Neuronal Cell Death and Degeneration through Increased Nitroxidative Stress and Tau Phosphorylation in HIV-1 Transgenic Rats

Cytochrome P450-2E1 promotes aging-related hepatic steatosis, apoptosis and fibrosis through increased nitroxidative stress

(2016) Mohamed A. Abdelmegeed et al.   FREE RADICAL BIOLOGY AND MEDICINE

Tau and Aβ imaging, CSF measures, and cognition in Alzheimer’s disease

(2016) Matthew R. Brier et al.   Science Translational Medicine

Compromised MAPK signaling in human diseases: an update

(2015) Eun Kyung Kim et al.   ARCHIVES OF TOXICOLOGY

Low-dose aspirin (acetylsalicylate) prevents increases in brain PGE2, 15-epi-lipoxin A4 and 8-isoprostane concentrations in 9 month-old HIV-1 transgenic rats, a model for HIV-1 associated neurocognitive disorders

(2015) Helene C. Blanchard et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Critical role of c-jun N-terminal protein kinase in promoting mitochondrial dysfunction and acute liver injury

(2015) Sehwan Jang et al.   Redox Biology

Binge alcohol promotes hypoxic liver injury through a CYP2E1–HIF-1α-dependent apoptosis pathway in mice and humans

(2014) Jun-Won Yun et al.   FREE RADICAL BIOLOGY AND MEDICINE

HIV-1 transcriptional regulation in the central nervous system and implications for HIV cure research

(2014) Melissa J. Churchill et al.   JOURNAL OF NEUROVIROLOGY

The role of tau protein in HIV-associated neurocognitive disorders

(2014) Lecia AM Brown et al.   Molecular Neurodegeneration

Functional Roles of Protein Nitration in Acute and Chronic Liver Diseases

(2014) Mohamed A. Abdelmegeed et al.   Oxidative Medicine and Cellular Longevity

Mitochondrial dysfunction and tissue injury by alcohol, high fat, nonalcoholic substances and pathological conditions through post-translational protein modifications

(2014) Byoung-Joon Song et al.   Redox Biology

Activating the Nrf2-mediated antioxidant response element restores barrier function in the alveolar epithelium of HIV-1 transgenic rats

(2013) Xian Fan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Hypersensitivity of the hippocampal CA3 region to stress-induced neurodegeneration and amyloidogenesis in a rat model of surgical menopause

(2013) Quan-guang Zhang et al.   BRAIN

Update on HIV-Associated Neurocognitive Disorders

(2013) Tariq B. Alfahad et al.   Current Neurology and Neuroscience Reports

Nitration of Hsp90 induces cell death

(2013) M. C. Franco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIV gp120- and methamphetamine-mediated oxidative stress induces astrocyte apoptosis via cytochrome P450 2E1

(2013) A Shah et al.   Cell Death & Disease

Cognitive impairment in HIV infection is associated with MRI and CSF pattern of neurodegeneration

(2012) F. Steinbrink et al.   EUROPEAN JOURNAL OF NEUROLOGY

The prevalence of cirrhosis and hepatocellular carcinoma in patients with human immunodeficiency virus infection

(2012) George N. Ioannou et al.   HEPATOLOGY

Inhibition of Nuclear Factor Erythroid 2-Related Factor 2 Exacerbates HIV-1 gp120-Induced Oxidative and Inflammatory Response: Role in HIV Associated Neurocognitive Disorder

(2012) Pichili Vijaya Bhaskar Reddy et al.   NEUROCHEMICAL RESEARCH

Inflammation Induced by Infection Potentiates Tau Pathological Features in Transgenic Mice

(2011) Michael Sy et al.   AMERICAN JOURNAL OF PATHOLOGY

Increased CDK5 Expression in HIV Encephalitis Contributes to Neurodegeneration via Tau Phosphorylation and Is Reversed with Roscovitine

(2011) Christina Patrick et al.   AMERICAN JOURNAL OF PATHOLOGY

Direct evidence of phosphorylated neuronal intermediate filament proteins in neurofibrillary tangles (NFTs): phosphoproteomics of Alzheimer's NFTs

(2011) Parvathi Rudrabhatla et al.   FASEB JOURNAL

HIV-1 Tat neurotoxicity: A model of acute and chronic exposure, and neuroprotection by gene delivery of antioxidant enzymes

(2011) Lokesh Agrawal et al.   NEUROBIOLOGY OF DISEASE

Abnormal tau phosphorylation in primary progressive multiple sclerosis

(2010) Jane Marian Anderson et al.   ACTA NEUROPATHOLOGICA

Erythropoietin plus insulin-like growth factor-I protects against neuronal damage in a murine model of human immunodeficiency virus-associated neurocognitive disorders

(2010) Yeon-Joo Kang et al.   ANNALS OF NEUROLOGY

LPS- induced inflammation exacerbates phospho-tau pathology in rTg4510 mice

(2010) Daniel C Lee et al.   Journal of Neuroinflammation

Exposure to HIV-1 Directly Impairs Mucosal Epithelial Barrier Integrity Allowing Microbial Translocation

(2010) Aisha Nazli et al.   PLoS Pathogens

Inhibition of p66ShcA Longevity Gene Rescues Podocytes from HIV-1-induced Oxidative Stress and Apoptosis

(2009) Mohammad Husain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cocaine and human immunodeficiency virus type 1 gp120 mediate neurotoxicity through overlapping signaling pathways

(2009) Honghong Yao et al.   JOURNAL OF NEUROVIROLOGY

The role of tau in neurodegeneration

(2009) Tania F Gendron et al.   Molecular Neurodegeneration

Cerebrospinal tau, phospho-tau, and beta-amyloid and neuropsychological functions in Parkinson's disease

(2009) Yaroslau Compta et al.   MOVEMENT DISORDERS

Vascular risk factors, HIV serostatus, and cognitive dysfunction in gay and bisexual men

(2009) J. T. Becker et al.   NEUROLOGY

CSF biomarkers of Alzheimer disease in HIV-associated neurologic disease

(2009) D. B. Clifford et al.   NEUROLOGY

HIV-1 transgene expression in rats causes oxidant stress and alveolar epithelial barrier dysfunction

(2009) Coy Lassiter et al.   AIDS Research and Therapy

Vascular oxidative stress and nitric oxide depletion in HIV-1 transgenic rats are reversed by glutathione restoration

(2008) Erik R. Kline et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Enhanced Tau Phosphorylation in the Hippocampus of Mice Treated with 3,4-Methylenedioxymethamphetamine ("Ecstasy")

(2008) C. L. Busceti et al.   JOURNAL OF NEUROSCIENCE

Further characterization of the spatial learning deficit in the human immunodeficiency virus-1 transgenic rat

(2008) Abigail L Lashomb et al.   JOURNAL OF NEUROVIROLOGY

Phosphorylation of tau and α-synuclein in synaptic-enriched fractions of the frontal cortex in Alzheimer’s disease, and in Parkinson’s disease and related α-synucleinopathies

(2008) G. Muntané et al.   NEUROSCIENCE