Conditional Deletion of Fgfr1 in the Proximal and Distal Tubule Identifies Distinct Roles in Phosphate and Calcium Transport

Osteocyte-Specific Deletion of Fgfr1 Suppresses FGF23

(2014) Zhousheng Xiao et al.   PLoS One

Calcium Regulates FGF-23 Expression in Bone

(2013) Valentin David et al.   ENDOCRINOLOGY

FGF23 acts directly on renal proximal tubules to induce phosphaturia through activation of the ERK1/2–SGK1 signaling pathway

(2012) Olena Andrukhova et al.   BONE

Targeted Deletion of Klotho in Kidney Distal Tubule Disrupts Mineral Metabolism

(2012) H. Olauson et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A Comparative Transcriptome Analysis Identifying FGF23 Regulated Genes in the Kidney of a Mouse CKD Model

(2012) Bing Dai et al.   PLoS One

Fibroblast Growth Factor 23 (FGF23) and Alpha-Klotho Stimulate Osteoblastic MC3T3.E1 Cell Proliferation and Inhibit Mineralization

(2011) V. Shalhoub et al.   CALCIFIED TISSUE INTERNATIONAL

Conditional deletion of Pkd1 in osteocytes disrupts skeletal mechanosensing in mice

(2011) Zhousheng Xiao et al.   FASEB JOURNAL

Klotho Inhibits Transforming Growth Factor-β1 (TGF-β1) Signaling and Suppresses Renal Fibrosis and Cancer Metastasis in Mice

(2011) Shigehiro Doi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

'Dem bones' are made for more than walking

(2011) L Darryl Quarles   NATURE MEDICINE

Compound deletion of Fgfr3 and Fgfr4 partially rescues the Hyp mouse phenotype

(2010) Hua Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Fibroblast Growth Factor Receptor Signaling Dramatically Accelerates Tumorigenesis and Enhances Oncoprotein Translation in the Mouse Mammary Tumor Virus–Wnt-1 Mouse Model of Breast Cancer

(2010) Adam C. Pond et al.   CANCER RESEARCH

Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule

(2010) Ming Chang Hu et al.   FASEB JOURNAL

Initial FGF23-Mediated Signaling Occurs in the Distal Convoluted Tubule

(2009) E. G. Farrow et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Regulation of phosphate transport by fibroblast growth factor 23 (FGF23): implications for disorders of phosphate metabolism

(2009) Jyothsna Gattineni et al.   PEDIATRIC NEPHROLOGY

Anti-FGF23 Neutralizing Antibodies Show the Physiological Role and Structural Features of FGF23

(2008) Yuji Yamazaki et al.   JOURNAL OF BONE AND MINERAL RESEARCH

FGFR3 and FGFR4 Do not Mediate Renal Effects of FGF23

(2008) S. Liu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

βKlotho Is Required for Fibroblast Growth Factor (FGF) 21 Signaling through FGF Receptor (FGFR) 1c and FGFR3c

(2008) Masashi Suzuki et al.   MOLECULAR ENDOCRINOLOGY