Apigenin: Selective CK2 inhibitor increases Ikaros expression and improves T cell homeostasis and function in murine pancreatic cancer

Targeting casein kinase II restores Ikaros tumor suppressor activity and demonstrates therapeutic efficacy in high-risk leukemia

(2015) C. Song et al.   BLOOD

Murine Pancreatic Adenocarcinoma Reduces Ikaros Expression and Disrupts T Cell Homeostasis

(2015) Nadine Nelson et al.   PLoS One

Protein Phosphatase 1 (PP1) and Casein Kinase II (CK2) regulate Ikaros-mediated repression ofTdTin thymocytes and T-cell leukemia

(2014) Haijun Wang et al.   PEDIATRIC BLOOD & CANCER

CD4 T-cell Subsets and Tumor Immunity: The Helpful and the Not-so-Helpful

(2014) H.-J. Kim et al.   Cancer Immunology Research

Dendritic cell immunotherapy combined with gemcitabine chemotherapy enhances survival in a murine model of pancreatic carcinoma

(2013) Tomar Ghansah et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

A Novel, Non-canonical Splice Variant of the Ikaros Gene Is Aberrantly Expressed in B-cell Lymphoproliferative Disorders

(2013) Daria Capece et al.   PLoS One

Pancreatic cancer: why is it so hard to treat?

(2013) Paul E. Oberstein et al.   Therapeutic Advances in Gastroenterology

Overcoming immunosuppression as a new immunotherapeutic approach against pancreatic cancer

(2013) Alexandr V Bazhin et al.   OncoImmunology

Apigenin Induces Apoptosis and Blocks Growth of Medroxyprogesterone Acetate-Dependent BT-474 Xenograft Tumors

(2012) Benford Mafuvadze et al.   Hormones & Cancer

Ikaros, CK2 kinase, and the road to leukemia

(2011) Sinisa Dovat et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The Ikaros gene family: Transcriptional regulators of hematopoiesis and immunity

(2011) Liza B. John et al.   MOLECULAR IMMUNOLOGY

Circulating CD4+CD25+ Regulatory T Cells in Patients With Pancreatic Cancer

(2011) Tomohisa Yamamoto et al.   PANCREAS

Murine Pancreatic Adenocarcinoma Dampens SHIP-1 Expression and Alters MDSC Homeostasis and Function

(2011) Shari Pilon-Thomas et al.   PLoS One

Protein Kinase CK2 in Health and Disease

(2009) L. A. Pinna et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Countering tumor-induced immunosuppression during immunotherapy for pancreatic cancer

(2009) Michael A Morse et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Ikaros Stability and Pericentromeric Localization Are Regulated by Protein Phosphatase 1

(2009) Marcela Popescu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cutting Edge: Ikaros Null Thymocytes Mature into the CD4 Lineage with Reduced TCR Signal: A Study Using CD3  Immunoreceptor Tyrosine-Based Activation Motif Transgenic Mice

(2009) J. A. Urban et al.   JOURNAL OF IMMUNOLOGY

EGF-Induced ERK Activation Promotes CK2-Mediated Disassociation of α-Catenin from β-Catenin and Transactivation of β-Catenin

(2009) Haitao Ji et al.   MOLECULAR CELL

Proteasome inhibition represses ERα gene expression in ER+ cells: a new link between proteasome activity and estrogen signaling in breast cancer

(2009) G L Powers et al.   ONCOGENE

The Flavonoid Apigenin Potentiates the Growth Inhibitory Effects of Gemcitabine and Abrogates Gemcitabine Resistance in Human Pancreatic Cancer Cells

(2009) Matthew J. Strouch et al.   PANCREAS

Effects of proteasome inhibitor, MG132, on proteasome activity and oxidative status of rat liver

(2008) Albena Alexandrova et al.   CELL BIOCHEMISTRY AND FUNCTION

Multiple roles for CD4+T cells in anti-tumor immune responses

(2008) Richard Kennedy et al.   IMMUNOLOGICAL REVIEWS

Recruitment of Ikaros to Pericentromeric Heterochromatin Is Regulated by Phosphorylation

(2008) Zafer Gurel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gene targeting of CK2 catalytic subunits

(2008) David C. Seldin et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Too much of a good thing: The role of protein kinase CK2 in tumorigenesis and prospects for therapeutic inhibition of CK2

(2007) James S. Duncan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS