Investigating the Molecular Basis of Siah1 and Siah2 E3 Ubiquitin Ligase Substrate Specificity
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Title
Investigating the Molecular Basis of Siah1 and Siah2 E3 Ubiquitin Ligase Substrate Specificity
Authors
Keywords
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Journal
PLoS One
Volume 9, Issue 9, Pages e106547
Publisher
Public Library of Science (PLoS)
Online
2014-09-10
DOI
10.1371/journal.pone.0106547
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Note: Only part of the references are listed.- The E3 Ubiquitin Ligase Siah2 Contributes to Castration-Resistant Prostate Cancer by Regulation of Androgen Receptor Transcriptional Activity
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- Structure-Based Design of Covalent Siah Inhibitors
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- Vascular Normalization by Loss of Siah2 Results in Increased Chemotherapeutic Efficacy
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- Nuclear accumulation of seven in absentia homologue-2 supports motility and proliferation of liver cancer cells
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- (2012) Min Liu et al. MOLECULAR CELL
- SIAH ubiquitin ligases target the nonreceptor tyrosine kinase ACK1 for ubiquitinylation and proteasomal degradation
- (2012) M Buchwald et al. ONCOGENE
- Identification of a Src Tyrosine Kinase/SIAH2 E3 Ubiquitin Ligase Pathway That Regulates C/EBP Expression and Contributes to Transformation of Breast Tumor Cells
- (2011) T. R. Sarkar et al. MOLECULAR AND CELLULAR BIOLOGY
- Increased SIAH expression predicts ductal carcinoma in situ (DCIS) progression to invasive carcinoma
- (2010) Kathryn C. Behling et al. BREAST CANCER RESEARCH AND TREATMENT
- Siah2-Dependent Concerted Activity of HIF and FoxA2 Regulates Formation of Neuroendocrine Phenotype and Neuroendocrine Prostate Tumors
- (2010) Jianfei Qi et al. CANCER CELL
- RING Domain E3 Ubiquitin Ligases
- (2009) Raymond J. Deshaies et al. Annual Review of Biochemistry
- Siah Proteins: Novel Drug Targets in the Ras and Hypoxia Pathways
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- The Ubiquitin Ligase Siah2 and the Hypoxia Response
- (2009) K. Nakayama et al. MOLECULAR CANCER RESEARCH
- Alterations of ubiquitin ligases in human cancer and their association with the natural history of the tumor
- (2009) S Confalonieri et al. ONCOGENE
- Inhibition of Siah2 ubiquitin ligase by vitamin K3 (menadione) attenuates hypoxia and MAPK signaling and blocks melanoma tumorigenesis
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- Effect of Disrupting Seven-in-Absentia Homolog 2 Function on Lung Cancer Cell Growth
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- The ubiquitin ligase Siah2 regulates tumorigenesis and metastasis by HIF-dependent and -independent pathways
- (2008) J. Qi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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