The role of butyrate, a histone deacetylase inhibitor in diabetes mellitus: experimental evidence for therapeutic intervention
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Title
The role of butyrate, a histone deacetylase inhibitor in diabetes mellitus: experimental evidence for therapeutic intervention
Authors
Keywords
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Journal
Epigenomics
Volume 7, Issue 4, Pages 669-680
Publisher
Future Medicine Ltd
Online
2015-06-26
DOI
10.2217/epi.15.20
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Note: Only part of the references are listed.- Valproate attenuates the proteinuria, podocyte and renal injury by facilitating autophagy and inactivation of NF-κB/iNOS signaling in diabetic rat
- (2015) Sabbir Khan et al. BIOCHIMIE
- Sodium valproate ameliorates diabetes-induced fibrosis and renal damage by the inhibition of histone deacetylases in diabetic rat
- (2015) Sabbir Khan et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Protective role of sodium butyrate, a HDAC inhibitor on beta-cell proliferation, function and glucose homeostasis through modulation of p38/ERK MAPK and apoptotic pathways: Study in juvenile diabetic rat
- (2014) S. Khan et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Minor association of kinase insert domain-containing receptor gene polymorphism (rs2071559) with myocardial infarction in Caucasians with type 2 diabetes mellitus: Case–control cross-sectional study
- (2014) Stojan Kariž et al. CLINICAL BIOCHEMISTRY
- Aberrant gut microbiota composition at the onset of type 1 diabetes in young children
- (2014) Marcus C. de Goffau et al. DIABETOLOGIA
- Short-Chain Fatty Acid Receptor and Its Contribution to Glucagon-Like Peptide-1 Release
- (2014) Izumi Kaji et al. DIGESTION
- Sodium butyrate, a HDAC inhibitor ameliorates eNOS, iNOS and TGF-β1-induced fibrogenesis, apoptosis and DNA damage in the kidney of juvenile diabetic rats
- (2014) Sabbir Khan et al. FOOD AND CHEMICAL TOXICOLOGY
- Valproate ameliorates thioacetamide-induced fibrosis by hepatic stellate cell inactivation
- (2014) JS Aher et al. HUMAN & EXPERIMENTAL TOXICOLOGY
- Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and -cell protection
- (2014) D. P. Christensen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibition of HDAC3 as a strategy for developing novel diabetes therapeutics
- (2014) Bennett C Meier et al. Epigenomics
- Genome-Wide DNA Methylation Analysis of Human Pancreatic Islets from Type 2 Diabetic and Non-Diabetic Donors Identifies Candidate Genes That Influence Insulin Secretion
- (2014) Tasnim Dayeh et al. PLoS Genetics
- Butyrate and other short-chain fatty acids increase the rate of lipolysis in 3T3-L1 adipocytes
- (2014) John M. Rumberger et al. PeerJ
- Developmental and environmental epigenetic programming of the endocrine pancreas: consequences for type 2 diabetes
- (2013) Ionel Sandovici et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Epigenetic changes in diabetes
- (2013) ST Keating et al. CLINICAL GENETICS
- Human Intestinal Microbiota and Type 1 Diabetes
- (2013) Outi Vaarala Current Diabetes Reports
- Transcriptional and epigenetic regulation in human islets
- (2013) Nuria C. Bramswig et al. DIABETOLOGIA
- Effects of short chain fatty acid producing bacteria on epigenetic regulation of FFAR3 in type 2 diabetes and obesity
- (2013) Marlene Remely et al. GENE
- G Protein-Coupled Receptor 43 Moderates Gut Inflammation Through Cytokine Regulation from Mononuclear Cells
- (2013) Ryuta Masui et al. INFLAMMATORY BOWEL DISEASES
- Microencapsulated sodium butyrate administered to patients with diverticulosis decreases incidence of diverticulitis—a prospective randomized study
- (2013) Lukasz Krokowicz et al. INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
