HMGA2 Moderately Increases Fetal Hemoglobin Expression in Human Adult Erythroblasts

Beyond hydroxyurea: new and old drugs in the pipeline for sickle cell disease

(2016) M. J. Telen   BLOOD

Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin

(2016) T. Masuda et al.   SCIENCE

BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis

(2015) Matthew C. Canver et al.   NATURE

Erythroid-Specific Expression of LIN28A Is Sufficient for Robust Gamma-Globin Gene and Protein Expression in Adult Erythroblasts

(2015) Y. Terry Lee et al.   PLoS One

Epidemiology: A moving target

(2014) Simon Pleasants   NATURE

LIN28A Expression Reduces Sickling of Cultured Human Erythrocytes

(2014) Jaira F. de Vasconcellos et al.   PLoS One

LIN28B-mediated expression of fetal hemoglobin and production of fetal-like erythrocytes from adult human erythroblasts ex vivo

(2013) Y. T. Lee et al.   BLOOD

The Lin28b–let-7–Hmga2 axis determines the higher self-renewal potential of fetal haematopoietic stem cells

(2013) Michael R. Copley et al.   NATURE CELL BIOLOGY

A Synthetic Model of Human Beta-Thalassemia Erythropoiesis Using CD34+ Cells from Healthy Adult Donors

(2013) Y. Terry Lee et al.   PLoS One

An Erythroid Enhancer of BCL11A Subject to Genetic Variation Determines Fetal Hemoglobin Level

(2013) D. E. Bauer et al.   SCIENCE

3'UTR-truncated Hmga2 cDNA causes MPN-like hematopoiesis by conferring a clonal growth advantage at the level of HSC in mice

(2011) K. Ikeda et al.   BLOOD

Lin28A and Lin28B Inhibit let-7 MicroRNA Biogenesis by Distinct Mechanisms

(2011) Elena Piskounova et al.   CELL

Correction of Sickle Cell Disease in Adult Mice by Interference with Fetal Hemoglobin Silencing

(2011) J. Xu et al.   SCIENCE

Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia

(2010) Marina Cavazzana-Calvo et al.   NATURE

Cytokine-mediated increases in fetal hemoglobin are associated with globin gene histone modification and transcription factor reprogramming

(2009) O. Sripichai et al.   BLOOD

Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells

(2009) T. Tanno et al.   BLOOD

Let-7 microRNAs are developmentally regulated in circulating human erythroid cells

(2009) Seung-Jae Noh et al.   Journal of Translational Medicine

Identification of Let-7-Regulated Oncofetal Genes

(2008) B. Boyerinas et al.   CANCER RESEARCH

Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of  -thalassemia

(2008) M. Uda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA