Agmatine Reduces Lipopolysaccharide-Mediated Oxidant Response via Activating PI3K/Akt Pathway and Up-Regulating Nrf2 and HO-1 Expression in Macrophages

Co-spray dried resveratrol and budesonide inhalation formulation for reducing inflammation and oxidative stress in rat alveolar macrophages

(2016) Valentina Trotta et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Diverse Nrf2 Activators Coordinated to Cobalt Carbonyls Induce Heme Oxygenase-1 and Release Carbon Monoxide in Vitro and in Vivo

(2016) Aniket Nikam et al.   JOURNAL OF MEDICINAL CHEMISTRY

Role for the PI3K/Akt/Nrf2 signaling pathway in the protective effects of carnosic acid against methylglyoxal-induced neurotoxicity in SH-SY5Y neuroblastoma cells

(2015) Marcos Roberto de Oliveira et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Sonchus asperextract inhibits LPS-induced oxidative stress and pro-inflammatory cytokine production in RAW264.7 macrophages

(2015) Lan Wang et al.   Nutrition Research and Practice

Electroacupuncture Ameliorates Acute Renal Injury in Lipopolysaccharide-Stimulated Rabbits via Induction of HO-1 through the PI3K/Akt/Nrf2 Pathways

(2015) Jian-bo Yu et al.   PLoS One

PI3K-AKT Signaling via Nrf2 Protects against Hyperoxia-Induced Acute Lung Injury, but Promotes Inflammation Post-Injury Independent of Nrf2 in Mice

(2015) Narsa M. Reddy et al.   PLoS One

Depressive-like behavior induced by tumor necrosis factor-α is abolished by agmatine administration

(2014) Vivian Binder Neis et al.   BEHAVIOURAL BRAIN RESEARCH

Design and Synthesis of New Hybrid Molecules That Activate the Transcription Factor Nrf2 and Simultaneously Release Carbon Monoxide

(2014) Jayne Louise Wilson et al.   CHEMISTRY-A EUROPEAN JOURNAL

Imidazoline binding sites mediates anticompulsive-like effect of agmatine in marble-burying behavior in mice

(2014) Madhura P. Dixit et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Agmatine Induces Nrf2 and Protects Against Corticosterone Effects in Hippocampal Neuronal Cell Line

(2014) Andiara E. Freitas et al.   MOLECULAR NEUROBIOLOGY

Garlic Attenuates Cardiac Oxidative Stress via Activation of PI3K/AKT/Nrf2-Keap1 Pathway in Fructose-Fed Diabetic Rat

(2014) Raju Padiya et al.   PLoS One

Keap1-Nrf2 signaling pathway: Mechanisms of regulation and role in protection of cells against toxicity caused by xenobiotics and electrophiles

(2013) K. T. Turpaev   BIOCHEMISTRY-MOSCOW

Small molecule activators of the Nrf2-HO-1 antioxidant axis modulate heme metabolism and inflammation in BV2 microglia cells

(2013) Roberta Foresti et al.   PHARMACOLOGICAL RESEARCH

Agmatine abolishes restraint stress-induced depressive-like behavior and hippocampal antioxidant imbalance in mice

(2013) Andiara E. Freitas et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Free radical-operated proteotoxic stress in macrophages primed with lipopolysaccharide

(2012) Zili Zhai et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Keap1–Nrf2 system as an in vivo sensor for electrophiles

(2011) Akira Uruno et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Effects of agmatine on hypoxic microglia and activity of nitric oxide synthase

(2010) Soo Kyung Ahn et al.   BRAIN RESEARCH

Role of Nrf2 in Suppressing LPS-Induced Inflammation in Mouse Peritoneal Macrophages by Polyunsaturated Fatty Acids Docosahexaenoic Acid and Eicosapentaenoic Acid

(2010) Hu Wang et al.   MOLECULAR PHARMACEUTICS

Neuroprotective effects of agmatine on oxygen-glucose deprived primary-cultured astrocytes and nuclear translocation of nuclear factor-kappa B

(2009) Won Taek Lee et al.   BRAIN RESEARCH

Structure−Activity Relationships of Methoxychalcones as Inducers of Heme Oxygenase-1

(2008) Philip Sawle et al.   CHEMICAL RESEARCH IN TOXICOLOGY