Lewy pathology and neurodegeneration in premotor Parkinson's disease

Neuropathology underlying clinical variability in patients with synucleinopathies

(2011) Glenda M. Halliday et al.   ACTA NEUROPATHOLOGICA

Pale Neurites, Premature α-Synuclein Aggregates with Centripetal Extension from Axon Collaterals

(2011) Toshiro Kanazawa et al.   BRAIN PATHOLOGY

α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells

(2011) Christian Hansen et al.   JOURNAL OF CLINICAL INVESTIGATION

Peripheral Lewy body pathology in Parkinson's disease and incidental Lewy body disease: Four cases

(2011) Kelly Del Tredici et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

A critical appraisal of the premotor symptoms of Parkinson's disease: Potential usefulness in early diagnosis and design of neuroprotective trials

(2011) Anthony E. Lang   MOVEMENT DISORDERS

Milestones in Parkinson's disease-Clinical and pathologic features

(2011) Glenda Halliday et al.   MOVEMENT DISORDERS

Alpha-synuclein in colonic submucosa in early untreated Parkinson's disease

(2011) Kathleen M. Shannon et al.   MOVEMENT DISORDERS

A comparison between rectal and colonic biopsies to detect Lewy pathology in Parkinson's disease

(2011) Hélène Pouclet et al.   NEUROBIOLOGY OF DISEASE

Unmyelinated axons are more vulnerable to degeneration than myelinated axons of the cardiac nerve in Parkinson's disease

(2011) S. Orimo et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Can Parkinson's disease pathology be propagated from one neuron to another?

(2011) Christopher J.R. Dunning et al.   PROGRESS IN NEUROBIOLOGY

Cell type specific sequestration of choline acetyltransferase and tyrosine hydroxylase within Lewy bodies

(2010) Brittany N. Dugger et al.   ACTA NEUROPATHOLOGICA

Multi-organ distribution of phosphorylated α-synuclein histopathology in subjects with Lewy body disorders

(2010) Thomas G. Beach et al.   ACTA NEUROPATHOLOGICA

Lewy pathology in the submandibular gland of individuals with incidental Lewy body disease and sporadic Parkinson’s disease

(2010) Kelly Del Tredici et al.   ACTA NEUROPATHOLOGICA

Pain and death: Neurodegenerative disease mechanisms in the nociceptor

(2010) David B. Reichling et al.   ANNALS OF NEUROLOGY

Relationships between age and late progression of Parkinson's disease: a clinico-pathological study

(2010) P. A. Kempster et al.   BRAIN

Clinostatic Hypertension and Orthostatic Hypotension

(2010) Alfonso Lagi et al.   CLINICAL CARDIOLOGY

Direct Transfer of α-Synuclein from Neuron to Astroglia Causes Inflammatory Responses in Synucleinopathies

(2010) He-Jin Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nerve cells immunoreactive for p62 in select hypothalamic and brainstem nuclei of controls and Parkinson’s disease cases

(2010) Heiko Braak et al.   JOURNAL OF NEURAL TRANSMISSION

Premotor Parkinson's disease: Clinical features and detection strategies

(2010) Randolph Stephenson et al.   MOVEMENT DISORDERS

When does Parkinson's disease begin?

(2010) Carles Gaig et al.   MOVEMENT DISORDERS

Parkinson's at risk syndrome: Can Parkinson's disease be predicted?

(2010) Matthew B. Stern et al.   MOVEMENT DISORDERS

What are the most important nonmotor symptoms in patients with Parkinson's disease and are we missing them?

(2010) David A. Gallagher et al.   MOVEMENT DISORDERS

Evidence in favor of Braak staging of Parkinson's disease

(2010) Dennis W. Dickson et al.   MOVEMENT DISORDERS

Clinical subtypes of Parkinson's disease

(2010) Stephanie M. van Rooden et al.   MOVEMENT DISORDERS

Incidental Lewy body disease: Clinical comparison to a control cohort

(2010) Charles H. Adler et al.   MOVEMENT DISORDERS

Brain stem pathology in Parkinson's disease: An evaluation of the Braak staging model

(2010) Ann E. Kingsbury et al.   MOVEMENT DISORDERS

Exploring the electrocardiogram as a potential tool to screen for premotor Parkinson's disease

(2010) Ruksana Azhu Valappil et al.   MOVEMENT DISORDERS

Cardiac autonomic dysfunction in idiopathic REM sleep behavior disorder

(2010) Ronald B. Postuma et al.   MOVEMENT DISORDERS

Pain in Parkinson's disease

(2010) Blair Ford   MOVEMENT DISORDERS

Cell-to-cell transmission of non-prion protein aggregates

(2010) Seung-Jae Lee et al.   Nature Reviews Neurology

Progression of Parkinson's Disease Pathology Is Reproduced by Intragastric Administration of Rotenone in Mice

(2010) Francisco Pan-Montojo et al.   PLoS One

The propagation of prion-like protein inclusions in neurodegenerative diseases

(2010) Michel Goedert et al.   TRENDS IN NEUROSCIENCES

Diminished tyrosine hydroxylase immunoreactivity in the cardiac conduction system and myocardium in Parkinson’s disease: an anatomical study

(2009) Estifanos Ghebremedhin et al.   ACTA NEUROPATHOLOGICA

The ubiquitin proteasome system in neuropathology

(2009) Norman L. Lehman   ACTA NEUROPATHOLOGICA

Unified staging system for Lewy body disorders: correlation with nigrostriatal degeneration, cognitive impairment and motor dysfunction

(2009) Thomas G. Beach et al.   ACTA NEUROPATHOLOGICA

Pain and Its Relationship to Depression in Parkinson Disease

(2009) Uwe Ehrt et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Comparison of Risk Factor Profiles in Incidental Lewy Body Disease and Parkinson Disease

(2009) Roberta Frigerio et al.   ARCHIVES OF NEUROLOGY

Hyposialorrhea as an early manifestation of Parkinson disease

(2009) M.G. Cersósimo et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Beyond tremor and rigidity: non-motor features of Parkinson’s disease

(2009) Matthias Löhle et al.   JOURNAL OF NEURAL TRANSMISSION

Patterns of motor and non-motor features in Parkinson's disease

(2009) S M van Rooden et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Lewy Body Pathology in Normal Elderly Subjects

(2009) William R. Markesbery et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Parkinson's disease: Before the motor symptoms and beyond

(2009) Amos D. Korczyn et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Gastrointestinal dysfunction in Parkinson's Disease

(2009) Wolfgang H. Jost   JOURNAL OF THE NEUROLOGICAL SCIENCES

Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria

(2009) Dennis W Dickson et al.   LANCET NEUROLOGY

Incidental Lewy body disease restricted to the heart and stellate ganglia

(2009) Yasuo Miki et al.   MOVEMENT DISORDERS

Dysautonomia rating scales in Parkinson's disease: Sialorrhea, dysphagia, and constipation-Critique and recommendations by movement disorders task force on rating scales for Parkinson's disease

(2009) Marian L. Evatt et al.   MOVEMENT DISORDERS

Idiopathic REM sleep behavior disorder in the transition to degenerative disease

(2009) Ronald B. Postuma et al.   MOVEMENT DISORDERS

Loss of nocturnal blood pressure fall in various extrapyramidal syndromes

(2009) Claudia Schmidt et al.   MOVEMENT DISORDERS

Pain in Parkinson disease: the hidden epidemic

(2009) Blair Ford   Nature Reviews Neurology

The locus coeruleus and noradrenergic modulation of cognition

(2009) Susan J. Sara   NATURE REVIEWS NEUROSCIENCE

Incidental Lewy body disease: Do some cases represent a preclinical stage of dementia with Lewy bodies?

