Alpha Thalassemia/Mental Retardation Syndrome X-linked Gene Product ATRX Is Required for Proper Replication Restart and Cellular Resistance to Replication Stress

CDK targeting of NBS1 promotes DNA-end resection, replication restart and homologous recombination

(2012) Jacob Falck et al.   EMBO REPORTS

ZRANB3 is a structure-specific ATP-dependent endonuclease involved in replication stress response

(2012) R. Weston et al.   GENES & DEVELOPMENT

Proliferating Cell Nuclear Antigen (PCNA)-binding Protein C1orf124 Is a Regulator of Translesion Synthesis

(2012) Gargi Ghosal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Compromised genomic integrity impedes muscle growth after Atrx inactivation

(2012) Michael S. Huh et al.   JOURNAL OF CLINICAL INVESTIGATION

The HARP-like Domain-Containing Protein AH2/ZRANB3 Binds to PCNA and Participates in Cellular Response to Replication Stress

(2012) Jingsong Yuan et al.   MOLECULAR CELL

Polyubiquitinated PCNA Recruits the ZRANB3 Translocase to Maintain Genomic Integrity after Replication Stress

(2012) Alberto Ciccia et al.   MOLECULAR CELL

Fanconi anemia (FA) binding protein FAAP20 stabilizes FA complementation group A (FANCA) and participates in interstrand cross-link repair

(2012) J. W. C. Leung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway

(2012) Courtney A. Lovejoy et al.   PLoS Genetics

ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome

(2011) Shigeki Iwase et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Role of ATRX in chromatin structure and function: implications for chromosome instability and human disease

(2011) Rabindranath De La Fuente et al.   REPRODUCTION

Altered Telomeres in Tumors with ATRX and DAXX Mutations

(2011) C. M. Heaphy et al.   SCIENCE

Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions

(2010) Aaron D. Goldberg et al.   CELL

ATR-X Syndrome Protein Targets Tandem Repeats and Influences Allele-Specific Expression in a Size-Dependent Manner

(2010) Martin J. Law et al.   CELL

The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3

(2010) P. Drane et al.   GENES & DEVELOPMENT

ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells

(2010) L. H. Wong et al.   GENOME RESEARCH

Chk1 inhibits replication factory activation but allows dormant origin firing in existing factories

(2010) Xin Quan Ge et al.   JOURNAL OF CELL BIOLOGY

Hydroxyurea-Stalled Replication Forks Become Progressively Inactivated and Require Two Different RAD51-Mediated Pathways for Restart and Repair

(2010) Eva Petermann et al.   MOLECULAR CELL

Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres

(2010) P. W. Lewis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Loss of Maternal ATRX Results in Centromere Instability and Aneuploidy in the Mammalian Oocyte and Pre-Implantation Embryo

(2010) Claudia Baumann et al.   PLoS Genetics

The MRX complex stabilizes the replisome independently of the S phase checkpoint during replication stress

(2009) Mireille Tittel-Elmer et al.   EMBO JOURNAL

PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination

(2009) Helen E Bryant et al.   EMBO JOURNAL

The annealing helicase HARP protects stalled replication forks

(2009) J. Yuan et al.   GENES & DEVELOPMENT

The annealing helicase SMARCAL1 maintains genome integrity at stalled replication forks

(2009) C. E. Bansbach et al.   GENES & DEVELOPMENT

The annealing helicase HARP is recruited to DNA repair sites via an interaction with RPA

(2009) T. Yusufzai et al.   GENES & DEVELOPMENT

Involvement of a chromatin remodeling complex in damage tolerance during DNA replication

(2009) Karina B Falbo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Probing PML body function in ALT cells reveals spatiotemporal requirements for telomere recombination

(2009) I. Draskovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Loss of ATRX leads to chromosome cohesion and congression defects

(2008) Kieran Ritchie et al.   JOURNAL OF CELL BIOLOGY