- Home
- Publications
- Publication Search
- Publication Details
Title
Emerging roles of ATRX in cancer
Authors
Keywords
-
Journal
Epigenomics
Volume 7, Issue 8, Pages 1365-1378
Publisher
Future Medicine Ltd
Online
2015-12-09
DOI
10.2217/epi.15.82
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Atrx promotes heterochromatin formation at retrotransposons
- (2015) D. Sadic et al. EMBO REPORTS
- Histone H3.3 maintains genome integrity during mammalian development
- (2015) Chuan-Wei Jang et al. GENES & DEVELOPMENT
- Histone H3.3 is required for endogenous retroviral element silencing in embryonic stem cells
- (2015) Simon J. Elsässer et al. NATURE
- Identification of protein complexes that bind to histone H3 combinatorial modifications using super-SILAC and weighted correlation network analysis
- (2015) Natalia Kunowska et al. NUCLEIC ACIDS RESEARCH
- Alternative lengthening of telomeres renders cancer cells hypersensitive to ATR inhibitors
- (2015) R. L. Flynn et al. SCIENCE
- CENP-A nucleosomes localize to transcription factor hotspots and subtelomeric sites in human cancer cells
- (2015) Rajbir K Athwal et al. Epigenetics & Chromatin
- Loss of ATRX, associated with DNA methylation pattern of chromosome end, impacted biological behaviors of astrocytic tumors
- (2015) Jinquan Cai et al. Oncotarget
- ATRX Plays a Key Role in Maintaining Silencing at Interstitial Heterochromatic Loci and Imprinted Genes
- (2015) Hsiao P.J. Voon et al. Cell Reports
- Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas
- (2015) Yuchen Jiao et al. Oncotarget
- Whole-exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma
- (2015) Kasthuri Kannan et al. Oncotarget
- ATRX Directs Binding of PRC2 to Xist RNA and Polycomb Targets
- (2014) Kavitha Sarma et al. CELL
- ATRX promotes gene expression by facilitating transcriptional elongation through guanine-rich coding regions
- (2014) Michael A. Levy et al. HUMAN MOLECULAR GENETICS
- Decreased Expression of the Chromatin Remodeler ATRX Associates with Melanoma Progression
- (2014) Zulekha A. Qadeer et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- An H3K9/S10 methyl-phospho switch modulates Polycomb and Pol II binding at repressed genes during differentiation
- (2014) Pierangela Sabbattini et al. MOLECULAR BIOLOGY OF THE CELL
- Mislocalization of the Centromeric Histone Variant CenH3/CENP-A in Human Cells Depends on the Chaperone DAXX
- (2014) Nicolas Lacoste et al. MOLECULAR CELL
- Analysis of neonatal brain lacking ATRX or MeCP2 reveals changes in nucleosome density, CTCF binding and chromatin looping
- (2014) Kristin D. Kernohan et al. NUCLEIC ACIDS RESEARCH
- ATRX Dysfunction Induces Replication Defects in Primary Mouse Cells
- (2014) David Clynes et al. PLoS One
- ATRX tolerates activity-dependent histone H3 methyl/phos switching to maintain repetitive element silencing in neurons
- (2014) Kyung-Min Noh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Use of human embryonic stem cells to model pediatric gliomas with H3.3K27M histone mutation
- (2014) Kosuke Funato et al. SCIENCE
- Recurrent Somatic Structural Variations Contribute to Tumorigenesis in Pediatric Osteosarcoma
- (2014) Xiang Chen et al. Cell Reports
- ATRX is required for maintenance of the neuroprogenitor cell pool in the embryonic mouse brain
- (2014) K. Ritchie et al. Biology Open
- Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas
- (2013) Sebastian Bender et al. CANCER CELL
- An AT-Hook Domain in MeCP2 Determines the Clinical Course of Rett Syndrome and Related Disorders
- (2013) Steven Andrew Baker et al. CELL
- Dynamics of histone H3.3 deposition in proliferating and senescent cells reveals a DAXX-dependent targeting to PML-NBs important for pericentromeric heterochromatin organization
- (2013) Armelle Corpet et al. CELL CYCLE
- Loss of DAXX and ATRX Are Associated With Chromosome Instability and Reduced Survival of Patients With Pancreatic Neuroendocrine Tumors
- (2013) Ilaria Marinoni et al. GASTROENTEROLOGY
- The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression
- (2013) K.-M. Chan et al. GENES & DEVELOPMENT
- Clinicopathologic significance of immunostaining of α-thalassemia/mental retardation syndrome X-linked protein and death domain–associated protein in neuroendocrine tumors
- (2013) Shi-Fan Chen et al. HUMAN PATHOLOGY
- Alpha Thalassemia/Mental Retardation Syndrome X-linked Gene Product ATRX Is Required for Proper Replication Restart and Cellular Resistance to Replication Stress
- (2013) Justin Wai-Chung Leung et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Atrx deficiency induces telomere dysfunction, endocrine defects, and reduced life span
- (2013) L. Ashley Watson et al. JOURNAL OF CLINICAL INVESTIGATION
- Quantitative visualization of DNA G-quadruplex structures in human cells
- (2013) Giulia Biffi et al. Nature Chemistry
- PML bodies provide an important platform for the maintenance of telomeric chromatin integrity in embryonic stem cells
- (2013) Fiona T. M. Chang et al. NUCLEIC ACIDS RESEARCH
- AKT Signaling as a Novel Factor Associated with In Vitro Resistance of Human AML to Gemtuzumab Ozogamicin
- (2013) David B. Rosen et al. PLoS One
- Spontaneous slow replication fork progression elicits mitosis alterations in homologous recombination-deficient mammalian cells
- (2013) T. Wilhelm et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal
- (2013) P. J. Killela et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric Glioblastoma
- (2013) P. W. Lewis et al. SCIENCE
- The chromatin remodeller ATRX: a repeat offender in human disease
- (2013) David Clynes et al. TRENDS IN BIOCHEMICAL SCIENCES
- Genome-wide incorporation dynamics reveal distinct categories of turnover for the histone variant H3.3
- (2013) Daniel C Kraushaar et al. GENOME BIOLOGY
- Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations
- (2012) Xiao-Yang Liu et al. ACTA NEUROPATHOLOGICA
- Small Cell and Large Cell Neuroendocrine Carcinomas of the Pancreas are Genetically Similar and Distinct From Well-differentiated Pancreatic Neuroendocrine Tumors
- (2012) Shinichi Yachida et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma
- (2012) Dominik Sturm et al. CANCER CELL
- ATRX-mediated chromatin association of histone variant macroH2A1 regulates -globin expression
- (2012) K. Ratnakumar et al. GENES & DEVELOPMENT
- D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function
- (2012) M. Sasaki et al. GENES & DEVELOPMENT
- Variant repeats are interspersed throughout the telomeres and recruit nuclear receptors in ALT cells
- (2012) Dimitri Conomos et al. JOURNAL OF CELL BIOLOGY
- Linking abnormal mitosis to the acquisition of DNA damage
- (2012) Neil J. Ganem et al. JOURNAL OF CELL BIOLOGY
- Compromised genomic integrity impedes muscle growth after Atrx inactivation
- (2012) Michael S. Huh et al. JOURNAL OF CLINICAL INVESTIGATION
- DNA breaks and chromosome pulverization from errors in mitosis
- (2012) Karen Crasta et al. NATURE
- Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
- (2012) Jeremy Schwartzentruber et al. NATURE
- IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics
- (2012) Masato Sasaki et al. NATURE
- Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes
- (2012) Jan J. Molenaar et al. NATURE
- Loss of Wild-Type ATRX Expression in Somatic Cell Hybrids Segregates with Activation of Alternative Lengthening of Telomeres
- (2012) Kylie Bower et al. PLoS One
- Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway
- (2012) Courtney A. Lovejoy et al. PLoS Genetics
- Prevalence of the Alternative Lengthening of Telomeres Telomere Maintenance Mechanism in Human Cancer Subtypes
- (2011) Christopher M. Heaphy et al. AMERICAN JOURNAL OF PATHOLOGY
- The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
- (2011) Rasheduzzaman Chowdhury et al. EMBO REPORTS
- The ATRX-ADD domain binds to H3 tail peptides and reads the combined methylation state of K4 and K9
- (2011) Arunkumar Dhayalan et al. HUMAN MOLECULAR GENETICS
- Functional significance of mutations in the Snf2 domain of ATRX
- (2011) Matthew Mitson et al. HUMAN MOLECULAR GENETICS
- ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome
- (2011) Shigeki Iwase et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Combinatorial readout of histone H3 modifications specifies localization of ATRX to heterochromatin
