Identification of a Src Tyrosine Kinase/SIAH2 E3 Ubiquitin Ligase Pathway That Regulates C/EBP  Expression and Contributes to Transformation of Breast Tumor Cells

Combating trastuzumab resistance by targeting SRC, a common node downstream of multiple resistance pathways

(2011) Siyuan Zhang et al.   NATURE MEDICINE

Down-Regulation of the Oncogene Cyclin D1 Increases Migratory Capacity in Breast Cancer and Is Linked to Unfavorable Prognostic Features

(2010) Sophie Lehn et al.   AMERICAN JOURNAL OF PATHOLOGY

SUMO and ubiquitin paths converge

(2010) Amanda Denuc et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Cyclin D1/Cyclin-Dependent Kinase 4 Interacts with Filamin A and Affects the Migration and Invasion Potential of Breast Cancer Cells

(2010) Z. Zhong et al.   CANCER RESEARCH

The tumour suppressor C/EBPδ inhibits FBXW7 expression and promotes mammary tumour metastasis

(2010) Kuppusamy Balamurugan et al.   EMBO JOURNAL

Control of mammary tumor differentiation by SKI-606 (bosutinib)

(2010) L Hebbard et al.   ONCOGENE

CCAAT/enhancer binding protein delta (C/EBP , CEBPD)-mediated nuclear import of FANCD2 by IPO4 augments cellular response to DNA damage

(2010) J. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The ubiquitin ligase Fbxw7 controls adipocyte differentiation by targeting C/EBP  for degradation

(2010) M. T. Bengoechea-Alonso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

C/EBP  targets cyclin D1 for proteasome-mediated degradation via induction of CDC27/APC3 expression

(2010) S. A. Pawar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Locking Src/Abl Tyrosine Kinase Activities Regulate Cell Differentiation and Invasion of Human Cervical Cancer Cells Expressing E6/E7 Oncoproteins of High-Risk HPV

(2010) Amber Yasmeen et al.   Journal of Oncology

Siah Proteins: Novel Drug Targets in the Ras and Hypoxia Pathways

(2009) C. M. House et al.   CANCER RESEARCH

Activation of Src by Protein Tyrosine Phosphatase 1B Is Required for ErbB2 Transformation of Human Breast Epithelial Cells

(2009) L. E. Arias-Romero et al.   CANCER RESEARCH

SRC kinase inhibition: Targeting bone metastases and tumor growth in prostate and breast cancer

(2009) Fred Saad et al.   CANCER TREATMENT REVIEWS

Nuclear cyclin D1: An oncogenic driver in human cancer

(2009) Jong Kyong Kim et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The cell growth inhibitory transcription factor C/EBPδ is expressed in human meningiomas in association with low histological grade and proliferation index

(2009) V. Barresi et al.   JOURNAL OF NEURO-ONCOLOGY

Src kinases as therapeutic targets for cancer

(2009) Lori C. Kim et al.   Nature Reviews Clinical Oncology

The Role of Src in Solid Tumors

(2009) D. L. Wheeler et al.   ONCOLOGIST

Targeting Src in breast cancer

(2008) R. S. Finn   ANNALS OF ONCOLOGY

Epigenetic Silencing of CCAAT/Enhancer-binding Protein δ Activity by YY1/Polycomb Group/DNA Methyltransferase Complex

(2008) Chiung-Yuan Ko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alternate Cyclin D1 mRNA Splicing Modulates p27KIP1Binding and Cell Migration

(2008) Zhiping Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effect of Disrupting Seven-in-Absentia Homolog 2 Function on Lung Cancer Cell Growth

(2008) Atique U. Ahmed et al.   JNCI-Journal of the National Cancer Institute

SKI-606 (bosutinib), a novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells

(2008) A. Vultur et al.   MOLECULAR CANCER THERAPEUTICS

The ubiquitin ligase Siah2 regulates tumorigenesis and metastasis by HIF-dependent and -independent pathways

(2008) J. Qi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA