Safety, Immunogenicity and Efficacy of Prime-Boost Vaccination with ChAd63 and MVA Encoding ME-TRAP against Plasmodium falciparum Infection in Adults in Senegal
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Title
Safety, Immunogenicity and Efficacy of Prime-Boost Vaccination with ChAd63 and MVA Encoding ME-TRAP against Plasmodium falciparum Infection in Adults in Senegal
Authors
Keywords
Vaccines, Malaria, Vaccination and immunization, Antigens, Enzyme-linked immunoassays, Parasitic diseases, Immune response, Senegal
Journal
PLoS One
Volume 11, Issue 12, Pages e0167951
Publisher
Public Library of Science (PLoS)
Online
2016-12-17
DOI
10.1371/journal.pone.0167951
References
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Related references
Note: Only part of the references are listed.- Safety and High Level Efficacy of the Combination Malaria Vaccine Regimen of RTS,S/AS01BWith Chimpanzee Adenovirus 63 and Modified Vaccinia Ankara Vectored Vaccines Expressing ME-TRAP
- (2016) Tommy Rampling et al. JOURNAL OF INFECTIOUS DISEASES
- Prime-boost vaccination with chimpanzee adenovirus and modified vaccinia Ankara encoding TRAP provides partial protection against Plasmodium falciparum infection in Kenyan adults
- (2015) Caroline Ogwang et al. Science Translational Medicine
- Comparative assessment of vaccine vectors encoding ten malaria antigens identifies two protective liver-stage candidates
- (2015) Rhea J. Longley et al. Scientific Reports
- Assessment of Chimpanzee Adenovirus Serotype 63 Neutralizing Antibodies Prior to Evaluation of a Candidate Malaria Vaccine Regimen Based on Viral Vectors
- (2014) Issa Nébié et al. Clinical and Vaccine Immunology
- Evaluation of the Efficacy of ChAd63-MVA Vectored Vaccines Expressing Circumsporozoite Protein and ME-TRAP Against Controlled Human Malaria Infection in Malaria-Naive Individuals
- (2014) Susanne H. Hodgson et al. JOURNAL OF INFECTIOUS DISEASES
- Translating the Immunogenicity of Prime-boost Immunization With ChAd63 and MVA ME-TRAP From Malaria Naive to Malaria-endemic Populations
- (2014) Domtila Kimani et al. MOLECULAR THERAPY
- Safety and Immunogenicity of Heterologous Prime-Boost Immunisation with Plasmodium falciparum Malaria Candidate Vaccines, ChAd63 ME-TRAP and MVA ME-TRAP, in Healthy Gambian and Kenyan Adults
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- DNA Prime/Adenovirus Boost Malaria Vaccine Encoding P. falciparum CSP and AMA1 Induces Sterile Protection Associated with Cell-Mediated Immunity
- (2013) Ilin Chuang et al. PLoS One
- Clinical Assessment of a Recombinant Simian Adenovirus ChAd63: A Potent New Vaccine Vector
- (2012) Geraldine A. O’Hara et al. JOURNAL OF INFECTIOUS DISEASES
- ChAd63-MVA–vectored Blood-stage Malaria Vaccines Targeting MSP1 and AMA1: Assessment of Efficacy Against Mosquito Bite Challenge in Humans
- (2012) Susanne H Sheehy et al. MOLECULAR THERAPY
- Efficacy of RTS,S/AS01E malaria vaccine and exploratory analysis on anti-circumsporozoite antibody titres and protection in children aged 5–17 months in Kenya and Tanzania: a randomised controlled trial
- (2011) Ally Olotu et al. LANCET INFECTIOUS DISEASES
- Phase Ia Clinical Evaluation of the Plasmodium falciparum Blood-stage Antigen MSP1 in ChAd63 and MVA Vaccine Vectors
- (2011) Susanne H Sheehy et al. MOLECULAR THERAPY
- First Results of Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Children
- (2011) NEW ENGLAND JOURNAL OF MEDICINE
- Malaria elimination: worthy, challenging, and just possible
- (2010) Pam Das et al. LANCET
- Eliminating malaria—all of them
- (2010) J Kevin Baird LANCET
- Continued Decline of Malaria in The Gambia with Implications for Elimination
- (2010) Serign J. Ceesay et al. PLoS One
- Safety of the Malaria Vaccine Candidate, RTS,S/AS01E in 5 to 17 Month Old Kenyan and Tanzanian Children
- (2010) John Lusingu et al. PLoS One
- Highly focused anopheline breeding sites and malaria transmission in Dakar
- (2009) Vanessa Machault et al. MALARIA JOURNAL
- Efficacy of RTS,S/AS01E Vaccine against Malaria in Children 5 to 17 Months of Age
- (2008) Philip Bejon et al. NEW ENGLAND JOURNAL OF MEDICINE
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