Pancreatic cancer cell/fibroblast co-culture induces M2 like macrophages that influence therapeutic response in a 3D model

Current progress in immunotherapy for pancreatic cancer

(2016) Kelly Foley et al.   CANCER LETTERS

Infiltration of lymphocyte subpopulations into cancer microtissues as a tool for the exploration of immunomodulatory agents and biomarkers

(2016) Stefan Koeck et al.   IMMUNOBIOLOGY

The Landscape of Pancreatic Cancer Therapeutic Resistance Mechanisms

(2016) Saswati Chand et al.   International Journal of Biological Sciences

From bench to bedside a comprehensive review of pancreatic cancer immunotherapy

(2016) Paul R. Kunk et al.   Journal for ImmunoTherapy of Cancer

The inflammatory milieu within the pancreatic cancer microenvironment correlates with clinicopathologic parameters, chemoresistance and survival

(2015) Daniel Delitto et al.   BMC CANCER

Abstract 319: Comparison of 2D- and 3D-culture models as drug-testing platforms in breast cancer

(2015) Yoshinori Imamura et al.   CANCER RESEARCH

Induction of T-cell Immunity Overcomes Complete Resistance to PD-1 and CTLA-4 Blockade and Improves Survival in Pancreatic Carcinoma

(2015) R. Winograd et al.   Cancer Immunology Research

Fibroblasts Influence Survival and Therapeutic Response in a 3D Co-Culture Model

(2015) Meher Majety et al.   PLoS One

Targeting Tumor-Associated Macrophages with Anti-CSF-1R Antibody Reveals a Strategy for Cancer Therapy

(2014) Carola H. Ries et al.   CANCER CELL

Tumor-Associated Macrophages: From Mechanisms to Therapy

(2014) Roy Noy et al.   IMMUNITY

Tumor-associated macrophages exhibit pro- and anti-inflammatory properties by which they impact on pancreatic tumorigenesis

(2014) Ole Helm et al.   INTERNATIONAL JOURNAL OF CANCER

Complex role for the immune system in initiation and progression of pancreatic cancer

(2014) Kristin S Inman   WORLD JOURNAL OF GASTROENTEROLOGY

Functions of Arginase Isoforms in Macrophage Inflammatory Responses: Impact on Cardiovascular Diseases and Metabolic Disorders

(2014) Zhihong Yang et al.   Frontiers in Immunology

Tumor-Associated Macrophages as Major Players in the Tumor Microenvironment

(2014) Theerawut Chanmee et al.   Cancers

Impact of tumour associated macrophages in pancreatic cancer

(2013) Ainhoa Mielgo et al.   BMB Reports

CD137 as a Biomarker for Tumor-Reactive T Cells: Finding Gold in the Desert

(2013) Y. Zhu et al.   CLINICAL CANCER RESEARCH

PD1 (CD279) and PD-L1 (CD274, B7H1) expression in primary central nervous system lymphomas (PCNSL)

(2013) Anna Sophie Berghoff et al.   CLINICAL NEUROPATHOLOGY

A three-dimensional microenvironment alters protein expression and chemosensitivity of epithelial ovarian cancer cells in vitro

(2013) Janet Myungjin Lee et al.   LABORATORY INVESTIGATION

Macrophages mediate gemcitabine resistance of pancreatic adenocarcinoma by upregulating cytidine deaminase

(2013) N Weizman et al.   ONCOGENE

Application of Concave Microwells to Pancreatic Tumor Spheroids Enabling Anticancer Drug Evaluation in a Clinically Relevant Drug Resistance Model

(2013) Sang-Eun Yeon et al.   PLoS One

Immune infiltrates as predictive markers of survival in pancreatic cancer patients

(2013) Maria Pia Protti et al.   Frontiers in Physiology

Tumor-Derived Granulocyte-Macrophage Colony-Stimulating Factor Regulates Myeloid Inflammation and T Cell Immunity in Pancreatic Cancer

(2012) Lauren J. Bayne et al.   CANCER CELL

The multicellular tumor spheroid model for high-throughput cancer drug discovery

(2012) Daniel V LaBarbera et al.   Expert Opinion on Drug Discovery

Tumor-Associated Macrophages Promote Invasion while Retaining Fc-Dependent Anti-Tumor Function

(2012) K. D. Grugan et al.   JOURNAL OF IMMUNOLOGY

Integrating Macrophages into Organotypic Co-Cultures: A 3D In Vitro Model to Study Tumor-Associated Macrophages

(2012) Nina Linde et al.   PLoS One

Differentiation and gene expression profile of tumor-associated macrophages

(2012) Astrid Schmieder et al.   SEMINARS IN CANCER BIOLOGY

Regulation of Macrophage Arginase Expression and Tumor Growth by the Ron Receptor Tyrosine Kinase

(2011) D. R. Sharda et al.   JOURNAL OF IMMUNOLOGY

Identification and manipulation of tumor associated macrophages in human cancers

(2011) Moniek Heusinkveld et al.   Journal of Translational Medicine

CD40 Agonists Alter Tumor Stroma and Show Efficacy Against Pancreatic Carcinoma in Mice and Humans

(2011) G. L. Beatty et al.   SCIENCE

3D tumour models: novel in vitro approaches to cancer studies

(2011) Agata Nyga et al.   Journal of Cell Communication and Signaling

Different Tumor Microenvironments Contain Functionally Distinct Subsets of Macrophages Derived from Ly6C(high) Monocytes

(2010) K. Movahedi et al.   CANCER RESEARCH

Significance of M2-Polarized Tumor-Associated Macrophage in Pancreatic Cancer

(2009) Hiroshi Kurahara et al.   JOURNAL OF SURGICAL RESEARCH

Pancreatic Cancer

(2008) Anirban Maitra et al.   Annual Review of Pathology-Mechanisms of Disease

Macrophage activation and polarization

(2007) Fernando Oneissi Martinez   Frontiers in Bioscience-Landmark