Identification of thioridazine, an antipsychotic drug, as an antiglioblastoma and anticancer stem cell agent using public gene expression data

Genome-wide shRNA screen revealed integrated mitogenic signaling between dopamine receptor D2 (DRD2) and epidermal growth factor receptor (EGFR) in glioblastoma

(2015) Jie Li et al.   Oncotarget

Long-Term Artificial Selection Reveals a Role of TCTP in Autophagy in Mammalian Cells

(2014) Ke Chen et al.   MOLECULAR BIOLOGY AND EVOLUTION

Role of AMP-activated protein kinase in cross-talk between apoptosis and autophagy in human colon cancer

(2014) X Song et al.   Cell Death & Disease

Inverse cancer comorbidity: a serendipitous opportunity to gain insight into CNS disorders

(2013) Rafael Tabarés-Seisdedos et al.   NATURE REVIEWS NEUROSCIENCE

Mmi1, the Yeast Homologue of Mammalian TCTP, Associates with Stress Granules in Heat-Shocked Cells and Modulates Proteasome Activity

(2013) Mark Rinnerthaler et al.   PLoS One

Identification of Drugs Including a Dopamine Receptor Antagonist that Selectively Target Cancer Stem Cells

(2012) Eleftherios Sachlos et al.   CELL

Regulation of AMPK by the Ubiquitin Proteasome System

(2011) Makhosazane Zungu et al.   AMERICAN JOURNAL OF PATHOLOGY

Autophagy in Brain Tumors: A New Target for Therapeutic Intervention

(2011) Niroop Kaza et al.   BRAIN PATHOLOGY

MAP Kinase-Interacting Kinase 1 Regulates SMAD2-Dependent TGF-  Signaling Pathway in Human Glioblastoma

(2011) M. Grzmil et al.   CANCER RESEARCH

AMPK -> ULK1 -> Autophagy

(2011) P. J. Roach   MOLECULAR AND CELLULAR BIOLOGY

Integration and analysis of genome-scale data from gliomas

(2011) Gregory Riddick et al.   Nature Reviews Neurology

Autophagy induced by valproic acid is associated with oxidative stress in glioma cell lines

(2011) J. Fu et al.   NEURO-ONCOLOGY

Is there a common upstream link for autophagic and apoptotic cell death in human high-grade gliomas?

(2011) L. Emdad et al.   NEURO-ONCOLOGY

Pathway inhibition: emerging molecular targets for treating glioblastoma

(2011) W. Wick et al.   NEURO-ONCOLOGY

Autophagy Interplay with Apoptosis and Cell Cycle Regulation in the Growth Inhibiting Effect of Resveratrol in Glioma Cells

(2011) Eduardo C. Filippi-Chiela et al.   PLoS One

The incidence and relative risk factors for developing cancer among patients with schizophrenia: A nine-year follow-up study

(2011) Frank Huang-Chih Chou et al.   SCHIZOPHRENIA RESEARCH

Using a Stem Cell-Based Signature to Guide Therapeutic Selection in Cancer

(2010) I. Shats et al.   CANCER RESEARCH

PI3Kinase signaling in glioblastoma

(2010) M. M. Lino et al.   JOURNAL OF NEURO-ONCOLOGY

Survival signalling and apoptosis resistance in glioblastomas: opportunities for targeted therapeutics

(2010) Camilla Krakstad et al.   Molecular Cancer

Systems analysis of EGF receptor signaling dynamics with microwestern arrays

(2010) Mark F Ciaccio et al.   NATURE METHODS

Intrinsic Gene Expression Profiles of Gliomas Are a Better Predictor of Survival than Histology

(2009) L. A.M. Gravendeel et al.   CANCER RESEARCH

EZH2 Is Essential for Glioblastoma Cancer Stem Cell Maintenance

(2009) M.-L. Suva et al.   CANCER RESEARCH

MGMT promoter methylation in malignant gliomas: ready for personalized medicine?

(2009) Michael Weller et al.   Nature Reviews Neurology

Comparative analyses of gene copy number and mRNA expression in glioblastoma multiforme tumors and xenografts

(2009) J. Graeme Hodgson et al.   NEURO-ONCOLOGY

Module Map of Stem Cell Genes Guides Creation of Epithelial Cancer Stem Cells

(2008) David J. Wong et al.   Cell Stem Cell

Stem Cell–Related “Self-Renewal” Signature and High Epidermal Growth Factor Receptor Expression Associated With Resistance to Concomitant Chemoradiotherapy in Glioblastoma

(2008) Anastasia Murat et al.   JOURNAL OF CLINICAL ONCOLOGY

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

(2008) D. W. Parsons et al.   SCIENCE