Cystatin C Shifts APP Processing from Amyloid-β Production towards Non-Amyloidgenic Pathway in Brain Endothelial Cells

Reduced Levels of Amyloid-β-Binding Proteins in Cerebrospinal Fluid from Alzheimer's Disease Patients

(2017) Sara F. Hansson et al.   JOURNAL OF ALZHEIMERS DISEASE

Cystatin C Protects Neuronal Cells from Amyloid-β-induced Toxicity

(2017) Belen Tizon et al.   JOURNAL OF ALZHEIMERS DISEASE

Amyloid properties of the leader peptide of variant B cystatin C: implications for Alzheimer and macular degeneration

(2016) Ricardo Sant'Anna et al.   FEBS LETTERS

CHIP stabilizes amyloid precursor protein via proteasomal degradation and p53-mediated trans-repression of β-secretase

(2015) Amir Kumar Singh et al.   AGING CELL

A missense variant in CST3 exerts a recessive effect on susceptibility to age-related macular degeneration resembling its association with Alzheimer’s disease

(2015) Joe M. Butler et al.   HUMAN GENETICS

Clearance systems in the brain—implications for Alzheimer disease

(2015) Jenna M. Tarasoff-Conway et al.   Nature Reviews Neurology

Cystatin C Has a Dual Role in Post-Traumatic Brain Injury Recovery

(2014) Marina Martinez-Vargas et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cilostazol suppresses β-amyloid production by activating a disintegrin and metalloproteinase 10 via the upregulation of SIRT1-coupled retinoic acid receptor-β

(2014) Hye Rin Lee et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Targeting the β secretase BACE1 for Alzheimer's disease therapy

(2014) Riqiang Yan et al.   LANCET NEUROLOGY

Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models

(2013) Bing Gong et al.   NEUROBIOLOGY OF AGING

Transcriptional and post-transcriptional regulation of β-secretase

(2012) Elena Tamagno et al.   IUBMB LIFE

Docosahexaenoic Acid-Derived Neuroprotectin D1 Induces Neuronal Survival via Secretase- and PPARγ-Mediated Mechanisms in Alzheimer's Disease Models

(2011) Yuhai Zhao et al.   PLoS One

APP processing in Alzheimer's disease

(2011) Yun-wu Zhang et al.   Molecular Brain

Endothelial Nitric Oxide Modulates Expression and Processing of Amyloid Precursor Protein

(2010) Susan A. Austin et al.   CIRCULATION RESEARCH

ADAM10 is the physiologically relevant, constitutive α-secretase of the amyloid precursor protein in primary neurons

(2010) Peer-Hendrik Kuhn et al.   EMBO JOURNAL

Brain Endothelial Cells Produce Amyloid β from Amyloid Precursor Protein 770 and Preferentially Secrete theO-Glycosylated Form

(2010) Shinobu Kitazume et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Disintegrin/Metalloproteinase ADAM10 Is Essential for the Establishment of the Brain Cortex

(2010) E. Jorissen et al.   JOURNAL OF NEUROSCIENCE

Capillary CAA and perivascular Aβ-deposition: Two distinct features of Alzheimer's disease pathology

(2010) Johannes Attems et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

l-3-n-Butylphthalide regulates amyloid precursor protein processing by PKC and MAPK pathways in SK-N-SH cells over-expressing wild type human APP695

(2010) Ying Peng et al.   NEUROSCIENCE LETTERS

Cooperation between myogenic regulatory factors and SIX family transcription factors is important for myoblast differentiation

(2010) Yubing Liu et al.   NUCLEIC ACIDS RESEARCH

Cystatins: Biochemical and structural properties, and medical relevance

(2008) ">Vito Turk   Frontiers in Bioscience-Landmark

Hydrogen Peroxide Promotes Aβ Production through JNK-dependent Activation of γ-Secretase

(2008) Chengyong Shen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid Precursor Protein Trafficking, Processing, and Function

(2008) Gopal Thinakaran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cystatin C-Cathepsin B Axis Regulates Amyloid Beta Levels and Associated Neuronal Deficits in an Animal Model of Alzheimer's Disease

(2008) Binggui Sun et al.   NEURON