Regulation of xanthine dehydrogensase gene expression and uric acid production in human airway epithelial cells

Impaired Antiviral Stress Granule and IFN-β Enhanceosome Formation Enhances Susceptibility to Influenza Infection in Chronic Obstructive Pulmonary Disease Epithelium

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Chronic inflammatory airway diseases: the central role of the epithelium revisited

(2016) S. T. Gohy et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Respiratory Syncytial Virus Infection Triggers Epithelial HMGB1 Release as a Damage-Associated Molecular Pattern Promoting a Monocytic Inflammatory Response

(2016) Yashoda M. Hosakote et al.   JOURNAL OF VIROLOGY

Animal models of COPD: What do they tell us?

(2016) Bernadette Jones et al.   RESPIROLOGY

A novel microbe-based treatment that attenuates the inflammatory profile in a mouse model of allergic airway disease

(2016) Mark Bazett et al.   Scientific Reports

Comprehensive metabolomics identifies the alarmin uric acid as a critical signal for the induction of peanut allergy

(2015) J. Kong et al.   ALLERGY

Targeting PI3K-p110α Suppresses Influenza Virus Infection in Chronic Obstructive Pulmonary Disease

(2015) Alan Chen-Yu Hsu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Nucleotide-Binding Domain, Leucine-Rich Repeat Protein 3 Inflammasome/IL-1 Receptor I Axis Mediates Innate, but Not Adaptive, Immune Responses after Exposure to Particulate Matter under 10 μm

(2015) Jeremy A. Hirota et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The innate immune function of airway epithelial cells in inflammatory lung disease

(2015) Pieter S. Hiemstra et al.   EUROPEAN RESPIRATORY JOURNAL

Urban particulate matter increases human airway epithelial cell IL-1β secretion following scratch wounding and H1N1 influenza A exposurein vitro

(2015) Jeremy A. Hirota et al.   EXPERIMENTAL LUNG RESEARCH

Barrier Epithelial Cells and the Control of Type 2 Immunity

(2015) Hamida Hammad et al.   IMMUNITY

The Contribution of the Airway Epithelial Cell to Host Defense

(2015) Frauke Stanke   MEDIATORS OF INFLAMMATION

A pathogenic role for tumor necrosis factor-related apoptosis-inducing ligand in chronic obstructive pulmonary disease

(2015) T J Haw et al.   Mucosal Immunology

Mucosal production of uric acid by airway epithelial cells contributes to particulate matter-induced allergic sensitization

(2015) M J Gold et al.   Mucosal Immunology

Importance of Mast Cell Prss31/Transmembrane Tryptase/Tryptase-γ in Lung Function and Experimental Chronic Obstructive Pulmonary Disease and Colitis

(2014) Philip M. Hansbro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation

(2014) Bernardo S Franklin et al.   NATURE IMMUNOLOGY

PM10-stimulated airway epithelial cells activate primary human dendritic cells independent of uric acid: Application of anin vitromodel system exposing dendritic cells to airway epithelial cell-conditioned media

(2014) Jeremy A. Hirota et al.   RESPIROLOGY

Transcription of Interleukin-25 and Extracellular Release of the Protein Is Regulated by Allergen Proteases in Airway Epithelial Cells

(2013) Hideaki Kouzaki et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis

(2013) Emma L. Beckett et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Rhinovirus-induced interferon production is not deficient in well controlled asthma

(2013) Annemarie Sykes et al.   THORAX

Airway gene expression in COPD is dynamic with inhaled corticosteroid treatment and reflects biological pathways associated with disease activity

(2013) Maarten van den Berge et al.   THORAX

Human airway epithelial cell innate immunity: relevance to asthma

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The airway epithelium nucleotide-binding domain and leucine-rich repeat protein 3 inflammasome is activated by urban particulate matter

(2012) Jeremy A. Hirota et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Uric acid as a danger signal in gout and its comorbidities

(2012) Kenneth L. Rock et al.   Nature Reviews Rheumatology

Critical Role of Constitutive Type I Interferon Response in Bronchial Epithelial Cell to Influenza Infection

(2012) Alan C-Y. Hsu et al.   PLoS One

TLR2, but Not TLR4, Is Required for Effective Host Defence against Chlamydia Respiratory Tract Infection in Early Life

(2012) Emma L. Beckett et al.   PLoS One

Innate Immunity in the Respiratory Epithelium

(2011) Dane Parker et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Cyclic Nucleotide Compartmentalization: Contributions of Phosphodiesterases and ATP-Binding Cassette Transporters

(2011) Satish Cheepala et al.   Annual Review of Pharmacology and Toxicology

An Unexpected Role for Uric Acid as an Inducer of T Helper 2 Cell Immunity to Inhaled Antigens and Inflammatory Mediator of Allergic Asthma

(2011) Mirjam Kool et al.   IMMUNITY

Defective epithelial barrier function in asthma

(2011) Chang Xiao et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The Danger Signal, Extracellular ATP, Is a Sensor for an Airborne Allergen and Triggers IL-33 Release and Innate Th2-Type Responses

(2011) Hideaki Kouzaki et al.   JOURNAL OF IMMUNOLOGY

Inflammatory Stimuli Inhibit Glucocorticoid-Dependent Transactivation in Human Pulmonary Epithelial Cells: Rescue by Long-Acting  2-Adrenoceptor Agonists

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The role of interleukin-4Rα in the induction of glutamic acid decarboxylase in airway epithelium following acute house dust mite exposure

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A Large-Scale, Consortium-Based Genomewide Association Study of Asthma

(2010) Miriam F. Moffatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Airway Mucus Function and Dysfunction

(2010) John V. Fahy et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Inflammasomes: Guardians of the Body

(2009) Fabio Martinon et al.   Annual Review of Immunology

Cigarette smoke modulates rhinovirus-induced airway epithelial cell chemokine production

(2009) M. H. Hudy et al.   EUROPEAN RESPIRATORY JOURNAL

Monosodium urate crystals in inflammation and immunity

(2009) Yan Shi et al.   IMMUNOLOGICAL REVIEWS

Selection of housekeeping genes for real-time PCR in atopic human bronchial epithelial cells

(2008) J-Q. He et al.   EUROPEAN RESPIRATORY JOURNAL

Receptor-Independent, Direct Membrane Binding Leads to Cell-Surface Lipid Sorting and Syk Kinase Activation in Dendritic Cells

(2008) Gilbert Ng et al.   IMMUNITY

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

The IL-1-Like Cytokine IL-33 Is Constitutively Expressed in the Nucleus of Endothelial Cells and Epithelial Cells In Vivo: A Novel ‘Alarmin’?

(2008) Christine Moussion et al.   PLoS One