Activation of stress response gene SIRT1 by BCR-ABL promotes leukemogenesis

JNK2-dependent regulation of SIRT1 protein stability

(2011) Jack Ford et al.   CELL CYCLE

Human chronic myeloid leukemia stem cells are insensitive to imatinib despite inhibition of BCR-ABL activity

(2010) Amie S. Corbin et al.   JOURNAL OF CLINICAL INVESTIGATION

NAMPT overexpression in prostate cancer and its contribution to tumor cell survival and stress response

(2010) B Wang et al.   ONCOGENE

BCR-ABLGene Expression Is Required for Its Mutations in a Novel KCL-22 Cell Culture Model for Acquired Resistance of Chronic Myelogenous Leukemia

(2009) Hongfeng Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A c-Myc–SIRT1 feedback loop regulates cell growth and transformation

(2009) Jian Yuan et al.   JOURNAL OF CELL BIOLOGY

SIRT1 histone deacetylase expression is associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer

(2009) Katsuhiko Nosho et al.   MODERN PATHOLOGY

SirT1-null mice develop tumors at normal rates but are poorly protected by resveratrol

(2009) G Boily et al.   ONCOGENE

SIRT1 Expression is Associated With Poor Prognosis of Diffuse Large B-Cell Lymphoma

(2008) Kyu Yun Jang et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Discovery, In Vivo Activity, and Mechanism of Action of a Small-Molecule p53 Activator

(2008) Sonia Lain et al.   CANCER CELL

Impaired DNA Damage Response, Genome Instability, and Tumorigenesis in SIRT1 Mutant Mice

(2008) Rui-Hong Wang et al.   CANCER CELL

SIRT1 Redistribution on Chromatin Promotes Genomic Stability but Alters Gene Expression during Aging

(2008) Philipp Oberdoerffer et al.   CELL

SirT1 Inhibition Reduces IGF-I/IRS-2/Ras/ERK1/2 Signaling and Protects Neurons

(2008) Ying Li et al.   Cell Metabolism

Interpretation of cytokine signaling through the transcription factors STAT5A and STAT5B

(2008) L. Hennighausen et al.   GENES & DEVELOPMENT

SIRT1 Acts as a Nutrient-sensitive Growth Suppressor and Its Loss Is Associated with Increased AMPK and Telomerase Activity

(2008) Swami R. Narala et al.   MOLECULAR BIOLOGY OF THE CELL

SirT1 Regulates Energy Metabolism and Response to Caloric Restriction in Mice

(2008) Gino Boily et al.   PLoS One