- Butyrate Attenuates Inflammation and Lipolysis Generated by the Interaction of Adipocytes and Macrophages
- (2013) Hideo Ohira et al. Journal of Atherosclerosis and Thrombosis
- Beneficial Metabolic Effects of a Probiotic via Butyrate-induced GLP-1 Hormone Secretion
- (2013) Hariom Yadav et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inactivation of specific β cell transcription factors in type 2 diabetes
- (2013) Shuangli Guo et al. JOURNAL OF CLINICAL INVESTIGATION
- Histone deacetylase inhibitor suppresses virus-induced proinflammatory responses and type 1 diabetes
- (2013) Naoko Hara et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Sodium butyrate inhibits interferon-gamma induced indoleamine 2,3-dioxygenase expression via STAT1 in nasopharyngeal carcinoma cells
- (2013) Yu-Wen He et al. LIFE SCIENCES
- Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells
- (2013) Yukihiro Furusawa et al. NATURE
- Whole-body pharmacokinetics of HDAC inhibitor drugs, butyric acid, valproic acid and 4-phenylbutyric acid measured with carbon-11 labeled analogs by PET
- (2013) Sung Won Kim et al. NUCLEAR MEDICINE AND BIOLOGY
- Butyrate-Producing Probiotics Reduce Nonalcoholic Fatty Liver Disease Progression in Rats: New Insight into the Probiotics for the Gut-Liver Axis
- (2013) Hitoshi Endo et al. PLoS One
- Effects of Sodium Butyrate and Its Synthetic Amide Derivative on Liver Inflammation and Glucose Tolerance in an Animal Model of Steatosis Induced by High Fat Diet
- (2013) Giuseppina Mattace Raso et al. PLoS One
- High-Fat Diet Reduces the Formation of Butyrate, but Increases Succinate, Inflammation, Liver Fat and Cholesterol in Rats, while Dietary Fibre Counteracts These Effects
- (2013) Greta Jakobsdottir et al. PLoS One
- Tributyrin attenuates obesity-associated inflammation and insulin resistance in high-fat-fed mice
- (2012) Marco Aurélio Ramirez Vinolo et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure
- (2012) Chutima Talchai et al. CELL
- Inhibition of Histone Deacetylase 3 Protects Beta Cells from Cytokine-Induced Apoptosis
- (2012) Danny Hung-Chieh Chou et al. CHEMISTRY & BIOLOGY
- Class II Histone Deacetylases Downregulate GLUT4 Transcription in Response to Increased cAMP Signaling in Cultured Adipocytes and Fasting Mice
- (2012) J. C. Weems et al. DIABETES
- Fecal Microbiota Composition Differs Between Children With -Cell Autoimmunity and Those Without
- (2012) M. C. de Goffau et al. DIABETES
- Histone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic children
- (2012) M. Lundh et al. DIABETOLOGIA
- DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients
- (2012) Michael Volkmar et al. EMBO JOURNAL
- Profiles of Epigenetic Histone Post-translational Modifications at Type 1 Diabetes Susceptible Genes
- (2012) Feng Miao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Histone deacetylase 5 regulates glucose uptake and insulin action in muscle cells
- (2012) Suryaprakash Raichur et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- Prebiotics and the Health Benefits of Fiber: Current Regulatory Status, Future Research, and Goals
- (2012) Amy M. Brownawell et al. JOURNAL OF NUTRITION
- A high-fat diet decreases AMPK activity in multiple tissues in the absence of hyperglycemia or systemic inflammation in rats
- (2012) Christopher R. Lindholm et al. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY
- The Warburg Effect Dictates the Mechanism of Butyrate-Mediated Histone Acetylation and Cell Proliferation
- (2012) Dallas R. Donohoe et al. MOLECULAR CELL
- Butyrate and Propionate Protect against Diet-Induced Obesity and Regulate Gut Hormones via Free Fatty Acid Receptor 3-Independent Mechanisms
- (2012) Hua V. Lin et al. PLoS One
- Epigenetics and diabetes treatment: an unrealized promise?
