The pathology roadmap in Parkinson disease

Physiological Phenotype and Vulnerability in Parkinson's Disease

(2013) D. J. Surmeier et al.   Cold Spring Harbor Perspectives in Medicine

Use of Calcium Channel Blockers and Parkinson’s Disease

(2012) Björn Pasternak et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Lewy pathology and neurodegeneration in premotor Parkinson's disease

(2012) Kelly Del Tredici et al.   MOVEMENT DISORDERS

Calcium entry induces mitochondrial oxidant stress in vagal neurons at risk in Parkinson's disease

(2012) Joshua A Goldberg et al.   NATURE NEUROSCIENCE

Alpha-Synuclein Cell-to-Cell Transfer and Seeding in Grafted Dopaminergic Neurons In Vivo

(2012) Elodie Angot et al.   PLoS One

Pathological  -Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice

(2012) K. C. Luk et al.   SCIENCE

Chronic Constipation in the Elderly

(2011) Juan F Gallegos-Orozco et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Lysosomal Ca2+ homeostasis: Role in pathogenesis of lysosomal storage diseases

(2011) Emyr Lloyd-Evans et al.   CELL CALCIUM

Lewy Bodies and Olfactory Dysfunction in Old Age

(2011) R. S. Wilson et al.   CHEMICAL SENSES

Direct Membrane Association Drives Mitochondrial Fission by the Parkinson Disease-associated Protein α-Synuclein

(2011) Ken Nakamura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Essential Roles of Enteric Neuronal Serotonin in Gastrointestinal Motility and the Development/Survival of Enteric Dopaminergic Neurons

(2011) Z. Li et al.   JOURNAL OF NEUROSCIENCE

Intrinsic Bioenergetic Properties and Stress Sensitivity of Dopaminergic Synaptosomes

(2011) S. W. Choi et al.   JOURNAL OF NEUROSCIENCE

Dopamine-depletion and increased α-synuclein load induce degeneration of cortical cholinergic fibers in mice

(2011) Éva M. Szegő et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Autonomic involvement in Parkinson's disease: Pathology, pathophysiology, clinical features and possible peripheral biomarkers

(2011) Maria G. Cersosimo et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Clinical correlates of similar pathologies in parkinsonian syndromes

(2011) Yun Ju Christine Song et al.   MOVEMENT DISORDERS

Neuropathology of sporadic Parkinson's disease: Evaluation and changes of concepts

(2011) Kurt A. Jellinger   MOVEMENT DISORDERS

Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death

(2011) Laura A. Volpicelli-Daley et al.   NEURON

Unmyelinated axons are more vulnerable to degeneration than myelinated axons of the cardiac nerve in Parkinson's disease

(2011) S. Orimo et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Lewy pathology in the submandibular gland of individuals with incidental Lewy body disease and sporadic Parkinson’s disease

(2010) Kelly Del Tredici et al.   ACTA NEUROPATHOLOGICA

α-Synucleinopathy in the human olfactory system in Parkinson’s disease: involvement of calcium-binding protein- and substance P-positive cells

(2010) Isabel Ubeda-Bañon et al.   ACTA NEUROPATHOLOGICA

Cell-Produced  -Synuclein Is Secreted in a Calcium-Dependent Manner by Exosomes and Impacts Neuronal Survival

(2010) E. Emmanouilidou et al.   JOURNAL OF NEUROSCIENCE

Raised calcium promotes α-synuclein aggregate formation

(2010) S. Nath et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1

(2010) Jaime N. Guzman et al.   NATURE

Increased Expression of α-Synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering after Endocytosis

(2010) Venu M. Nemani et al.   NEURON

Colonic Biopsies to Assess the Neuropathology of Parkinson's Disease and Its Relationship with Symptoms

(2010) Thibaud Lebouvier et al.   PLoS One

Diminished tyrosine hydroxylase immunoreactivity in the cardiac conduction system and myocardium in Parkinson’s disease: an anatomical study

(2009) Estifanos Ghebremedhin et al.   ACTA NEUROPATHOLOGICA

Do mtDNA deletions drive premature aging in mtDNA mutator mice?

