USP7 and TDP-43: Pleiotropic Regulation of Cryptochrome Protein Stability Paces the Oscillation of the Mammalian Circadian Clock

Structures of CYLD USP with Met1- or Lys63-linked diubiquitin reveal mechanisms for dual specificity

(2015) Yusuke Sato et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structures of CYLD USP with Met1- or Lys63-linked diubiquitin reveal mechanisms for dual specificity

(2015) Yusuke Sato et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The role of TDP-43 in the pathogenesis of ALS and FTLD: Figure 1

(2015) Marco Baralle et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

CUL4-DDB1-CDT2 E3 Ligase Regulates the Molecular Clock Activity by Promoting Ubiquitination-Dependent Degradation of the Mammalian CRY1

(2015) Xin Tong et al.   PLoS One

In Vivo Role of Phosphorylation of Cryptochrome 2 in the Mouse Circadian Clock

(2014) A. Hirano et al.   MOLECULAR AND CELLULAR BIOLOGY

USP17- and SCF TrCP-Regulated Degradation of DEC1 Controls the DNA Damage Response

(2014) J. Kim et al.   MOLECULAR AND CELLULAR BIOLOGY

Spatiotemporal separation of PER and CRY posttranslational regulation in the mammalian circadian clock

(2014) Peter C. St. John et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A central role for ubiquitination within a circadian clock protein modification code

(2014) Katarina Stojkovic et al.   Frontiers in Molecular Neuroscience

Competing E3 Ubiquitin Ligases Govern Circadian Periodicity by Degradation of CRY in Nucleus and Cytoplasm

(2013) Seung-Hee Yoo et al.   CELL

FBXL21 Regulates Oscillation of the Circadian Clock through Ubiquitination and Stabilization of Cryptochromes

(2013) Arisa Hirano et al.   CELL

Phosphorylation of the Cryptochrome 1 C-terminal Tail Regulates Circadian Period Length

(2013) Peng Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conserved RNA Helicase FRH Acts Nonenzymatically to Support the Intrinsically Disordered Neurospora Clock Protein FRQ

(2013) Jennifer M. Hurley et al.   MOLECULAR CELL

Dual roles of FBXL3 in the mammalian circadian feedback loops are important for period determination and robustness of the clock

(2013) G. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Ubiquitin Code

(2012) David Komander et al.   Annual Review of Biochemistry

USP2a Protein Deubiquitinates and Stabilizes the Circadian Protein CRY1 in Response to Inflammatory Signals

(2012) Xin Tong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RNA quality control and protein aggregates in amyotrophic lateral sclerosis: A review

(2012) Ashok Verma et al.   MUSCLE & NERVE

Identification of Small Molecule Activators of Cryptochrome

(2012) T. Hirota et al.   SCIENCE

Regulation of behavioral circadian rhythms and clock protein PER1 by the deubiquitinating enzyme USP2

(2012) Y. Yang et al.   Biology Open

The Multifaceted Roles of USP7: New Therapeutic Opportunities

(2011) Benjamin Nicholson et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

The De-Ubiquitinylating Enzyme, USP2, Is Associated with the Circadian Clockwork and Regulates Its Sensitivity to Light

(2011) Heather Dehlin Scoma et al.   PLoS One

RNA-binding proteins in neurodegenerative disease: TDP-43 and beyond

(2011) Keith A. Hanson et al.   Wiley Interdisciplinary Reviews-RNA

DYRK1A and Glycogen Synthase Kinase 3 , a Dual-Kinase Mechanism Directing Proteasomal Degradation of CRY2 for Circadian Timekeeping

(2010) N. Kurabayashi et al.   MOLECULAR AND CELLULAR BIOLOGY

Small-molecule inhibitor of USP7/HAUSP ubiquitin protease stabilizes and activates p53 in cells

(2009) F. Colland et al.   MOLECULAR CANCER THERAPEUTICS

AMPK Regulates the Circadian Clock by Cryptochrome Phosphorylation and Degradation

(2009) K. A. Lamia et al.   SCIENCE

Protein partners of deubiquitinating enzymes

(2008) Karen H. Ventii et al.   BIOCHEMICAL JOURNAL

ALS and FTLD: two faces of TDP-43 proteinopathy

(2008) R. M. Liscic et al.   EUROPEAN JOURNAL OF NEUROLOGY

Activation of TGF-β/activin signalling resets the circadian clock through rapid induction of Dec1 transcripts

(2008) Naohiro Kon et al.   NATURE CELL BIOLOGY