Essential role of protein tyrosine phosphatase 1B in obesity-induced inflammation and peripheral insulin resistance during aging

Fat tissue, aging, and cellular senescence

(2010) Tamara Tchkonia et al.   AGING CELL

Macrophages, Inflammation, and Insulin Resistance

(2010) Jerrold M. Olefsky et al.   Annual Review of Physiology

PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice

(2010) Ryoichi Banno et al.   JOURNAL OF CLINICAL INVESTIGATION

Palmitoleate attenuates palmitate-induced Bim and PUMA up-regulation and hepatocyte lipoapoptosis

(2010) Yuko Akazawa et al.   JOURNAL OF HEPATOLOGY

Prevention of Steatosis by Hepatic JNK1

(2009) Guadalupe Sabio et al.   Cell Metabolism

Inhibition of PTP1B Restores IRS1-Mediated Hepatic Insulin Signaling in IRS2-Deficient Mice

(2009) A. Gonzalez-Rodriguez et al.   DIABETES

Physical Inactivity and Obesity Underlie the Insulin Resistance of Aging

(2009) F. Amati et al.   DIABETES CARE

Serum and muscle interleukin-15 levels decrease in aging mice: Correlation with declines in soluble interleukin-15 receptor alpha expression

(2009) LeBris S. Quinn et al.   EXPERIMENTAL GERONTOLOGY

S6K1 deficiency protects against apoptosis in hepatocytes

(2009) Águeda González-Rodriguez et al.   HEPATOLOGY

Insulin Induces REDD1 Expression through Hypoxia-inducible Factor 1 Activation in Adipocytes

(2009) Claire Regazzetti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deletion of Fas in adipocytes relieves adipose tissue inflammation and hepatic manifestations of obesity in mice

(2009) Stephan Wueest et al.   JOURNAL OF CLINICAL INVESTIGATION

A crucial role for adipose tissue p53 in the regulation of insulin resistance

(2009) Tohru Minamino et al.   NATURE MEDICINE

Fat Talks, Liver and Muscle Listen

(2008) Jerrold M. Olefsky   CELL

Liver-Specific Deletion of Protein-Tyrosine Phosphatase 1B (PTP1B) Improves Metabolic Syndrome and Attenuates Diet-Induced Endoplasmic Reticulum Stress

(2008) M. Delibegovic et al.   DIABETES

Obesity and the Metabolic Syndrome in the Elderly – A Mini-Review

(2008) Monika Lechleitner   GERONTOLOGY

Protein-tyrosine Phosphatase 1B Expression Is Induced by Inflammationin Vivo

(2008) Janice M. Zabolotny et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin sensitivity: modulation by nutrients and inflammation

(2008) Simon Schenk et al.   JOURNAL OF CLINICAL INVESTIGATION