TGFbeta Induces Binucleation/Polyploidization in Hepatocytes through a Src-Dependent Cytokinesis Failure

Molecular mechanisms controlling the phenotype and the EMT/MET dynamics of hepatocyte

(2014) Carla Cicchini et al.   LIVER INTERNATIONAL

v-Src causes delocalization of Mklp1, Aurora B, and INCENP from the spindle midzone during cytokinesis failure

(2013) Shuhei Soeda et al.   EXPERIMENTAL CELL RESEARCH

p53 regulates a mitotic transcription program and determines ploidy in normal mouse liver

(2013) Svitlana Kurinna et al.   HEPATOLOGY

Aneuploidy, polyploidy and ploidy reversal in the liver

(2013) Andrew W. Duncan   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Physiological significance of polyploidization in mammalian cells

(2013) Shusil K. Pandit et al.   TRENDS IN CELL BIOLOGY

LY2109761 Attenuates Radiation-Induced Pulmonary Murine Fibrosis via Reversal of TGF-  and BMP-Associated Proinflammatory and Proangiogenic Signals

(2012) P. Flechsig et al.   CLINICAL CANCER RESEARCH

Editorial: [Hot Topic: TGF-β1 in Pre-Malignant and Malignant Liver Disease]

(2012) Gianluigi Giannelli   CURRENT PHARMACEUTICAL DESIGN

Centralspindlin: At the heart of cytokinesis

(2012) Erin A. White et al.   Cytoskeleton

Aneuploidy as a mechanism for stress-induced liver adaptation

(2012) Andrew W. Duncan et al.   JOURNAL OF CLINICAL INVESTIGATION

Midbody assembly and its regulation during cytokinesis

(2012) Chi-Kuo Hu et al.   MOLECULAR BIOLOGY OF THE CELL

Involvement of Endoplasmic Reticulum Stress in Myofibroblastic Differentiation of Lung Fibroblasts

(2011) Hyun Ah Baek et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The Causes and Consequences of Polyploidy in Normal Development and Cancer

(2011) Teresa Davoli et al.   Annual Review of Cell and Developmental Biology

Blockade of TGF-  Signaling by the TGF R-I Kinase Inhibitor LY2109761 Enhances Radiation Response and Prolongs Survival in Glioblastoma

(2011) M. Zhang et al.   CANCER RESEARCH

The stable repression of mesenchymal program is required for hepatocyte identity: A novel role for hepatocyte nuclear factor 4α

(2011) Laura Santangelo et al.   HEPATOLOGY

The new murine hepatic 3A cell line responds to stress stimuli by activating an efficient Unfolded Protein Response (UPR)

(2011) Barbara Guantario et al.   TOXICOLOGY IN VITRO

Polyploidy and liver proliferation: Central role of insulin signaling

(2010) Séverine Celton-Morizur et al.   CELL CYCLE

The ploidy conveyor of mature hepatocytes as a source of genetic variation

(2010) Andrew W. Duncan et al.   NATURE

Mechanisms of Liver Development: Concepts for Understanding Liver Disorders and Design of Novel Therapies

(2009) Frédéric P. Lemaigre   GASTROENTEROLOGY

Transforming Growth Factor-β/Smad3 Signaling Regulates Insulin Gene Transcription and Pancreatic Islet β-Cell Function

(2009) Huei-Min Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ERK5/MAPK is activated by TGFβ in hepatocytes and required for the GSK-3β-mediated Snail protein stabilization

(2008) Alessandra Marchetti et al.   CELLULAR SIGNALLING

Epithelial-to-mesenchymal transition of peritoneal mesothelial cells is regulated by an ERK/NF- B/Snail1 pathway

(2008) R. Strippoli et al.   Disease Models & Mechanisms

LY2109761, a novel transforming growth factor   receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis

(2008) D. Melisi et al.   MOLECULAR CANCER THERAPEUTICS

TGFβ-induced EMT requires focal adhesion kinase (FAK) signaling

(2007) Carla Cicchini et al.   EXPERIMENTAL CELL RESEARCH