USP2a Protein Deubiquitinates and Stabilizes the Circadian Protein CRY1 in Response to Inflammatory Signals

De-ubiquitinating protease USP2a targets RIP1 and TRAF2 to mediate cell death by TNF

(2011) A-L Mahul-Mellier et al.   CELL DEATH AND DIFFERENTIATION

Impairment of Peripheral Circadian Clocks Precedes Metabolic Abnormalities in ob/ob Mice

(2011) Hitoshi Ando et al.   ENDOCRINOLOGY

An RNAi screen identifies USP2 as a factor required for TNF-α-induced NF-κB signaling

(2011) Marie Metzig et al.   INTERNATIONAL JOURNAL OF CANCER

Ubiquitin-specific Cysteine Protease 2a (USP2a) Regulates the Stability of Aurora-A

(2011) Yan Shi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Potorous CPD Photolyase Rescues a Cryptochrome-Deficient Mammalian Circadian Clock

(2011) Inês Chaves et al.   PLoS One

The De-Ubiquitinylating Enzyme, USP2, Is Associated with the Circadian Clockwork and Regulates Its Sensitivity to Light

(2011) Heather Dehlin Scoma et al.   PLoS One

The Role of Clock Genes in Pharmacology

(2010) Georgios K. Paschos et al.   Annual Review of Pharmacology and Toxicology

The Mammalian Circadian Timing System: Organization and Coordination of Central and Peripheral Clocks

(2010) Charna Dibner et al.   Annual Review of Physiology

A new map to understand deubiquitination: Table 1

(2010) Elijah J. Katz et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Poly(ADP-Ribose) Polymerase 1 Participates in the Phase Entrainment of Circadian Clocks to Feeding

(2010) Gad Asher et al.   CELL

The role of deubiquitinating enzymes in apoptosis

(2010) Suresh Ramakrishna et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Genomics and systems approaches in the mammalian circadian clock

(2010) Julie E Baggs et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/Wnt

(2010) Akiko Mukai et al.   EMBO JOURNAL

Dysregulation of Inflammatory Responses by Chronic Circadian Disruption

(2010) O. Castanon-Cervantes et al.   JOURNAL OF IMMUNOLOGY

DYRK1A and Glycogen Synthase Kinase 3 , a Dual-Kinase Mechanism Directing Proteasomal Degradation of CRY2 for Circadian Timekeeping

(2010) N. Kurabayashi et al.   MOLECULAR AND CELLULAR BIOLOGY

Loss of the Tumor Suppressor CYLD Enhances Wnt/β-Catenin Signaling through K63-Linked Ubiquitination of Dvl

(2010) Daniele V.F. Tauriello et al.   MOLECULAR CELL

Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis

(2010) Eric E Zhang et al.   NATURE MEDICINE

Expression of USP2-69 in mesangial cellsin vivoandin vitro

(2010) Suxia Wang et al.   PATHOLOGY INTERNATIONAL

Regulation of BMAL1 Protein Stability and Circadian Function by GSK3β-Mediated Phosphorylation

(2010) Saurabh Sahar et al.   PLoS One

E3 ligases Arf-bp1 and Pam mediate lithium-stimulated degradation of the circadian heme receptor Rev-erb 

(2010) L. Yin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reaction mechanism of Drosophila cryptochrome

(2010) N. Ozturk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circadian Integration of Metabolism and Energetics

(2010) J. Bass et al.   SCIENCE

Regulation and Cellular Roles of Ubiquitin-Specific Deubiquitinating Enzymes

(2009) Francisca E. Reyes-Turcu et al.   Annual Review of Biochemistry

Obesity alters circadian expressions of molecular clock genes in the brainstem

(2009) Keizo Kaneko et al.   BRAIN RESEARCH

Defining the Human Deubiquitinating Enzyme Interaction Landscape

(2009) Mathew E. Sowa et al.   CELL

A Genome-wide RNAi Screen for Modifiers of the Circadian Clock in Human Cells

(2009) Eric E. Zhang et al.   CELL

Clock Gene Modulation by TNF-α Depends on Calcium and p38 MAP Kinase Signaling

(2009) Saskia Petrzilka et al.   JOURNAL OF BIOLOGICAL RHYTHMS

The ubiquitin specific protease 4 (USP4) is a new player in the Wnt signalling pathway

(2009) Bin Zhao et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Mammalian Clock Gene Cryptochrome Regulates Arthritis via Proinflammatory Cytokine TNF- 

(2009) A. Hashiramoto et al.   JOURNAL OF IMMUNOLOGY

Suppression of Cancer Cell Growth by Promoting Cyclin D1 Degradation

(2009) Jing Shan et al.   MOLECULAR CELL

Salt-sensitive hypertension in circadian clock–deficient Cry-null mice involves dysregulated adrenal Hsd3b6

(2009) Masao Doi et al.   NATURE MEDICINE

MdmX is a substrate for the deubiquitinating enzyme USP2a

(2009) N Allende-Vega et al.   ONCOGENE

A circadian clock in macrophages controls inflammatory immune responses

(2009) Maren Keller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AMPK Regulates the Circadian Clock by Cryptochrome Phosphorylation and Degradation

(2009) K. A. Lamia et al.   SCIENCE

Network Features of the Mammalian Circadian Clock

(2009) Julie E Baggs et al.   PLOS BIOLOGY

Adiponectin differentially affects gene expression in human mammary epithelial and breast cancer cells

(2008) O Treeck et al.   BRITISH JOURNAL OF CANCER

The Meter of Metabolism

(2008) Carla B. Green et al.   CELL

SIRT1 Regulates Circadian Clock Gene Expression through PER2 Deacetylation

(2008) Gad Asher et al.   CELL

Down-regulation of the De-ubiquitinating Enzyme Ubiquitin-specific Protease 2 Contributes to Tumor Necrosis Factor-α-induced Hepatocyte Survival

(2008) Florian Haimerl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deubiquitylation Regulates Activation and Proteolytic Cleavage of ENaC

(2008) D. Ruffieux-Daidie et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The genetics of mammalian circadian order and disorder: implications for physiology and disease

(2008) Joseph S. Takahashi et al.   NATURE REVIEWS GENETICS

A High-Throughput Assay for siRNA-Based Circadian Screens in Human U2OS Cells

(2008) Christopher Vollmers et al.   PLoS One

Circadian rhythms in arthritis: Hormonal effects on the immune/inflammatory reaction

(2007) Maurizio Cutolo et al.   AUTOIMMUNITY REVIEWS