LIN28A Expression Reduces Sickling of Cultured Human Erythrocytes

Direct measurement of local oxygen concentration in the bone marrow of live animals

(2014) Joel A. Spencer et al.   NATURE

The Role of the Inherited Disorders of Hemoglobin, the First “Molecular Diseases,” in the Future of Human Genetics

(2013) David J. Weatherall   Annual Review of Genomics and Human Genetics

LIN28B-mediated expression of fetal hemoglobin and production of fetal-like erythrocytes from adult human erythroblasts ex vivo

(2013) Y. T. Lee et al.   BLOOD

Candidate Sequence Variants and Fetal Hemoglobin in Children with Sickle Cell Disease Treated with Hydroxyurea

(2013) Nancy S. Green et al.   PLoS One

The Switch from Fetal to Adult Hemoglobin

(2013) V. G. Sankaran et al.   Cold Spring Harbor Perspectives in Medicine

Hydroxycarbamide alters erythroid gene expression in children with sickle cell anaemia

(2012) Jonathan M. Flanagan et al.   BRITISH JOURNAL OF HAEMATOLOGY

Correction of Sickle Cell Disease in Adult Mice by Interference with Fetal Hemoglobin Silencing

(2011) J. Xu et al.   SCIENCE

Sickle Cell Biomechanics

(2010) Gilda A. Barabino et al.   Annual Review of Biomedical Engineering

Low physiologic oxygen tensions reduce proliferation and differentiation of human multipotent mesenchymal stromal cells

(2010) Christina Holzwarth et al.   BMC CELL BIOLOGY

Lin28: A MicroRNA Regulator with a Macro Role

(2010) Srinivas R. Viswanathan et al.   CELL

Transcriptional silencing of  -globin by BCL11A involves long-range interactions and cooperation with SOX6

(2010) J. Xu et al.   GENES & DEVELOPMENT

KLF1 regulates BCL11A expression and γ- to β-globin gene switching

(2010) Dewang Zhou et al.   NATURE GENETICS

Expression patterns of fetal hemoglobin in sickle cell erythrocytes are both patient- and treatment-specific during childhood

(2010) Emily Riehm Meier et al.   PEDIATRIC BLOOD & CANCER

Cytokine-mediated increases in fetal hemoglobin are associated with globin gene histone modification and transcription factor reprogramming

(2009) O. Sripichai et al.   BLOOD

Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells

(2009) T. Tanno et al.   BLOOD

Let-7 microRNAs are developmentally regulated in circulating human erythroid cells

(2009) Seung-Jae Noh et al.   Journal of Translational Medicine

Genome-wide association studies identify loci associated with age at menarche and age at natural menopause

(2009) Chunyan He et al.   NATURE GENETICS

Genetic variation in LIN28B is associated with the timing of puberty

(2009) Ken K Ong et al.   NATURE GENETICS

Hemoglobin research and the origins of molecular medicine

(2008) A. N. Schechter   BLOOD

BCL11A is a major HbF quantitative trait locus in three different populations with β-hemoglobinopathies

(2008) Amanda E. Sedgewick et al.   BLOOD CELLS MOLECULES AND DISEASES

Identification of ten loci associated with height highlights new biological pathways in human growth

(2008) Guillaume Lettre et al.   NATURE GENETICS

Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of  -thalassemia

(2008) M. Uda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Fetal Hemoglobin Expression Is Regulated by the Developmental Stage-Specific RepressorBCL11A

(2008) Vijay G. Sankaran et al.   SCIENCE