The R740S mutation in the V-ATPase a3 subunit increases lysosomal pH, impairs NFATc1 translocation, and decreases in vitro osteoclastogenesis
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Title
The R740S mutation in the V-ATPase a3 subunit increases lysosomal pH, impairs NFATc1 translocation, and decreases in vitro osteoclastogenesis
Authors
Keywords
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Journal
JOURNAL OF BONE AND MINERAL RESEARCH
Volume 28, Issue 1, Pages 108-118
Publisher
Wiley
Online
2012-08-04
DOI
10.1002/jbmr.1727
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- Bone marrow microenvironment controls the in vivo differentiation of murine dendritic cells into osteoclasts
- (2008) A. Wakkach et al. BLOOD
- Infantile Malignant, Autosomal Recessive Osteopetrosis: The Rich and The Poor
- (2008) Anna Villa et al. CALCIFIED TISSUE INTERNATIONAL
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