A Novel, Non-canonical Splice Variant of the Ikaros Gene Is Aberrantly Expressed in B-cell Lymphoproliferative Disorders
Published 2013 View Full Article
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Title
A Novel, Non-canonical Splice Variant of the Ikaros Gene Is Aberrantly Expressed in B-cell Lymphoproliferative Disorders
Authors
Keywords
Apoptosis, B cells, Lymphomas, Polymerase chain reaction, Cell proliferation, Myelodysplastic syndromes, Hyperexpression techniques, Acute lymphoblastic leukemia
Journal
PLoS One
Volume 8, Issue 7, Pages e68080
Publisher
Public Library of Science (PLoS)
Online
2013-07-10
DOI
10.1371/journal.pone.0068080
References
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Related references
Note: Only part of the references are listed.- Expression of dominant-negative Ikaros isoforms and associated genetic alterations in Chinese adult patients with leukemia
- (2012) Ping Liu et al. ANNALS OF HEMATOLOGY
- Ikaros is degraded by proteasome-dependent mechanism in the early phase of apoptosis induction
- (2011) Li-Cai He et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Expression of Ikaros Isoform 6 in Chinese Children With Acute Lymphoblastic Leukemia
- (2011) Fen Zhou et al. JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
- The Ikaros gene family: Transcriptional regulators of hematopoiesis and immunity
- (2011) Liza B. John et al. MOLECULAR IMMUNOLOGY
- Ikaros changes the face of NuRD remodeling
- (2011) Kenneth J Oestreich et al. NATURE IMMUNOLOGY
- Deregulation of Aiolos expression in chronic lymphocytic leukemia is associated with epigenetic modifications
- (2010) K. Billot et al. BLOOD
- Ikaros and Aiolos Inhibit Pre-B-Cell Proliferation by Directly Suppressing c-Myc Expression
- (2010) S. Ma et al. MOLECULAR AND CELLULAR BIOLOGY
- The tumor suppressor gene KCTD11REN is regulated by Sp1 and methylation and its expression is reduced in tumors
- (2010) M Michela Mancarelli et al. Molecular Cancer
- Pre–B cell receptor–mediated cell cycle arrest in Philadelphia chromosome–positive acute lymphoblastic leukemia requiresIKAROSfunction
- (2009) Daniel Trageser et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Deletion ofIKZF1and Prognosis in Acute Lymphoblastic Leukemia
- (2009) Charles G. Mullighan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Expression of spliced oncogenic Ikaros isoforms in Philadelphia-positive acute lymphoblastic leukemia patients treated with tyrosine kinase inhibitors: implications for a new mechanism of resistance
- (2008) I. Iacobucci et al. BLOOD
- Identification of different Ikaros cDNA transcripts in Philadelphia-positive adult acute lymphoblastic leukemia by a high-throughput capillary electrophoresis sizing method
- (2008) I. Iacobucci et al. HAEMATOLOGICA
- The Ikaros splice isoform, Ikaros 6, immortalizes murine haematopoietic progenitor cells
- (2008) Anna Ruiz et al. INTERNATIONAL JOURNAL OF CANCER
- Ikaros dominant negative isoform (Ik6) induces IL-3-independent survival of murine pro-B lymphocytes by activating JAK-STAT and up-regulating Bcl-xl levels
- (2008) Gen Kano et al. LEUKEMIA & LYMPHOMA
- BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros
- (2008) Charles G. Mullighan et al. NATURE
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