Iron Chelation Inhibits Osteoclastic Differentiation In Vitro and in Tg2576 Mouse Model of Alzheimer’s Disease

Iron overload causes osteoporosis in thalassemia major patients through interaction with transient receptor potential vanilloid type 1 (TRPV1) channels

(2014) F. Rossi et al.   HAEMATOLOGICA

Exogenous BMP7 corrects plasma iron overload and bone loss in Bmp6-/- mice

(2014) Martina Pauk et al.   INTERNATIONAL ORTHOPAEDICS

Tmem64 Modulates Calcium Signaling during RANKL-Mediated Osteoclast Differentiation

(2013) Hyunsoo Kim et al.   Cell Metabolism

Swedish mutant APP suppresses osteoblast differentiation and causes osteoporotic deficit, which are ameliorated by N-acetyl-L-cysteine

(2013) Wen-Fang Xia et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Bone remodelling is reduced by recovery from iron-deficiency anaemia in premenopausal women

(2013) Ione Wright et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Metallostasis in Alzheimer's disease

(2012) Scott Ayton et al.   FREE RADICAL BIOLOGY AND MEDICINE

The R740S mutation in the V-ATPase a3 subunit increases lysosomal pH, impairs NFATc1 translocation, and decreases in vitro osteoclastogenesis

(2012) Irina Voronov et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Ferric ion could facilitate osteoclast differentiation and bone resorption through the production of reactive oxygen species

(2012) Peng Jia et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export

(2012) Peng Lei et al.   NATURE MEDICINE

Osteoporosis: now and the future

(2011) Tilman D Rachner et al.   LANCET

Hepcidin and Ferroportin: The New Players in Iron Metabolism

(2011) Ivana De Domenico et al.   SEMINARS IN LIVER DISEASE

Bone loss caused by iron overload in a murine model: importance of oxidative stress

(2010) J. Tsay et al.   BLOOD

Iron-Export Ferroxidase Activity of β-Amyloid Precursor Protein Is Inhibited by Zinc in Alzheimer's Disease

(2010) James A. Duce et al.   CELL

APPswe/Aβ regulation of osteoclast activation and RAGE expression in an age-dependent manner

(2010) Shun Cui et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Specific iron chelators determine the route of ferritin degradation

(2009) I. De Domenico et al.   BLOOD

Osteoclasts Pump Iron

(2009) G. David Roodman   Cell Metabolism

Coordination of PGC-1β and iron uptake in mitochondrial biogenesis and osteoclast activation

(2009) Kiyo-aki Ishii et al.   NATURE MEDICINE

Alzheimer's disease, metal ions and metal homeostatic therapy

(2009) Paolo Zatta et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

HMGB1 Regulates RANKL-Induced Osteoclastogenesis in a Manner Dependent on RAGE

(2008) Zheng Zhou et al.   JOURNAL OF BONE AND MINERAL RESEARCH