Activation of GPR55 Receptors Exacerbates oxLDL-Induced Lipid Accumulation and Inflammatory Responses, while Reducing Cholesterol Efflux from Human Macrophages

Endomorphin-1 Inhibits the Activation and the Development of a Hyporesponsive-like Phenotype in Lipopolysaccharide-Stimulated THP-1 Monocytes

(2017) V. Izzi et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Detailed characterization of the endocannabinoid system in human macrophages and foam cells, and anti-inflammatory role of type-2 cannabinoid receptor

(2014) Valerio Chiurchiù et al.   ATHEROSCLEROSIS

Interleukin-10 increases reverse cholesterol transport in macrophages through its bidirectional interaction with liver X receptor α

(2014) Bente Halvorsen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The differential characterization of GPR55 receptor in human peripheral blood reveals a distinctive expression in monocytes and NK cells and a proinflammatory role in these innate cells

(2014) Valerio Chiurchiù et al.   INTERNATIONAL IMMUNOLOGY

Distinct modulation of human myeloid and plasmacytoid dendritic cells by anandamide in multiple sclerosis

(2013) Valerio Chiurchiù et al.   ANNALS OF NEUROLOGY

Evaluation of the insulin releasing and antihyperglycaemic activities of GPR55 lipid agonists using clonal beta-cells, isolated pancreatic islets and mice

(2013) A M McKillop et al.   BRITISH JOURNAL OF PHARMACOLOGY

Effect of IL-10 on LOX-1 expression, signalling and functional activity: An atheroprotective response

(2013) Albina Arjuman et al.   Diabetes & Vascular Disease Research

A potential role for GPR55 in the regulation of energy homeostasis

(2013) Anna C. Simcocks et al.   DRUG DISCOVERY TODAY

A role for O-1602 and G protein-coupled receptor GPR55 in the control of colonic motility in mice

(2013) Kun Li et al.   NEUROPHARMACOLOGY

Cannabinoid- and lysophosphatidylinositol-sensitive receptor GPR55 boosts neurotransmitter release at central synapses

(2013) S. Sylantyev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NFAT control of innate immunity

(2012) J. Fric et al.   BLOOD

Targeting cannabinoid receptor CB2 in cardiovascular disorders: promises and controversies

(2012) Sabine Steffens et al.   BRITISH JOURNAL OF PHARMACOLOGY

Endocannabinoids inhibit release of nerve growth factor by inflammation-activated mast cells

(2011) Giuseppina Cantarella et al.   BIOCHEMICAL PHARMACOLOGY

GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils

(2011) Nariman A B Balenga et al.   CELL RESEARCH

The L- -Lysophosphatidylinositol/GPR55 System and Its Potential Role in Human Obesity

(2011) J. M. Moreno-Navarrete et al.   DIABETES

The atypical cannabinoid O-1602 stimulates food intake and adiposity in rats

(2011) A. Díaz-Arteaga et al.   DIABETES OBESITY & METABOLISM

A role for the putative cannabinoid receptor GPR55 in the islets of Langerhans

(2011) Silvana Y Romero-Zerbo et al.   JOURNAL OF ENDOCRINOLOGY

Atheroprotection via cannabinoid receptor-2 is mediated by circulating and vascular cells in vivo

(2011) Friedrich Felix Hoyer et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cannabinoid receptor type 2 (CB2) deficiency alters atherosclerotic lesion formation in hyperlipidemic Ldlr-null mice

(2010) Courtney D. Netherland et al.   ATHEROSCLEROSIS

Endocannabinoid-like N-arachidonoyl serine is a novel pro-angiogenic mediator

(2010) X Zhang et al.   BRITISH JOURNAL OF PHARMACOLOGY

GPR55-dependent and -independent ion signalling in response to lysophosphatidylinositol in endothelial cells

(2010) Alexander Bondarenko et al.   BRITISH JOURNAL OF PHARMACOLOGY

Endomorphin-1 prevents lipid accumulation via CD36 down-regulation and modulates cytokines release from human lipid-laden macrophages

(2010) Valerio Chiurchiù et al.   PEPTIDES

Pharmacological characterization of GPR55, a putative cannabinoid receptor

(2010) Haleli Sharir et al.   PHARMACOLOGY & THERAPEUTICS

Anandamide Suppresses Proliferation and Cytokine Release from Primary Human T-Lymphocytes Mainly via CB2 Receptors

(2010) Maria Teresa Cencioni et al.   PLoS One

ABCG1 mediated oxidized LDL-derived oxysterol efflux from macrophages

(2009) Mingzhi Xu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Statins inhibit cyclooxygenase-2 and matrix metalloproteinase-9 in human endothelial cells: anti-angiogenic actions possibly contributing to plaque stability

(2009) Marika Massaro et al.   CARDIOVASCULAR RESEARCH

Regulation of MAP Kinase-Directed Mitogenic and Protein Kinase B-Mediated Signaling by Cannabinoid Receptor Type 1 in Skeletal Muscle Cells

(2009) C. Lipina et al.   DIABETES

The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo

(2009) L. S. Whyte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The enigmatic pharmacology of GPR55

(2009) Ruth A. Ross   TRENDS IN PHARMACOLOGICAL SCIENCES

Rimonabant, a Selective Cannabinoid CB1 Receptor Antagonist, Inhibits Atherosclerosis in LDL Receptor–Deficient Mice

(2008) Frédérique Dol-Gleizes et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cannabinoid CB 1 Receptor Antagonists for Atherosclerosis and Cardiometabolic Disorders

(2008) Pál Pacher   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The GPR55 ligand l-α-lysophosphatidylinositol promotes RhoA-dependent Ca2+ signaling and NFAT activation

(2008) Christopher M. Henstridge et al.   FASEB JOURNAL

Integrin clustering enables anandamide-induced Ca2+ signaling in endothelial cells via GPR55 by protection against CB1-receptor-triggered repression

(2008) M. Waldeck-Weiermair et al.   JOURNAL OF CELL SCIENCE

The Role of the Endocannabinoid System in Atherosclerosis

(2008) F. Mach et al.   JOURNAL OF NEUROENDOCRINOLOGY

The putative cannabinoid receptor GPR55 plays a role in mechanical hyperalgesia associated with inflammatory and neuropathic pain

(2008) Penny C. Staton et al.   PAIN

Brain Natriuretic Peptide (BNP) regulates the production of inflammatory mediators in human THP-1 macrophages

(2008) V. Chiurchiù et al.   REGULATORY PEPTIDES