Changes in lipid membranes may trigger amyloid toxicity in Alzheimer's disease

Amyloid-β peptide protects against microbial infection in mouse and worm models of Alzheimer’s disease

(2016) Deepak Kumar Vijaya Kumar et al.   Science Translational Medicine

Atomic force microscopy to study molecular mechanisms of amyloid fibril formation and toxicity in Alzheimer’s disease

(2014) Elizabeth Drolle et al.   DRUG METABOLISM REVIEWS

Plasma phospholipids identify antecedent memory impairment in older adults

(2014) Mark Mapstone et al.   NATURE MEDICINE

Neural compensation in older people with brain amyloid-β deposition

(2014) Jeremy A Elman et al.   NATURE NEUROSCIENCE

Langmuir Monolayers of Monocationic Lipid Mixed with Cholesterol or Fluorocholesterol: DNA Adsorption Studies

(2013) Diana Paiva et al.   LANGMUIR

Effects of membrane interaction and aggregation of amyloid β-peptide on lipid mobility and membrane domain structure

(2013) Kenji Sasahara et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Using neurolipidomics to identify phospholipid mediators of synaptic (dys)function in Alzheimer's Disease

(2013) Steffany A. L. Bennett et al.   Frontiers in Physiology

Biophysical Insights into How Surfaces, Including Lipid Membranes, Modulate Protein Aggregation Related to Neurodegeneration

(2013) Kathleen A. Burke et al.   Frontiers in Neurology

Nanoscale Electrostatic Domains in Cholesterol-Laden Lipid Membranes Create a Target for Amyloid Binding

(2012) Elizabeth Drolle et al.   BIOPHYSICAL JOURNAL

Atomic Force Microscopy and MD Simulations Reveal Pore-Like Structures of All-d-Enantiomer of Alzheimer’s β-Amyloid Peptide: Relevance to the Ion Channel Mechanism of AD Pathology

(2012) Laura Connelly et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons

(2012) Ji Won Um et al.   NATURE NEUROSCIENCE

Alzheimer Aβ peptide interactions with lipid membranes

(2012) Florentina Tofoleanu et al.   Prion

Membrane cholesterol content plays a key role in the neurotoxicity of β-amyloid: implications for Alzheimer’s disease

(2011) Andrey Y. Abramov et al.   AGING CELL

Aβ42 oligomers, but not fibrils, simultaneously bind to and cause damage to ganglioside-containing lipid membranes

(2011) Thomas L. Williams et al.   BIOCHEMICAL JOURNAL

Antimicrobial Protegrin-1 Forms Amyloid-Like Fibrils with Rapid Kinetics Suggesting a Functional Link

(2011) Hyunbum Jang et al.   BIOPHYSICAL JOURNAL

Pathological significance of ganglioside clusters in Alzheimer’s disease

(2011) Katsuhiko Yanagisawa   JOURNAL OF NEUROCHEMISTRY

Effect of Surfaces on Amyloid Fibril Formation

(2011) Bradley Moores et al.   PLoS One

Lipid Membranes and β-Amyloid: A Harmful Connection

(2010) G.P. Eckert et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Molecular insights into amyloid regulation by membrane cholesterol and sphingolipids: common mechanisms in neurodegenerative diseases

(2010) Jacques Fantini et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Membrane Lipids, Selectively Diminished in Alzheimer Brains, Suggest Synapse Loss as a Primary Event in Early-Onset Form (Type I) and Demyelination in Late-Onset Form (Type II)

(2010) Lars Svennerholm et al.   JOURNAL OF NEUROCHEMISTRY

The Alzheimer's Disease-Associated Amyloid β-Protein Is an Antimicrobial Peptide

(2010) Stephanie J. Soscia et al.   PLoS One

Lipid Rafts As a Membrane-Organizing Principle

(2010) D. Lingwood et al.   SCIENCE

Kelvin probe force microscopy in application to biomolecular films: Frequency modulation, amplitude modulation, and lift mode

(2010) Brad Moores et al.   ULTRAMICROSCOPY

Role of gangliosides in brain aging and neurodegeneration

(2010) Kristina Mlinac et al.   Translational Neuroscience

Cholesterol Modulates the Interaction of β-Amyloid Peptide with Lipid Bilayers

(2009) Liming Qiu et al.   BIOPHYSICAL JOURNAL

Thematic Review Series: Sphingolipids.Role of ganglioside metabolism in the pathogenesis of Alzheimer's disease—a review,

(2008) Toshio Ariga et al.   JOURNAL OF LIPID RESEARCH

Amyloid Aggregation on Lipid Bilayers and Its Impact on Membrane Permeability

(2008) Ran Friedman et al.   JOURNAL OF MOLECULAR BIOLOGY

Deregulation of sphingolipid metabolism in Alzheimer's disease

(2008) Xingxuan He et al.   NEUROBIOLOGY OF AGING

Using model membranes for the study of amyloid beta:lipid interactions and neurotoxicity

(2007) Mun'delanji Vestergaard et al.   BIOTECHNOLOGY AND BIOENGINEERING