Design and Synthesis of New Hybrid Molecules That Activate the Transcription Factor Nrf2 and Simultaneously Release Carbon Monoxide

Dimethyl Fumarate: A Review of Its Use in Patients with Relapsing-Remitting Multiple Sclerosis

(2014) Celeste B. Burness et al.   CNS DRUGS

Isothiocyanate–cysteine conjugates protect renal tissue against cisplatin-induced apoptosis via induction of heme oxygenase-1

(2014) Yasin Tayem et al.   PHARMACOLOGICAL RESEARCH

CO-releasing molecules: avoiding toxicity and exploiting the beneficial effects of CO for the treatment of cardiovascular disorders

(2013) Roberta Foresti et al.   Future Medicinal Chemistry

Small molecule activators of the Nrf2-HO-1 antioxidant axis modulate heme metabolism and inflammation in BV2 microglia cells

(2013) Roberta Foresti et al.   PHARMACOLOGICAL RESEARCH

Antithrombotic Properties of Water-Soluble Carbon Monoxide-Releasing Molecules

(2012) Karol Kramkowski et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Fumarate Is Cardioprotective via Activation of the Nrf2 Antioxidant Pathway

(2012) Houman Ashrafian et al.   Cell Metabolism

A Reaction-Based Fluorescent Probe for Selective Imaging of Carbon Monoxide in Living Cells Using a Palladium-Mediated Carbonylation

(2012) Brian W. Michel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Vasorelaxing effects and inhibition of nitric oxide in macrophages by new iron-containing carbon monoxide-releasing molecules (CO-RMs)

(2012) Roberto Motterlini et al.   PHARMACOLOGICAL RESEARCH

Acyloxybutadiene Iron Tricarbonyl Complexes as Enzyme-Triggered CO-Releasing Molecules (ET-CORMs)

(2011) Steffen Romanski et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Differential Antibacterial Activity Against Pseudomonas aeruginosa by Carbon Monoxide-Releasing Molecules

(2011) Mathieu Desmard et al.   ANTIOXIDANTS & REDOX SIGNALING

Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway

(2011) Ralf A. Linker et al.   BRAIN

CORM-3, a carbon monoxide-releasing molecule, alters the inflammatory response and reduces brain damage in a rat model of hemorrhagic stroke*

(2011) Andriy Yabluchanskiy et al.   CRITICAL CARE MEDICINE

[Mn(CO)4{S2CNMe(CH2CO2H)}], a new water-soluble CO-releasing molecule

(2011) Sian H. Crook et al.   DALTON TRANSACTIONS

Modification of the deoxy-myoglobin/carbonmonoxy-myoglobin UV-vis assay for reliable determination of CO-release rates from organometallic carbonyl complexes

(2011) Anthony J. Atkin et al.   DALTON TRANSACTIONS

17 e−rhenium dicarbonyl CO-releasing molecules on a cobalamin scaffold for biological application

(2011) Fabio Zobi et al.   DALTON TRANSACTIONS

Quantifying oxidation rates of carbon monoxide on a Pt/C electrode

(2011) S. Balasubramanian et al.   ELECTROCHIMICA ACTA

CORM-3 Reactivity toward Proteins: The Crystal Structure of a Ru(II) Dicarbonyl−Lysozyme Complex

(2011) Teresa Santos-Silva et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The therapeutic potential of carbon monoxide

(2010) Roberto Motterlini et al.   NATURE REVIEWS DRUG DISCOVERY

Fumaric acid dialkyl esters deprive cultured rat oligodendroglial cells of glutathione and upregulate the expression of heme oxygenase 1

(2010) Anette Thiessen et al.   NEUROSCIENCE LETTERS

μ2-Alkyne dicobalt(0)hexacarbonyl complexes as carbon monoxide-releasing molecules (CO-RMs): probing the release mechanism

(2009) Anthony J. Atkin et al.   DALTON TRANSACTIONS

Structure−Activity Relationships of Methoxychalcones as Inducers of Heme Oxygenase-1

(2008) Philip Sawle et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Alkyne hexacarbonyl dicobalt complexes in medicinal chemistry and drug development

(2008) Ingo Ott et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study

(2008) Ludwig Kappos et al.   LANCET

Synthesis of Well-Defined Figure-of-Eight-Shaped Polymers by a Combination of ATRP and Click Chemistry

(2008) Gang-Yin Shi et al.   MACROMOLECULAR RAPID COMMUNICATIONS