Cancer Stem Cells in Small Cell Lung Cancer Cell Line H446: Higher Dependency on Oxidative Phosphorylation and Mitochondrial Substrate-Level Phosphorylation than Non-Stem Cancer Cells

Inhibition of glucose turnover by 3-bromopyruvate counteracts pancreatic cancer stem cell features and sensitizes cells to gemcitabine

(2015) Orkhan Isayev et al.   Oncotarget

Targeting the facilitative glucose transporter GLUT1 inhibits the self-renewal and tumor-initiating capacity of cancer stem cells

(2015) Keita Shibuya et al.   Oncotarget

Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation

(2015) Anna Pastò et al.   Oncotarget

Metabolic reprogramming orchestrates cancer stem cell properties in nasopharyngeal carcinoma

(2014) Yao-An Shen et al.   CELL CYCLE

Mitochondrial diaphorases as NAD+ donors to segments of the citric acid cycle that support substrate-level phosphorylation yielding ATP during respiratory inhibition

(2014) Gergely Kiss et al.   FASEB JOURNAL

Integrated analysis identifies different metabolic signatures for tumor-initiating cells in a murine glioblastoma model

(2014) I. Saga et al.   NEURO-ONCOLOGY

Ovarian Cancer Spheroid Cells with Stem Cell-Like Properties Contribute to Tumor Generation, Metastasis and Chemotherapy Resistance through Hypoxia-Resistant Metabolism

(2014) Jianqun Liao et al.   PLoS One

Targeting Unique Metabolic Properties of Breast Tumor Initiating Cells

(2014) Weiguo Feng et al.   STEM CELLS

The cancer stem cell niche: cross talk between cancer stem cells and their microenvironment

(2014) Jun Ye et al.   TUMOR BIOLOGY

Breast cancer stem cells rely on fermentative glycolysis and are sensitive to 2-deoxyglucose treatment

(2014) D Ciavardelli et al.   Cell Death & Disease

BCL-2 Inhibition Targets Oxidative Phosphorylation and Selectively Eradicates Quiescent Human Leukemia Stem Cells

(2013) Eleni D. Lagadinou et al.   Cell Stem Cell

The negative impact of α-ketoglutarate dehydrogenase complex deficiency on matrix substrate-level phosphorylation

(2013) Gergely Kiss et al.   FASEB JOURNAL

2-Deoxyglucose treatment complements the cisplatin- or BH3-only mimetic-induced suppression of neuroblastoma cell growth

(2013) Jiin-Haur Chuang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Predictive Value of BRCA1, ERCC1, ATP7B, PKM2, TOPOI, TOPΟ-IIA, TOPOIIB and C-MYC Genes in Patients with Small Cell Lung Cancer (SCLC) Who Received First Line Therapy with Cisplatin and Etoposide

(2013) Niki Karachaliou et al.   PLoS One

Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3

(2013) P. Mao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer stem cells in lung cancer: Evidence and controversies

(2013) Muhammad Alamgeer et al.   RESPIROLOGY

The Many Spaces of uPAR: Delivery of Theranostic Agents and Nanobins to Multiple Tumor Compartments through a Single Target

(2013) Thomas V. O'Halloran et al.   Theranostics

Role of Urokinase Receptor in Tumor Progression and Development

(2013) Hyangsoon Noh et al.   Theranostics

Anti-mitochondrial therapy in human breast cancer multi-cellular spheroids

(2012) Edna Ayerim Mandujano-Tinoco et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Characterization of sphere-forming cells with stem-like properties from the small cell lung cancer cell line H446

(2012) Xiaofei Qiu et al.   CANCER LETTERS

Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cells

(2012) M. Janiszewska et al.   GENES & DEVELOPMENT

MicroRNA-143 (miR-143) Regulates Cancer Glycolysis via Targeting Hexokinase 2 Gene

(2012) Rong Fang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolic symbiosis in cancer: Refocusing the Warburg lens

(2012) Erica C. Nakajima et al.   MOLECULAR CARCINOGENESIS

Effective Elimination of Cancer Stem Cells By a Novel Drug Combination Strategy

(2012) Shuqiang Yuan et al.   STEM CELLS

SIRT3 Opposes Reprogramming of Cancer Cell Metabolism through HIF1α Destabilization

(2011) Lydia W.S. Finley et al.   CANCER CELL

Metabolic Alterations in Highly Tumorigenic Glioblastoma Cells

(2011) Yunfei Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Energy Metabolism in Human Pluripotent Stem Cells and Their Differentiated Counterparts

(2011) Sandra Varum et al.   PLoS One

Metabolic state of glioma stem cells and nontumorigenic cells

(2011) E. Vlashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oligomycin-induced Bioenergetic Adaptation in Cancer Cells with Heterogeneous Bioenergetic Organization

(2010) Wenshan Hao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human NARP Mitochondrial Mutation Metabolism Corrected With α-Ketoglutarate/Aspartate

(2009) Gianluca Sgarbi et al.   ARCHIVES OF NEUROLOGY

Succinyl-CoA Synthetase Is a Phosphate Target for the Activation of Mitochondrial Metabolism

(2009) Darci Phillips et al.   BIOCHEMISTRY

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Experimental assessment of bioenergetic differences caused by the common European mitochondrial DNA haplogroups H and T

(2008) Taku Amo et al.   GENE