Cancer stem cells in lung cancer: Evidence and controversies

Measurement of Aldehyde Dehydrogenase 1 Expression Defines a Group with Better Prognosis in Patients with Non-Small Cell Lung Cancer

(2012) Anastasios Dimou et al.   AMERICAN JOURNAL OF PATHOLOGY

Developmental signaling pathways in cancer stem cells of solid tumors

(2012) Christina Karamboulas et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Characterization of sphere-forming cells with stem-like properties from the small cell lung cancer cell line H446

(2012) Xiaofei Qiu et al.   CANCER LETTERS

Personalized Targeted Therapy for Lung Cancer

(2012) Kehua Wu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Aldehyde Dehydrogenase 1A1 Possesses Stem-Like Properties and Predicts Lung Cancer Patient Outcome

(2012) Xiao Li et al.   Journal of Thoracic Oncology

The Side Population in Human Lung Cancer Cell Line NCI-H460 Is Enriched in Stem-Like Cancer Cells

(2012) Yang Shi et al.   PLoS One

Mechanisms of Acquired Crizotinib Resistance in ALK-Rearranged Lung Cancers

(2012) R. Katayama et al.   Science Translational Medicine

Non-small cell lung cancer stem/progenitor cells are enriched in multiple distinct phenotypic subpopulations and exhibit plasticity

(2012) S Akunuru et al.   Cell Death & Disease

Prognostic significance of CD44s expression in resected non-small cell lung cancer

(2011) Yoon Ho Ko et al.   BMC CANCER

Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells

(2011) Piyush B. Gupta et al.   CELL

Eyes Wide Open: A Critical Review of Sphere-Formation as an Assay for Stem Cells

(2011) Erika Pastrana et al.   Cell Stem Cell

Effects of the Hedgehog pathway inhibitor GDC-0449 on lung cancer cell lines are mediated by side populations

(2011) Fei Tian et al.   CLINICAL AND EXPERIMENTAL MEDICINE

Notch1 loss of heterozygosity causes vascular tumors and lethal hemorrhage in mice

(2011) Zhenyi Liu et al.   JOURNAL OF CLINICAL INVESTIGATION

Notch Signaling Contributes to Lung Cancer Clonogenic Capacity In Vitro but May Be Circumvented in Tumorigenesis In Vivo

(2011) J. Osanyingbemi-Obidi et al.   MOLECULAR CANCER RESEARCH

A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia

(2011) Apostolos Klinakis et al.   NATURE

A crucial requirement for Hedgehog signaling in small cell lung cancer

(2011) Kwon-Sik Park et al.   NATURE MEDICINE

Rac1 Targeting Suppresses Human Non-Small Cell Lung Adenocarcinoma Cancer Stem Cell Activity

(2011) Shailaja Akunuru et al.   PLoS One

Aldehyde Dehydrogenase Activity Selects for Lung Adenocarcinoma Stem Cells Dependent on Notch Signaling

(2010) J. P. Sullivan et al.   CANCER RESEARCH

Tumor-Initiating Cells Are Rare in Many Human Tumors

(2010) Kota Ishizawa et al.   Cell Stem Cell

Controversies in Cancer Stem Cells: Targeting Embryonic Signaling Pathways

(2010) N. Takebe et al.   CLINICAL CANCER RESEARCH

Notch Signaling in the Immune System

(2010) Freddy Radtke et al.   IMMUNITY

Non-Small Cell Lung Cancer Cells Expressing CD44 Are Enriched for Stem Cell-Like Properties

(2010) Elaine Lai-Han Leung et al.   PLoS One

Local recurrence after surgery for early stage lung cancer

(2009) Chris R. Kelsey et al.   CANCER

Both CD133+and CD133−subpopulations of A549 and H446 cells contain cancer-initiating cells

(2009) Xiangjiao Meng et al.   CANCER SCIENCE

Angiogenesis: A Team Effort Coordinated by Notch

(2009) L.-K. Phng et al.   DEVELOPMENTAL CELL

Aldehyde Dehydrogenase 1 Is a Tumor Stem Cell-Associated Marker in Lung Cancer

(2009) F. Jiang et al.   MOLECULAR CANCER RESEARCH

Alterations of the Notch pathway in lung cancer

(2009) Britta Westhoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment

(2009) G. Bertolini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aldehyde dehydrogenase activity as a functional marker for lung cancer

(2008) Deniz Ucar et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Therapeutic Potential of γ -Secretase Inhibitors and Modulators

(2008) Bruno Imbimbo   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Hedgehog: functions and mechanisms

(2008) M. Varjosalo et al.   GENES & DEVELOPMENT

ALDH isozymes downregulation affects cell growth, cell motility and gene expression in lung cancer cells

(2008) Jan S Moreb et al.   Molecular Cancer

Identification of cells initiating human melanomas

(2008) Tobias Schatton et al.   NATURE

Efficient tumour formation by single human melanoma cells

(2008) Elsa Quintana et al.   NATURE

Drug-Selected Human Lung Cancer Stem Cells: Cytokine Network, Tumorigenic and Metastatic Properties

(2008) Vera Levina et al.   PLoS One

Oct-4 Expression Maintained Cancer Stem-Like Properties in Lung Cancer-Derived CD133-Positive Cells

(2008) Yu-Chih Chen et al.   PLoS One

Aldehyde Dehydrogenase as a Marker for Stem Cells

(2008) Jan Moreb   Current Stem Cell Research & Therapy