In vivoepigenetic reprogramming of primary human colon cancer cells enhances metastases

Inter- and intra-tumor profiling of multi-regional colon cancer and metastasis

(2015) Akihiro Kogita et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hotspot Mutation Panel Testing Reveals Clonal Evolution in a Study of 265 Paired Primary and Metastatic Tumors

(2015) R. S. Goswami et al.   CLINICAL CANCER RESEARCH

Reprogramming of primary human Philadelphia chromosome-positive B cell acute lymphoblastic leukemia cells into nonleukemic macrophages

(2015) James Scott McClellan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Cancer Reprogramming Method Using MicroRNAs as a Novel Therapeutic Approach against Colon Cancer

(2014) Susumu Miyazaki et al.   ANNALS OF SURGICAL ONCOLOGY

Premature Termination of Reprogramming In Vivo Leads to Cancer Development through Altered Epigenetic Regulation

(2014) Kotaro Ohnishi et al.   CELL

Nanog Is Dispensable for the Generation of Induced Pluripotent Stem Cells

(2014) Benjamin A. Schwarz et al.   CURRENT BIOLOGY

A novel genome-wide in vivo screen for metastatic suppressors in human colon cancer identifies the positive WNT-TCF pathway modulators TMED3 and SOX12

(2014) A. Duquet et al.   EMBO Molecular Medicine

Divergent reprogramming routes lead to alternative stem-cell states

(2014) Peter D. Tonge et al.   NATURE

SOX2 regulates self-renewal and tumorigenicity of human melanoma-initiating cells

(2014) R Santini et al.   ONCOGENE

Induction of Cancer Stem Cell Properties in Colon Cancer Cells by Defined Factors

(2014) Nobu Oshima et al.   PLoS One

Context-dependent signal integration by the GLI code: The oncogenic load, pathways, modifiers and implications for cancer therapy

(2014) Fritz Aberger et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

NANOG promotes liver cancer cell invasion by inducing epithelial–mesenchymal transition through NODAL/SMAD3 signaling pathway

(2013) Chun Sun et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Reprogramming in vivo produces teratomas and iPS cells with totipotency features

(2013) María Abad et al.   NATURE

Chromatin dynamics during cellular reprogramming

(2013) Effie Apostolou et al.   NATURE

Mechanisms and models of somatic cell reprogramming

(2013) Yosef Buganim et al.   NATURE REVIEWS GENETICS

The pluripotency factor nanog promotes breast cancer tumorigenesis and metastasis

(2013) X Lu et al.   ONCOGENE

Epigenetic Regulation of Pluripotent Genes Mediates Stem Cell Features in Human Hepatocellular Carcinoma and Cancer Cell Lines

(2013) Xiao Qi Wang et al.   PLoS One

A Molecular Roadmap of Reprogramming Somatic Cells into iPS Cells

(2012) Jose M. Polo et al.   CELL

EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness

(2012) Ester Sánchez-Tilló et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

NANOG modulates stemness in human colorectal cancer

(2012) J Zhang et al.   ONCOGENE

The Intestinal Stem Cell Signature Identifies Colorectal Cancer Stem Cells and Predicts Disease Relapse

(2011) Anna Merlos-Suárez et al.   Cell Stem Cell

Hedgehog Signaling and the Gli Code in Stem Cells, Cancer, and Metastases

(2011) A. Ruiz i Altaba   Science Signaling

Over-expression of Nanog predicts tumor progression and poor prognosis in colorectal cancer

(2010) Hui-Min Meng et al.   CANCER BIOLOGY & THERAPY

NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53

(2010) Marie Zbinden et al.   EMBO JOURNAL

Loss of WNT-TCF addiction and enhancement of HH-GLI1 signalling define the metastatic transition of human colon carcinomas

(2010) Frédéric Varnat et al.   EMBO Molecular Medicine

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

(2010) Shinichi Yachida et al.   NATURE

Context-dependent Regulation of the GLI Code in Cancer by HEDGEHOG and Non-HEDGEHOG Signals

(2010) B. Stecca et al.   Journal of Molecular Cell Biology

Nanog Is the Gateway to the Pluripotent Ground State

(2009) Jose Silva et al.   CELL

Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion

(2009) Frédéric Varnat et al.   EMBO Molecular Medicine

Defined factors induce reprogramming of gastrointestinal cancer cells

(2009) N. Miyoshi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional Evidence that the Self-Renewal GeneNANOGRegulates Human Tumor Development

(2009) Collene R. Jeter et al.   STEM CELLS

Periodic Activation of Wnt/β-Catenin Signaling Enhances Somatic Cell Reprogramming Mediated by Cell Fusion

(2008) Frederic Lluis et al.   Cell Stem Cell

Wnt Signaling Promotes Reprogramming of Somatic Cells to Pluripotency

(2008) Alexander Marson et al.   Cell Stem Cell

Sequential Expression of Pluripotency Markers during Direct Reprogramming of Mouse Somatic Cells

(2008) Tobias Brambrink et al.   Cell Stem Cell

An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors

(2008) Ittai Ben-Porath et al.   NATURE GENETICS

Comparative lesion sequencing provides insights into tumor evolution

(2008) S. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclear Reprogramming in Cells

(2008) J. B. Gurdon et al.   SCIENCE

Induced Pluripotent Stem Cell Generation Using a Single Lentiviral Stem Cell Cassette

(2008) Cesar A. Sommer et al.   STEM CELLS