- (2012) Nuria C. Bramswig et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Dietary Regulation of Histone Acetylases and Deacetylases for the Prevention of Metabolic Diseases
- (2012) Tho Pham et al. Nutrients
- The epigenetic effects of butyrate: potential therapeutic implications for clinical practice
- (2012) Roberto Berni Canani et al. Clinical Epigenetics
- Metabolic Homeostasis: HDACs Take Center Stage
- (2011) Jason Karpac et al. CELL
- Class IIa Histone Deacetylases Are Hormone-Activated Regulators of FOXO and Mammalian Glucose Homeostasis
- (2011) Maria M. Mihaylova et al. CELL
- Specific Control of Pancreatic Endocrine β- and δ-Cell Mass by Class IIa Histone Deacetylases HDAC4, HDAC5, and HDAC9
- (2011) Olivia Lenoir et al. DIABETES
- High expression of liver histone deacetylase 3 contributes to high-fat-diet-induced metabolic syndrome by suppressing the PPAR-γ and LXR-α-pathways in E3 rats
- (2011) Dongmin Li et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Unknown
- (2011) Eli Lewis et al. MOLECULAR MEDICINE
- Unknown
- (2011) Dan Christensen et al. MOLECULAR MEDICINE
- Type 1 Diabetes: Etiology, Immunology, and Therapeutic Strategies
- (2011) Tom L. Van Belle et al. PHYSIOLOGICAL REVIEWS
- Potential beneficial effects of butyrate in intestinal and extraintestinal diseases
- (2011) Roberto Berni Canani WORLD JOURNAL OF GASTROENTEROLOGY
- The role of class I histone deacetylase (HDAC) on gluconeogenesis in liver
- (2010) Hiroshi Oiso et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Lysine deacetylases are produced in pancreatic beta cells and are differentially regulated by proinflammatory cytokines
- (2010) M. Lundh et al. DIABETOLOGIA
- Class II Histone Deacetylases Limit GLUT4 Gene Expression during Adipocyte Differentiation
- (2010) Juston Weems et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Butyrate and Type 1 Diabetes Mellitus: Can We Fix the Intestinal Leak?
- (2010) Nan Li et al. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
- Epigenetic phenomena linked to diabetic complications
- (2010) Luciano Pirola et al. Nature Reviews Endocrinology
- Butyrate Improves Insulin Sensitivity and Increases Energy Expenditure in Mice
- (2009) Z. Gao et al. DIABETES
- Activation of the AMP activated protein kinase by short-chain fatty acids is the main mechanism underlying the beneficial effect of a high fiber diet on the metabolic syndrome
- (2009) Guo-Xin Hu et al. MEDICAL HYPOTHESES
- Health benefits of dietary fiber
- (2009) James W Anderson et al. NUTRITION REVIEWS
- Trichostatin A improves insulin stimulated glucose utilization and insulin signaling transduction through the repression of HDAC2
- (2008) Cheng Sun et al. BIOCHEMICAL PHARMACOLOGY
- AMP-Activated Protein Kinase Regulates GLUT4 Transcription by Phosphorylating Histone Deacetylase 5
- (2008) S. L. McGee et al. DIABETES
- GLUT4 Enhancer Factor (GEF) Interacts with MEF2A and HDAC5 to Regulate theGLUT4Promoter in Adipocytes
- (2008) David P. Sparling et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Targeting histone deacetylases for the treatment of disease
- (2008) M. W. Lawless et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Histone Deacetylase Inhibitors Modify Pancreatic Cell Fate Determination and Amplify Endocrine Progenitors
- (2008) C. Haumaitre et al. MOLECULAR AND CELLULAR BIOLOGY
- The many roles of histone deacetylases in development and physiology: implications for disease and therapy
- (2008) Michael Haberland et al. NATURE REVIEWS GENETICS
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