Pharmacokinetics, pharmacodynamics, and pharmacogenetics of hydroxyurea treatment for children with sickle cell anemia

National Institutes of Health Consensus Development Conference Statement: Hydroxyurea Treatment for Sickle Cell Disease

(2013) Otis W. Brawley   ANNALS OF INTERNAL MEDICINE

Chromosome damage and repair in children with sickle cell anaemia and long-term hydroxycarbamide exposure

(2011) Patrick T. McGann et al.   BRITISH JOURNAL OF HAEMATOLOGY

Hydroxyurea for sickle cell anemia: what have we learned and what questions still remain?

(2011) Patrick T McGann et al.   CURRENT OPINION IN HEMATOLOGY

Hydroxycarbamide in very young children with sickle-cell anaemia: a multicentre, randomised, controlled trial (BABY HUG)

(2011) Winfred C Wang et al.   LANCET

Glomerular hyperfiltration and albuminuria in children with sickle cell anemia

(2011) Banu Aygun et al.   PEDIATRIC NEPHROLOGY

How I use hydroxyurea to treat young patients with sickle cell anemia

(2010) R. E. Ware   BLOOD

Thein VivoToxicity of Hydroxyurea Depends on Its Direct Target Catalase

(2010) Trine Juul et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Assessment of genotoxicity associated with hydroxyurea therapy in children with sickle cell anemia

(2010) Jonathan M. Flanagan et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

The effect of prolonged administration of hydroxyurea on morbidity and mortality in adult patients with sickle cell syndromes: results of a 17-year, single-center trial (LaSHS)

(2009) E. Voskaridou et al.   BLOOD

Hydroxyurea in sickle cell disease—A study of clinico-pharmacological efficacy in the Indian haplotype

(2008) K ITALIA et al.   BLOOD CELLS MOLECULES AND DISEASES

Hydroxyurea for Children with Sickle Cell Disease

(2008) Matthew M. Heeney et al.   PEDIATRIC CLINICS OF NORTH AMERICA

CHEMICAL AND FUNCTIONAL ANALYSIS OF GENERIC HYDROXYUREA FORMULATIONS

(2008) Virginia L. Harrod et al.   PEDIATRIC HEMATOLOGY AND ONCOLOGY

DNA polymorphisms at the BCL11A, HBS1L-MYB, and  -globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease

(2008) G. Lettre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA