Capsaicin reduces Alzheimer-associated tau changes in the hippocampus of type 2 diabetes rats

Activation of TRPV1 channel by dietary capsaicin improves visceral fat remodeling through connexin43-mediated Ca2+ Influx

(2015) Jian Chen et al.   Cardiovascular Diabetology

Transient receptor potential vanilloid type-1 channel regulates diet-induced obesity, insulin resistance, and leptin resistance

(2015) Eunjung Lee et al.   FASEB JOURNAL

Exendin-4, a Glucagon-Like Peptide-1 Receptor Agonist, Reduces Alzheimer Disease-Associated Tau Hyperphosphorylation in the Hippocampus of Rats With Type 2 Diabetes

(2015) Weijie Xu et al.   JOURNAL OF INVESTIGATIVE MEDICINE

The case for rejecting the amyloid cascade hypothesis

(2015) Karl Herrup   NATURE NEUROSCIENCE

Red peppers with moderate and severe pungency prevent the memory deficit and hepatic insulin resistance in diabetic rats with Alzheimer’s disease

(2015) Hye Yang et al.   Nutrition & Metabolism

A novel syntheticPiperamide derivative NED-180 inhibits hyperpigmentation by activating the PI3K and ERK pathways and by regulating Ca2+influx via TRPM1 channels

(2015) Eunson Hwang et al.   Pigment Cell & Melanoma Research

Potential therapeutic value of TRPV1 and TRPA1 in diabetes mellitus and obesity

(2015) Andrei V. Derbenev et al.   Seminars in Immunopathology

Approaches to treatment 2: Comparison of American Association of Clinical Endocrinologists (AACE) and American Diabetes Association (ADA) type 2 diabetes treatment guidelines

(2015) Zachary T. Bloomgarden et al.   Journal of Diabetes

Insulin-stimulated leptin secretion requires calcium and PI3K/Akt activation

(2014) Yue Wang et al.   BIOCHEMICAL JOURNAL

Potential for primary prevention of Alzheimer's disease: an analysis of population-based data

(2014) Sam Norton et al.   LANCET NEUROLOGY

Modeling type 2 diabetes in rats using high fat diet and streptozotocin

(2014) Søs Skovsø   Journal of Diabetes Investigation

Deregulation of brain insulin signaling in Alzheimer’s disease

(2014) Yanxing Chen et al.   Neuroscience Bulletin

Brain Insulin Resistance and Deficiency as Therapeutic Targets in Alzheimers Disease

(2012) Suzanne M. de la Monte   Current Alzheimer Research

Transient Receptor Potential Vanilloid 1 Activation Enhances Gut Glucagon-Like Peptide-1 Secretion and Improves Glucose Homeostasis

(2012) P. Wang et al.   DIABETES

Combined medium-chain triglyceride and chilli feeding increases diet-induced thermogenesis in normal-weight humans

(2012) Miriam E. Clegg et al.   EUROPEAN JOURNAL OF NUTRITION

The development of effective biomarkers for Alzheimer's disease: a review

(2012) Mark S. Henry et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

GSK3: a key target for the development of novel treatments for type 2 diabetes mellitus and Alzheimer disease

(2012) Chong Gao et al.   REVIEWS IN THE NEUROSCIENCES

Current and Emerging Drug Treatment Options for Alzheimerʼs Disease

(2011) Nathan Herrmann et al.   DRUGS

Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes

(2011) Ying Liu et al.   JOURNAL OF PATHOLOGY

Caloric restriction

(2011) John R. Speakman et al.   MOLECULAR ASPECTS OF MEDICINE

Targeting Tau Protein in Alzheimerʼs Disease

(2010) Cheng-Xin Gong et al.   DRUGS & AGING

Phosphatidylinositol 3-Kinase (PI3K) Signaling via Glycogen Synthase Kinase-3 (Gsk-3) Regulates DNA Methylation of Imprinted Loci

(2010) Anthony P. Popkie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dietary Capsaicin Reduces Obesity-induced Insulin Resistance and Hepatic Steatosis in Obese Mice Fed a High-fat Diet

(2009) Ji-Hye Kang et al.   Obesity

Hot flash: TRPV channels in the brain

(2009) Julie A. Kauer et al.   TRENDS IN NEUROSCIENCES

Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling

(2008) Aileen M. Moloney et al.   NEUROBIOLOGY OF AGING