Monomeric ß-amyloid interacts with type-1 insulin-like growth factor receptors to provide energy supply to neurons

Metabolic Reserve as a Determinant of Cognitive Aging

(2018) Alexis M. Stranahan et al.   JOURNAL OF ALZHEIMERS DISEASE

A critique of the drug discovery and phase 3 clinical programs targeting the amyloid hypothesis for Alzheimer disease

(2014) Eric Karran et al.   ANNALS OF NEUROLOGY

Alzheimer’s Disease and Type 2 Diabetes: Multiple Mechanisms Contribute to Interactions

(2014) Anusha Jayaraman et al.   Current Diabetes Reports

Allosteric targeting of receptor tyrosine kinases

(2014) Frederik De Smet et al.   NATURE BIOTECHNOLOGY

Glycolysis and Oxidative Phosphorylation in Neurons and Astrocytes during Network Activity in Hippocampal Slices

(2013) Anton I Ivanov et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Alternations of central insulin-like growth factor-1 sensitivity in APP/PS1 transgenic mice and neuronal models

(2013) Bing Zhang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline

(2012) Konrad Talbot et al.   JOURNAL OF CLINICAL INVESTIGATION

Aβ1-15/16 as a Potential Diagnostic Marker in Neurodegenerative Diseases

(2012) Magdalena Nutu et al.   NEUROMOLECULAR MEDICINE

Age-related increase in amyloid plaque burden is associated with impairment in conditioned fear memory in CRND8 mouse model of amyloidosis

(2012) Amanda Hanna et al.   Alzheimers Research & Therapy

Nature of the Amyloid-β Monomer and the Monomer-Oligomer Equilibrium

(2011) Suman Nag et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impaired  -Amyloid Secretion in Alzheimer's Disease Pathogenesis

(2011) D. Tampellini et al.   JOURNAL OF NEUROSCIENCE

Resolving controversies on the path to Alzheimer's therapeutics

(2011) Dennis J Selkoe   NATURE MEDICINE

IGF-I and the aging mammalian brain

(2010) J. Piriz et al.   EXPERIMENTAL GERONTOLOGY

Cognitive effects of cell-derived and synthetically derived Aβ oligomers

(2010) Miranda N. Reed et al.   NEUROBIOLOGY OF AGING

Insulin Receptor Isoforms and Insulin Receptor/Insulin-Like Growth Factor Receptor Hybrids in Physiology and Disease

(2009) Antonino Belfiore et al.   ENDOCRINE REVIEWS

 -Amyloid Monomers Are Neuroprotective

(2009) M. L. Giuffrida et al.   JOURNAL OF NEUROSCIENCE

The facilitative glucose transporter GLUT3: 20 years of distinction

(2008) Ian A. Simpson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Correlating Cerebral Hypometabolism With Future Memory Decline in Subsequent Converters to Amnestic Pre–Mild Cognitive Impairment

(2008) Richard J. Caselli et al.   ARCHIVES OF NEUROLOGY

The Autistic Neuron: Troubled Translation?

(2008) Raymond J. Kelleher et al.   CELL

Amyloid beta oligomers induce impairment of neuronal insulin receptors

(2007) Wei-Qin Zhao et al.   FASEB JOURNAL