(2009) Roberta Frigerio et al.   NEUROBIOLOGY OF AGING

Chronic rotenone exposure reproduces Parkinson's disease gastrointestinal neuropathology

(2009) Robert E. Drolet et al.   NEUROBIOLOGY OF DISEASE

Medical records documentation of constipation preceding Parkinson disease: A case-control study

(2009) R. Savica et al.   NEUROLOGY

The locus ceruleus norepinephrine system: Functional organization and potential clinical significance

(2009) E. E. Benarroch   NEUROLOGY

Neuropathology of non-motor features of Parkinson disease

(2009) Dennis W. Dickson et al.   PARKINSONISM & RELATED DISORDERS

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of  -synuclein

(2009) P. Desplats et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly pathogenic H5N1 influenza virus can enter the central nervous system and induce neuroinflammation and neurodegeneration

(2009) H. Jang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Olfactory bulb α-synucleinopathy has high specificity and sensitivity for Lewy body disorders

(2008) Thomas G. Beach et al.   ACTA NEUROPATHOLOGICA

Evidence that incidental Lewy body disease is pre-symptomatic Parkinson’s disease

(2008) Dennis W. Dickson et al.   ACTA NEUROPATHOLOGICA

The progression of pathology in longitudinally followed patients with Parkinson’s disease

(2008) Glenda Halliday et al.   ACTA NEUROPATHOLOGICA

The olfactory vector hypothesis of neurodegenerative disease: Is it viable?

(2008) Richard L. Doty   ANNALS OF NEUROLOGY

Incidental Lewy Body Disease and Preclinical Parkinson Disease

(2008) Anthony DelleDonne et al.   ARCHIVES OF NEUROLOGY

Pain as a Nonmotor Symptom of Parkinson Disease

(2008) Giovanni Defazio et al.   ARCHIVES OF NEUROLOGY

The role of autophagy-lysosome pathway in neurodegeneration associated with Parkinson's disease

(2008) T. Pan et al.   BRAIN

Functional Neuroanatomy of the Noradrenergic Locus Coeruleus: Its Roles in the Regulation of Arousal and Autonomic Function Part I: Principles of Functional Organisation

(2008) E. Samuels et al.   Current Neuropharmacology

Depressive symptoms in Parkinson’s disease

(2008) M. R. Lemke   EUROPEAN JOURNAL OF NEUROLOGY

Non-motor symptoms in Parkinson’s disease

(2008) W. Poewe   EUROPEAN JOURNAL OF NEUROLOGY

Neuronal pigmented autophagic vacuoles: lipofuscin, neuromelanin, and ceroid as macroautophagic responses during aging and disease

(2008) David Sulzer et al.   JOURNAL OF NEUROCHEMISTRY

Lewy Body Pathology Involves Cutaneous Nerves

(2008) Masako Ikemura et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Incidence and Extent of Lewy Body-Related α-Synucleinopathy in Aging Human Olfactory Bulb

(2008) Renpei Sengoku et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Cardiac sympathetic denervation correlates with clinical and pathologic stages of Parkinson's disease

(2008) Hiroshige Fujishiro et al.   MOVEMENT DISORDERS

Neural control of the gastrointestinal tract: Implications for Parkinson disease

(2008) Maria G. Cersosimo et al.   MOVEMENT DISORDERS

A stable proportion of Lewy body bearing neurons in the substantia nigra suggests a model in which the Lewy body causes neuronal death

(2008) Sandrine Greffard et al.   NEUROBIOLOGY OF AGING

Alpha-synuclein-immunopositive myenteric neurons and vagal preganglionic terminals: Autonomic pathway implicated in Parkinson's disease?

(2008) R.J. Phillips et al.   NEUROSCIENCE

Association of olfactory dysfunction with risk for future Parkinson's disease

(2007) G. Webster Ross et al.   ANNALS OF NEUROLOGY

Axonal  -synuclein aggregates herald centripetal degeneration of cardiac sympathetic nerve in Parkinson's disease

(2007) S. Orimo et al.   BRAIN

Human-based studies on α-synuclein deposition and relationship to Parkinson's disease symptoms

(2007) Glenda M. Halliday et al.   EXPERIMENTAL NEUROLOGY

Nonmotor symptoms as presenting complaints in Parkinson's disease: A clinicopathological study

(2007) Sean S. O'Sullivan et al.   MOVEMENT DISORDERS