(2009) Yevgenya Kraytsberg et al.   AGING CELL

Molecular Circuitry of Endocytosis at Nerve Terminals

(2009) Jeremy Dittman et al.   Annual Review of Cell and Developmental Biology

Spare respiratory capacity, oxidative stress and excitotoxicity

(2009) David G. Nicholls   BIOCHEMICAL SOCIETY TRANSACTIONS

The second brain and Parkinson’s disease

(2009) Thibaud Lebouvier et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Endogenous Calcium Buffering Capacity of Substantia Nigral Dopamine Neurons

(2009) R. C. Foehring et al.   JOURNAL OF NEUROPHYSIOLOGY

Robust Pacemaking in Substantia Nigra Dopaminergic Neurons

(2009) J. N. Guzman et al.   JOURNAL OF NEUROSCIENCE

Nonequilibrium Calcium Dynamics Regulate the Autonomous Firing Pattern of Rat Striatal Cholinergic Interneurons

(2009) J. A. Goldberg et al.   JOURNAL OF NEUROSCIENCE

Cav1.3 Channel Voltage Dependence, Not Ca2+ Selectivity, Drives Pacemaker Activity and Amplifies Bursts in Nigral Dopamine Neurons

(2009) I. Putzier et al.   JOURNAL OF NEUROSCIENCE

Single Nigrostriatal Dopaminergic Neurons Form Widely Spread and Highly Dense Axonal Arborizations in the Neostriatum

(2009) W. Matsuda et al.   JOURNAL OF NEUROSCIENCE

Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria

(2009) Dennis W Dickson et al.   LANCET NEUROLOGY

Lesions outside the CNS in Parkinson's disease

(2009) Ruth Djaldetti et al.   MOVEMENT DISORDERS

Interplay between Cytosolic Dopamine, Calcium, and α-Synuclein Causes Selective Death of Substantia Nigra Neurons

(2009) Eugene V. Mosharov et al.   NEURON

Clinical availability of skin biopsy in the diagnosis of Parkinson's disease

(2009) Yasuo Miki et al.   NEUROSCIENCE LETTERS

Controversies over the staging of α-synuclein pathology in Parkinson’s disease

(2008) Michail E. Kalaitzakis et al.   ACTA NEUROPATHOLOGICA

A not entirely benign procedure: progression of Parkinson’s disease

(2008) Kelly Del Tredici et al.   ACTA NEUROPATHOLOGICA

A critical evaluation of current staging of α-synuclein pathology in Lewy body disorders

(2008) Kurt A. Jellinger   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The role of autophagy-lysosome pathway in neurodegeneration associated with Parkinson's disease

(2008) T. Pan et al.   BRAIN

Neuronal pigmented autophagic vacuoles: lipofuscin, neuromelanin, and ceroid as macroautophagic responses during aging and disease

(2008) David Sulzer et al.   JOURNAL OF NEUROCHEMISTRY

Dopaminergic midbrain neurons are the prime target for mitochondrial DNA deletions

(2008) A. Bender et al.   JOURNAL OF NEUROLOGY

Unregulated Cytosolic Dopamine Causes Neurodegeneration Associated with Oxidative Stress in Mice

(2008) L. Chen et al.   JOURNAL OF NEUROSCIENCE

Mitochondria in the aetiology and pathogenesis of Parkinson's disease

(2008) Anthony HV Schapira   LANCET NEUROLOGY

Anatomy, physiology, and pathophysiology of the pedunculopontine nucleus

(2008) Ned Jenkinson et al.   MOVEMENT DISORDERS

Gender-related changes in increase of dopaminergic neurons in the olfactory bulb of Parkinson's disease patients

(2008) Evelien Huisman et al.   MOVEMENT DISORDERS

Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease

(2008) Jeffrey H Kordower et al.   NATURE MEDICINE

Use of antihypertensives and the risk of Parkinson disease

(2008) C. Becker et al.   NEUROLOGY