A key role for PTP1B in dendritic cell maturation, migration, and T cell activation

A crucial role for  2 integrins in podosome formation, dynamics and Toll-like-receptor-signaled disassembly in dendritic cells

(2014) C. Gawden-Bone et al.   JOURNAL OF CELL SCIENCE

The protein tyrosine phosphatase PTP1B is a negative regulator of CD40 and BAFF-R signaling and controls B cell autoimmunity

(2014) David Medgyesi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The small GTPase Rap1b negatively regulates neutrophil chemotaxis and transcellular diapedesis by inhibiting Akt activation

(2014) Sachin Kumar et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lipopolysaccharide-Activated IL-10-Secreting Dendritic Cells Suppress Experimental Autoimmune Uveoretinitis by MHCII-Dependent Activation of CD62L-Expressing Regulatory T Cells

(2014) A. W. T. Lau et al.   JOURNAL OF IMMUNOLOGY

Protein tyrosine phosphatases ε and α perform nonredundant roles in osteoclasts

(2014) Eynat Finkelshtein et al.   MOLECULAR BIOLOGY OF THE CELL

PTP1B: A simple enzyme for a complex world

(2013) Matthew Feldhammer et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Myeloid-Cell Protein Tyrosine Phosphatase-1B Deficiency in Mice Protects Against High-Fat Diet and Lipopolysaccharide-Induced Inflammation, Hyperinsulinemia, and Endotoxemia Through an IL-10 STAT3-Dependent Mechanism

(2013) L. Grant et al.   DIABETES

PTP1B promotes focal complex maturation, lamellar persistence and directional migration

(2013) J. E. Burdisso et al.   JOURNAL OF CELL SCIENCE

Signaling inputs to invadopodia and podosomes

(2013) D. Hoshino et al.   JOURNAL OF CELL SCIENCE

Protein Tyrosine Phosphatase 1B Deficiency Ameliorates Murine Experimental Colitis via the Expansion of Myeloid-Derived Suppressor Cells

(2013) Jing Zhang et al.   PLoS One

Protein tyrosine phosphatase PTP1B in cell adhesion and migration

(2013) Carlos O Arregui et al.   Cell Adhesion & Migration

Decisions About Dendritic Cells: Past, Present, and Future

(2012) Ralph M. Steinman   Annual Review of Immunology

Protein tyrosine phosphatase SHP2 suppresses podosome rosette formation in Src-transformed fibroblasts

(2012) Y.-R. Pan et al.   JOURNAL OF CELL SCIENCE

Antigen Recognition Is Facilitated by Invadosome-like Protrusions Formed by Memory/Effector T Cells

(2012) P. T. Sage et al.   JOURNAL OF IMMUNOLOGY

ER-Bound Protein Tyrosine Phosphatase PTP1B Interacts with Src at the Plasma Membrane/Substrate Interface

(2012) Melisa C. Monteleone et al.   PLoS One

Essential role of protein tyrosine phosphatase 1B in obesity-induced inflammation and peripheral insulin resistance during aging

(2011) Águeda González-Rodríguez et al.   AGING CELL

Regulation and function of the E-cadherin/catenin complex in cells of the monocyte-macrophage lineage and DCs

(2011) J. Van den Bossche et al.   BLOOD

Tyrosine phosphorylation of WASP promotes calpain-mediated podosome disassembly

(2011) L. Macpherson et al.   HAEMATOLOGICA

Fascin1 Promotes Cell Migration of Mature Dendritic Cells

(2011) Y. Yamakita et al.   JOURNAL OF IMMUNOLOGY

Dendritic cell podosomes are protrusive and invade the extracellular matrix using metalloproteinase MMP-14

(2010) C. Gawden-Bone et al.   JOURNAL OF CELL SCIENCE

Vav1 Regulates the Migration and Adhesion of Dendritic Cells

(2009) D. R. Spurrell et al.   JOURNAL OF IMMUNOLOGY

Protein Tyrosine Phosphatase Epsilon Regulates Integrin-mediated Podosome Stability in Osteoclasts by Activating Src

(2009) Shira Granot-Attas et al.   MOLECULAR BIOLOGY OF THE CELL

Liver-Specific Deletion of Protein-Tyrosine Phosphatase 1B (PTP1B) Improves Metabolic Syndrome and Attenuates Diet-Induced Endoplasmic Reticulum Stress

(2008) M. Delibegovic et al.   DIABETES

A role for ARF6 in dendritic cell podosome formation and migration

(2008) Henrik G. Svensson et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mechanisms and Consequences of Dendritic Cell Migration

(2008) David Alvarez et al.   IMMUNITY

Calpain 2 and PTP1B function in a novel pathway with Src to regulate invadopodia dynamics and breast cancer cell invasion

(2008) Christa L. Cortesio et al.   JOURNAL OF CELL BIOLOGY

TLR ligand–induced podosome disassembly in dendritic cells is ADAM17 dependent

(2008) Michele A. West et al.   JOURNAL OF CELL BIOLOGY

Investigation of Protein-tyrosine Phosphatase 1B Function by Quantitative Proteomics

(2008) Philipp Mertins et al.   MOLECULAR & CELLULAR PROTEOMICS

Phosphatase PTP1B negatively regulates MyD88- and TRIF-dependent proinflammatory cytokine and type I interferon production in TLR-triggered macrophages

(2008) Hongmei Xu et al.   MOLECULAR IMMUNOLOGY

Migration of Dendritic Cell Subsets and their Precursors

(2007) Gwendalyn J. Randolph et al.   Annual Review of Immunology

Paxillin Phosphorylation Controls Invadopodia/Podosomes Spatiotemporal Organization

(2007) Cédric Badowski et al.   MOLECULAR BIOLOGY OF THE CELL

The Tyrosine Kinase Activity of c-Src Regulates Actin Dynamics and Organization of Podosomes in Osteoclasts

(2007) Olivier Destaing et al.   MOLECULAR BIOLOGY OF THE CELL