Amyloid properties of the leader peptide of variant B cystatin C: implications for Alzheimer and macular degeneration

A missense variant in CST3 exerts a recessive effect on susceptibility to age-related macular degeneration resembling its association with Alzheimer’s disease

(2015) Joe M. Butler et al.   HUMAN GENETICS

Exploring the ‘aggregation-prone’ core of human Cystatin C: A structural study

(2015) Paraskevi L. Tsiolaki et al.   JOURNAL OF STRUCTURAL BIOLOGY

The pentapeptide LQVVR plays a pivotal role in human cystatin C fibrillization

(2014) Paraskevi L. Tsiolaki et al.   FEBS LETTERS

The Importance of a Gatekeeper Residue on the Aggregation of Transthyretin

(2014) Ricardo Sant'Anna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration

(2013) Kai Kaarniranta et al.   Autophagy

A Consensus Method for the Prediction of ‘Aggregation-Prone’ Peptides in Globular Proteins

(2013) Antonios C. Tsolis et al.   PLoS One

Natural polyphenols as modulators of TTR amyloidogenesis:in vitroandin vivoevidences towards therapy

(2012) Nelson Ferreira et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Meta-Analysis of the Cystatin C(CST3) Gene G73A Polymorphism and Susceptibility to Alzheimer's Disease

(2012) Ye Hua et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Prediction of amyloid aggregation in vivo

(2011) Mattia Belli et al.   EMBO REPORTS

Natural polyphenols inhibit different steps of the process of transthyretin (TTR) amyloid fibril formation

(2011) Nelson Ferreira et al.   FEBS LETTERS

Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration

(2011) J.-D. Ding et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of human cystatin C stabilized against amyloid formation

(2010) Robert Kolodziejczyk et al.   FEBS Journal

Human cystatin C, a cysteine proteinase inhibitor, inhibits bone resorption in vitro stimulated by parathyroid hormone and parathyroid hormone-related peptide of malignancy

(2010) Ulf H. Lerner et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Waltz, an exciting new move in amyloid prediction

(2010) Mikael Oliveberg   NATURE METHODS

Protein sequences encode safeguards against aggregation

(2009) Joke Reumers et al.   HUMAN MUTATION

The dynamic nature of Bruch's membrane

(2009) J.C. Booij et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Cystatin C in macular and neuronal degenerations: Implications for mechanism(s) of age-related macular degeneration

(2009) Luminita Paraoan et al.   VISION RESEARCH

A Drastic Reduction in the Life Span of Cystatin C L68Q Carriers Due to Life-Style Changes during the Last Two Centuries

(2008) Astridur Palsdottir et al.   PLoS Genetics