Heparanase: A Potential New Factor Involved in the Renal Epithelial Mesenchymal Transition (EMT) Induced by Ischemia/Reperfusion (I/R) Injury

Heparanase: a rainbow pharmacological target associated to multiple pathologies including rare diseases

(2016) Silvia Rivara et al.   Future Medicinal Chemistry

Kinetic analysis and molecular modeling of the inhibition mechanism of roneparstat (SST0001) on human heparanase

(2016) Daniele Pala et al.   GLYCOBIOLOGY

Sulodexide alone or in combination with low doses of everolimus inhibits the hypoxia-mediated epithelial to mesenchymal transition in human renal proximal tubular cells

(2015) Gianluigi Zaza et al.   JOURNAL OF NEPHROLOGY

Impact of heparanase on renal fibrosis

(2015) Valentina Masola et al.   Journal of Translational Medicine

Heparanase is a key player in renal fibrosis by regulating TGF-β expression and activity

(2014) Valentina Masola et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Heparanase Cooperates with Ras to Drive Breast and Skin Tumorigenesis

(2014) I. Boyango et al.   CANCER RESEARCH

The effect of ischemia/reperfusion on the kidney graft

(2014) Julia Menke et al.   Current Opinion in Organ Transplantation

Predictive model for delayed graft function based on easily available pre-renal transplant variables

(2014) Gianluigi Zaza et al.   Internal and Emergency Medicine

Cellular and molecular mechanisms in kidney fibrosis

(2014) Jeremy S. Duffield   JOURNAL OF CLINICAL INVESTIGATION

Origin and function of myofibroblasts in kidney fibrosis

(2013) Valerie S LeBleu et al.   NATURE MEDICINE

The role of heparanase and the endothelial glycocalyx in the development of proteinuria

(2013) Marjolein Garsen et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Ischaemia-reperfusion injury: a major protagonist in kidney transplantation

(2013) C. Ponticelli   NEPHROLOGY DIALYSIS TRANSPLANTATION

Hypoxia Inducible Factor 1-Alpha (HIF-1 Alpha) Is Induced during Reperfusion after Renal Ischemia and Is Critical for Proximal Tubule Cell Survival

(2012) Elisa Conde et al.   PLoS One

Regulation of heparanase by albumin and advanced glycation end products in proximal tubular cells

(2011) Valentina Masola et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The role of EMT in renal fibrosis

(2011) Rosemarie M. Carew et al.   CELL AND TISSUE RESEARCH

Heparanase Is Essential for the Development of Diabetic Nephropathy in Mice

(2011) N. Gil et al.   DIABETES

Heparanase and Syndecan-1 Interplay Orchestrates Fibroblast Growth Factor-2-induced Epithelial-Mesenchymal Transition in Renal Tubular Cells

(2011) Valentina Masola et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heparanase-mediated Loss of Nuclear Syndecan-1 Enhances Histone Acetyltransferase (HAT) Activity to Promote Expression of Genes That Drive an Aggressive Tumor Phenotype

(2011) Anurag Purushothaman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ischemia and reperfusion—from mechanism to translation

(2011) Holger K Eltzschig et al.   NATURE MEDICINE

Hypoxia and Inflammation

(2011) Holger K. Eltzschig et al.   NEW ENGLAND JOURNAL OF MEDICINE

Macrophages, Dendritic Cells, and Kidney Ischemia-Reperfusion Injury

(2010) Li Li et al.   SEMINARS IN NEPHROLOGY

Cell Death

(2009) Richard S. Hotchkiss et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hypoxia and Hypoxia-Inducible Factor in Renal Disease

(2008) Masaomi Nangaku et al.   NEPHRON EXPERIMENTAL NEPHROLOGY

Ischemia/Reperfusion Injury in Kidney Transplantation: Mechanisms and Prevention

(2008) M. Kosieradzki et al.   TRANSPLANTATION PROCEEDINGS