- (2011) Sebastian Eustermann et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Mutations in CIC and FUBP1 Contribute to Human Oligodendroglioma
- (2011) C. Bettegowda et al. SCIENCE
- New Epigenetic Drivers of Cancers
- (2011) S. J. Elsasser et al. SCIENCE
- Altered Telomeres in Tumors with ATRX and DAXX Mutations
- (2011) C. M. Heaphy et al. SCIENCE
- DAXX/ATRX, MEN1, and mTOR Pathway Genes Are Frequently Altered in Pancreatic Neuroendocrine Tumors
- (2011) Y. Jiao et al. SCIENCE
- R132H-mutation of isocitrate dehydrogenase-1 is not sufficient for HIF-1α upregulation in adult glioma
- (2010) Susan C. Williams et al. ACTA NEUROPATHOLOGICA
- Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma
- (2010) Houtan Noushmehr et al. CANCER CELL
- Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions
- (2010) Aaron D. Goldberg et al. CELL
- ATR-X Syndrome Protein Targets Tandem Repeats and Influences Allele-Specific Expression in a Size-Dependent Manner
- (2010) Martin J. Law et al. CELL
- ATRX: Taming tandem repeats
- (2010) Richard J. Gibbons et al. CELL CYCLE
- ATRX Partners with Cohesin and MeCP2 and Contributes to Developmental Silencing of Imprinted Genes in the Brain
- (2010) Kristin D. Kernohan et al. DEVELOPMENTAL CELL
- The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3
- (2010) P. Drane et al. GENES & DEVELOPMENT
- ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells
- (2010) L. H. Wong et al. GENOME RESEARCH
- The histone variant macroH2A suppresses melanoma progression through regulation of CDK8
- (2010) Avnish Kapoor et al. NATURE
- Alternative lengthening of telomeres: models, mechanisms and implications
- (2010) Anthony J. Cesare et al. NATURE REVIEWS GENETICS
- Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres
- (2010) P. W. Lewis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Loss of Maternal ATRX Results in Centromere Instability and Aneuploidy in the Mammalian Oocyte and Pre-Implantation Embryo
- (2010) Claudia Baumann et al. PLoS Genetics
- HJURP Is a Cell-Cycle-Dependent Maintenance and Deposition Factor of CENP-A at Centromeres
- (2009) Elaine M. Dunleavy et al. CELL
- Centromere-Specific Assembly of CENP-A Nucleosomes Is Mediated by HJURP
- (2009) Daniel R. Foltz et al. CELL
- Non-B DNA structure-induced genetic instability and evolution
- (2009) Junhua Zhao et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- A ‘higher order’ of telomere regulation: telomere heterochromatin and telomeric RNAs
- (2009) Stefan Schoeftner et al. EMBO JOURNAL
- Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
- (2009) Lenny Dang et al. NATURE
- Surgical management of pancreatic endocrine tumors
- (2009) Volker Fendrich et al. Nature Reviews Clinical Oncology
- G-quadruplex structures: in vivo evidence and function
- (2009) Hans J. Lipps et al. TRENDS IN CELL BIOLOGY
- The SWI/SNF protein ATRX co-regulates pseudoautosomal genes that have translocated to autosomes in the mouse genome.
- (2008) Michael A Levy et al. BMC GENOMICS
- ATRX marks the inactive X chromosome (Xi) in somatic cells and during imprinted X chromosome inactivation in trophoblast stem cells
- (2008) Claudia Baumann et al. CHROMOSOMA
- Mutations in the chromatin-associated protein ATRX
- (2008) Richard J. Gibbons et al. HUMAN MUTATION
- Loss of ATRX leads to chromosome cohesion and congression defects
- (2008) Kieran Ritchie et al. JOURNAL OF CELL BIOLOGY
- Dynamics of component exchange at PML nuclear bodies
- (2008) S. Weidtkamp-Peters et al. JOURNAL OF CELL SCIENCE
- Neuronal Death Resulting from Targeted Disruption of the Snf2 Protein ATRX Is Mediated by p53
- (2008) C. Seah et al. JOURNAL OF NEUROSCIENCE
- The HP1–p150/CAF-1 interaction is required for pericentric heterochromatin replication and S-phase progression in mouse cells
- (2008) Jean-Pierre Quivy et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- An Integrated Genomic Analysis of Human Glioblastoma Multiforme
- (2008) D. W. Parsons et al. SCIENCE
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started