Comprehensive Analysis of Glycolytic Enzymes as Therapeutic Targets in the Treatment of Glioblastoma

KEGG-PATH: Kyoto encyclopedia of genes and genomes-based pathway analysis using a path analysis model

(2014) Junli Du et al.   Molecular BioSystems

A Randomized Trial of Bevacizumab for Newly Diagnosed Glioblastoma

(2014) Mark R. Gilbert et al.   NEW ENGLAND JOURNAL OF MEDICINE

U-251 revisited: genetic drift and phenotypic consequences of long-term cultures of glioblastoma cells

(2014) Anja Torsvik et al.   Cancer Medicine

Hypoxia and oxygenation induce a metabolic switch between pentose phosphate pathway and glycolysis in glioma stem-like cells

(2013) Annegret Kathagen et al.   ACTA NEUROPATHOLOGICA

Side population in human glioblastoma is non-tumorigenic and characterizes brain endothelial cells

(2013) Anna Golebiewska et al.   BRAIN

Combined Targeting of PDK1 and EGFR Triggers Regression of Glioblastoma by Reversing the Warburg Effect

(2013) K. K. Velpula et al.   CANCER RESEARCH

Dichloroacetate reverses the hypoxic adaptation to bevacizumab and enhances its antitumor effects in mouse xenografts

(2013) Krishan Kumar et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Pyruvate dehydrogenase kinase as a novel therapeutic target in oncology

(2013) Gopinath Sutendra et al.   Frontiers in Oncology

Tumor angiogenesis and anti-angiogenic therapy in malignant gliomas revisited

(2012) Karl H. Plate et al.   ACTA NEUROPATHOLOGICA

Correlation of expression levels of ANXA2, PGAM1, and CALR with glioma grade and prognosis

(2012) Huasong Gao et al.   JOURNAL OF NEUROSURGERY

Passenger deletions generate therapeutic vulnerabilities in cancer

(2012) Florian L. Muller et al.   NATURE

Standards of care for treatment of recurrent glioblastoma—are we there yet?

(2012) Michael Weller et al.   NEURO-ONCOLOGY

Neuronal markers are expressed in human gliomas and NSE knockdown sensitizes glioblastoma cells to radiotherapy and temozolomide

(2011) Tao Yan et al.   BMC CANCER

Novel ways to target brain tumour metabolism

(2011) Daniel Stieber et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Hexokinase 2 is a key mediator of aerobic glycolysis and promotes tumor growth in human glioblastoma multiforme

(2011) Amparo Wolf et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases

(2011) Peter Carmeliet et al.   NATURE REVIEWS DRUG DISCOVERY

Developmental profile and regulation of the glycolytic enzyme hexokinase 2 in normal brain and glioblastoma multiforme

(2011) Amparo Wolf et al.   NEUROBIOLOGY OF DISEASE

RNAi screening in glioma stem-like cells identifies PFKFB4 as a key molecule important for cancer cell survival

(2011) V Goidts et al.   ONCOGENE

REVIGO Summarizes and Visualizes Long Lists of Gene Ontology Terms

(2011) Fran Supek et al.   PLoS One

Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma

(2011) Olivier Keunen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clotrimazole potentiates the inhibitory effects of ATP on the key glycolytic enzyme 6-phosphofructo-1-kinase

(2010) Mariah Celestino Marcondes et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Differentiation Therapy Exerts Antitumor Effects on Stem-like Glioma Cells

(2010) B. Campos et al.   CLINICAL CANCER RESEARCH

3-Bromopyruvate: A New Targeted Antiglycolytic Agent and a Promise for Cancer Therapy

(2010) S. Ganapathy-Kanniappan et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Multicellular tumor spheroids: An underestimated tool is catching up again

(2010) Franziska Hirschhaeuser et al.   JOURNAL OF BIOTECHNOLOGY

Quantitative proteomics identification of phosphoglycerate mutase 1 as a novel therapeutic target in hepatocellular carcinoma

(2010) Fenglian Ren et al.   Molecular Cancer

Metabolic Modulation of Glioblastoma with Dichloroacetate

(2010) E. D. Michelakis et al.   Science Translational Medicine

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

A novel eGFP-expressing immunodeficient mouse model to study tumor-host interactions

(2008) Simone P. Niclou et al.   FASEB JOURNAL

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

(2008) Heather R. Christofk et al.   NATURE

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH