Poisons†

(2009) Joseph E. Deweese et al.   BIOCHEMISTRY

Structural insight into the quinolone–DNA cleavage complex of type IIA topoisomerases

(2009) Ivan Laponogov et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Effects of magnesium and related divalent metal ions in topoisomerase structure and function

(2009) C. Sissi et al.   NUCLEIC ACIDS RESEARCH

The DNA-gate of Bacillus subtilis gyrase is predominantly in the closed conformation during the DNA supercoiling reaction

(2009) A. Gubaev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Using 3′-Bridging Phosphorothiolates To Isolate the Forward DNA Cleavage Reaction of Human Topoisomerase IIα†

(2008) Joseph E. Deweese et al.   BIOCHEMISTRY

Coupling between ATP Binding and DNA Cleavage by DNA Topoisomerase II

(2008) Felix Mueller-Planitz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A practical guide to single-molecule FRET

(2008) Rahul Roy et al.   NATURE METHODS

Human topoisomerase II  uses a two-metal-ion mechanism for DNA cleavage

(2008) J. E. Deweese et al.   NUCLEIC ACIDS RESEARCH

The DNA cleavage reaction of topoisomerase II: wolf in sheep's clothing

(2008) J. E. Deweese et al.   NUCLEIC ACIDS RESEARCH

DNA topoisomerases: harnessing and constraining energy to govern chromosome topology

(2008) Allyn J. Schoeffler et al.   QUARTERLY REVIEWS OF BIOPHYSICS