Bortezomib Plus Continuous B Cell Depletion Results in Sustained Plasma Cell Depletion and Amelioration of Lupus Nephritis in NZB/W F1 Mice
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Title
Bortezomib Plus Continuous B Cell Depletion Results in Sustained Plasma Cell Depletion and Amelioration of Lupus Nephritis in NZB/W F1 Mice
Authors
Keywords
Plasma cells, B cells, Bone marrow cells, Enzyme-linked immunoassays, Spleen, Cloning, Flow cytometry, Systemic lupus erythematosus
Journal
PLoS One
Volume 10, Issue 8, Pages e0135081
Publisher
Public Library of Science (PLoS)
Online
2015-08-08
DOI
10.1371/journal.pone.0135081
References
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- Bone marrow of NZB/W mice is the major site for plasma cells resistant to dexamethasone and cyclophosphamide: Implications for the treatment of autoimmunity
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- Protective and Pathogenic Roles for B Cells during Systemic Autoimmunity in NZB/W F1 Mice
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- Rituximab specifically depletes short-lived autoreactive plasma cells in a mouse model of inflammatory arthritis
- (2010) H. Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HLA-DRhigh/CD27high plasmablasts indicate active disease in patients with systemic lupus erythematosus
- (2009) A M Jacobi et al. ANNALS OF THE RHEUMATIC DISEASES
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- (2008) T. Alexander et al. BLOOD
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- (2008) Kirsten Neubert et al. NATURE MEDICINE
- Maintenance of the plasma cell pool is independent of memory B cells
- (2008) A. Ahuja et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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