The Application of the Open Pharmacological Concepts Triple Store (Open PHACTS) to Support Drug Discovery Research

The Role of the Innate Immune System in Alzheimer’s Disease and Frontotemporal Lobar Degeneration: An Eye on Microglia

(2013) Elisa Ridolfi et al.   Clinical & Developmental Immunology

Scientific competency questions as the basis for semantically enriched open pharmacological space development

(2013) Kamal Azzaoui et al.   DRUG DISCOVERY TODAY

Structural basis for vitamin D receptor agonism by novel non-secosteroidal ligands

(2013) Lisa Asano et al.   FEBS LETTERS

The ChEMBL bioactivity database: an update

(2013) A. Patrícia Bento et al.   NUCLEIC ACIDS RESEARCH

Open PHACTS: semantic interoperability for drug discovery

(2012) Antony J. Williams et al.   DRUG DISCOVERY TODAY

24-Hydroxylase in cancer: Impact on vitamin D-based anticancer therapeutics

(2012) Wei Luo et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

The ChEBI reference database and ontology for biologically relevant chemistry: enhancements for 2013

(2012) Janna Hastings et al.   NUCLEIC ACIDS RESEARCH

Identifying mechanism-of-action targets for drugs and probes

(2012) E. Gregori-Puigjane et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

25-Hydroxyvitamin D-24-hydroxylase (CYP24A1): Its important role in the degradation of vitamin D

(2011) Glenville Jones et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

WikiPathways: building research communities on biological pathways

(2011) T. Kelder et al.   NUCLEIC ACIDS RESEARCH

ChEMBL: a large-scale bioactivity database for drug discovery

(2011) A. Gaulton et al.   NUCLEIC ACIDS RESEARCH

The Physiology, Signaling, and Pharmacology of Dopamine Receptors

(2011) J.-M. Beaulieu et al.   PHARMACOLOGICAL REVIEWS

Linked open drug data for pharmaceutical research and development

(2011) Matthias Samwald et al.   Journal of Cheminformatics

Chem2Bio2RDF: a semantic framework for linking and data mining chemogenomic and systems chemical biology data

(2010) Bin Chen et al.   BMC BIOINFORMATICS

The transcription factors Snail1 and Snail2 repress vitamin D receptor during colon cancer progression

(2010) María Jesús Larriba et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

DrugBank 3.0: a comprehensive resource for 'Omics' research on drugs

(2010) C. Knox et al.   NUCLEIC ACIDS RESEARCH

Novel Snail1 Target Proteins in Human Colon Cancer Identified by Proteomic Analysis

(2010) María Jesús Larriba et al.   PLoS One

Collaborative development of predictive toxicology applications

(2010) Barry Hardy et al.   Journal of Cheminformatics

ChemSpider - building a foundation for the semantic web by hosting a crowd sourced databasing platform for chemistry

(2010) Anthony J Williams et al.   Journal of Cheminformatics

Synthesis of 2α-propoxy-1α,25-dihydroxyvitamin D3 and comparison of its metabolism by human CYP24A1 and rat CYP24A1

(2009) Nozomi Saito et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Snail2 cooperates with Snail1 in the repression of vitamin D receptor in colon cancer

(2009) M. J. Larriba et al.   CARCINOGENESIS

Predicting new molecular targets for known drugs

(2009) Michael J. Keiser et al.   NATURE

Chemical Entities of Biological Interest: an update

(2009) Paula de Matos et al.   NUCLEIC ACIDS RESEARCH

Gene Ontology annotations: what they mean and where they come from

(2008) David P Hill et al.   BMC BIOINFORMATICS

Bio2RDF: Towards a mashup to build bioinformatics knowledge systems

(2008) François Belleau et al.   JOURNAL OF BIOMEDICAL INFORMATICS

Molecular actions of vitamin D contributing to cancer prevention

(2008) James C. Fleet   MOLECULAR ASPECTS OF MEDICINE

Vitamin D analogs: Therapeutic applications and mechanisms for selectivity

(2008) Alex J. Brown et al.   MOLECULAR ASPECTS OF MEDICINE