MAP3K19 Is Overexpressed in COPD and Is a Central Mediator of Cigarette Smoke-Induced Pulmonary Inflammation and Lower Airway Destruction

B cells in chronic obstructive pulmonary disease: moving to center stage

(2016) Francesca Polverino et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

COPD and stroke: are systemic inflammation and oxidative stress the missing links?

(2016) V. Austin et al.   CLINICAL SCIENCE

MAP3K19 Is a Novel Regulator of TGF-β Signaling That Impacts Bleomycin-Induced Lung Injury and Pulmonary Fibrosis

(2016) Stefen A. Boehme et al.   PLoS One

Cigarette Smoke–Induced Damage-Associated Molecular Pattern Release from Necrotic Neutrophils Triggers Proinflammatory Mediator Release

(2015) Irene H. Heijink et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Pulmonary Epithelial Cell-Derived Cytokine TGF-β1 Is a Critical Cofactor for Enhanced Innate Lymphoid Cell Function

(2015) Laura Denney et al.   IMMUNITY

Targeting oxidant-dependent mechanisms for the treatment of COPD and its comorbidities

(2015) Ivan Bernardo et al.   PHARMACOLOGY & THERAPEUTICS

Bronchial epithelial cells: The key effector cells in the pathogenesis of chronic obstructive pulmonary disease?

(2015) Wei Gao et al.   RESPIROLOGY

Correlation of Cigarette Smoke-Induced Pulmonary Inflammation and Emphysema in C3H and C57Bl/6 Mice

(2015) Elias G. Awji et al.   TOXICOLOGICAL SCIENCES

Chronic obstructive pulmonary disease

(2015) Peter J. Barnes et al.   Nature Reviews Disease Primers

Cigarette Smoke Extract Induces a Phenotypic Shift in Epithelial Cells; Involvement of HIF1α in Mesenchymal Transition

(2014) Irene M. J. Eurlings et al.   PLoS One

Oxidative Stress in COPD

(2013) Paul A. Kirkham et al.   CHEST

Cellular and Molecular Mechanisms of Chronic Obstructive Pulmonary Disease

(2013) Peter J. Barnes   CLINICS IN CHEST MEDICINE

SALT-RESPONSIVE ERF1 Regulates Reactive Oxygen Species-Dependent Signaling during the Initial Response to Salt Stress in Rice

(2013) R. Schmidt et al.   PLANT CELL

Recent advances in understanding inflammation and remodeling in the airways in chronic obstructive pulmonary disease

(2013) Sukhwinder Singh Sohal et al.   Expert Review of Respiratory Medicine

Inflammation in COPD: Implications for Management

(2012) Sanjay Sethi et al.   AMERICAN JOURNAL OF MEDICINE

Oxidative Stress and Chromatin Remodeling in Chronic Obstructive Pulmonary Disease and Smoking-Related Diseases

(2012) Isaac K. Sundar et al.   ANTIOXIDANTS & REDOX SIGNALING

COPD Exacerbations

(2012) Alex J. Mackay et al.   IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Rafael Lozano et al.   LANCET

The Airway Epithelium: Soldier in the Fight against Respiratory Viruses

(2011) M. Vareille et al.   CLINICAL MICROBIOLOGY REVIEWS

Angiotensin receptor blockade attenuates cigarette smoke–induced lung injury and rescues lung architecture in mice

(2011) Megan Podowski et al.   JOURNAL OF CLINICAL INVESTIGATION

Small-Airway Obstruction and Emphysema in Chronic Obstructive Pulmonary Disease

(2011) John E. McDonough et al.   NEW ENGLAND JOURNAL OF MEDICINE

Smoking and emphysema: the stress connection

(2010) Leif W Ellisen   NATURE MEDICINE

RNAi-mediated suppression of constitutive pulmonary gene expression by small interfering RNA in mice

(2010) Birgitt Gutbier et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Neutrophils Find Smoke Attractive

(2010) P. J. Barnes   SCIENCE

Management and prevention of chronic obstructive pulmonary disease exacerbations: a state of the art review

(2009) John R Hurst et al.   BMC Medicine

Lymphoid follicles in (very) severe COPD: beneficial or harmful?

(2009) G. G. Brusselle et al.   EUROPEAN RESPIRATORY JOURNAL

Assessment of air space size characteristics by intercept (chord) measurement: an accurate and efficient stereological approach

(2009) Lars Knudsen et al.   JOURNAL OF APPLIED PHYSIOLOGY

Small Interfering RNA against Transcription Factor STAT6 Inhibits Allergic Airway Inflammation and Hyperreactivity in Mice

(2009) Y. Darcan-Nicolaisen et al.   JOURNAL OF IMMUNOLOGY

Pharmacological Blockade of the DP2 Receptor Inhibits Cigarette Smoke-Induced Inflammation, Mucus Cell Metaplasia, and Epithelial Hyperplasia in the Mouse Lung

(2009) K. J. Stebbins et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Immunologic Aspects of Chronic Obstructive Pulmonary Disease

(2009) Manuel G. Cosio et al.   NEW ENGLAND JOURNAL OF MEDICINE

Smoking cessation in chronic obstructive pulmonary disease

(2009) Donald P. Tashkin et al.   RESPIRATORY MEDICINE

Cigarette Smoking and Diffuse Lung Disease

(2008) Rajesh R Patel et al.   DRUGS