Targeting Catalase but Not Peroxiredoxins Enhances Arsenic Trioxide-Induced Apoptosis in K562 Cells

Alantolactone induces apoptosis in chronic myelogenous leukemia sensitive or resistant to imatinib through NF-κB inhibition and Bcr/Abl protein deletion

(2013) Wei Wei et al.   APOPTOSIS

Autophagic degradation of the BCR-ABL oncoprotein and generation of antileukemic responses by arsenic trioxide

(2012) D. J. Goussetis et al.   BLOOD

Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling

(2012) Paul D. Ray et al.   CELLULAR SIGNALLING

Targeting peroxiredoxins against leukemia

(2012) Chuan-Xu Liu et al.   EXPERIMENTAL CELL RESEARCH

Peroxiredoxins, gerontogenes linking aging to genome instability and cancer

(2012) T. Nystrom et al.   GENES & DEVELOPMENT

Adenanthin targets peroxiredoxin I and II to induce differentiation of leukemic cells

(2012) Chuan-Xu Liu et al.   Nature Chemical Biology

Activation of stress response gene SIRT1 by BCR-ABL promotes leukemogenesis

(2011) H. Yuan et al.   BLOOD

Genome-wide analysis of histone H3 acetylation patterns in AML identifies PRDX2 as an epigenetically silenced tumor suppressor gene

(2011) S. Agrawal-Singh et al.   BLOOD

Curing APL through PML/RARA degradation by As2O3

(2011) Valerie Lallemand-Breitenbach et al.   TRENDS IN MOLECULAR MEDICINE

PML/RARA Oxidation and Arsenic Binding Initiate the Antileukemia Response of As2O3

(2010) Marion Jeanne et al.   CANCER CELL

Thein VivoToxicity of Hydroxyurea Depends on Its Direct Target Catalase

(2010) Trine Juul et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Arsenic trioxide induces apoptosis through JNK and ERK in human mesothelioma cells

(2010) Ryoji Eguchi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Arsenic Trioxide Controls the Fate of the PML-RAR  Oncoprotein by Directly Binding PML

(2010) X. W. Zhang et al.   SCIENCE

Downregulation of thec-MYCtarget gene, peroxiredoxin III, contributes to arsenic trioxide-induced apoptosis in acute promyelocytic leukemia

(2009) Pablo E. Vivas-Mejía et al.   INTERNATIONAL JOURNAL OF CANCER

Acute promyelocytic leukemia: from highly fatal to highly curable

(2008) Z.-Y. Wang et al.   BLOOD

Inhibition on LS-174T cell growth and activity of telomerase in vitro and in vivo by arsenic trioxide

(2008) Xishan Wang et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Catalase activity and arsenic sensitivity in acute leukemia

(2008) Emma Coe et al.   LEUKEMIA & LYMPHOMA