Amyloid-β and Proinflammatory Cytokines Utilize a Prion Protein-Dependent Pathway to Activate NADPH Oxidase and Induce Cofilin-Actin Rods in Hippocampal Neurons

Mapping Cofilin-Actin Rods in Stressed Hippocampal Slices and the Role of cdc42 in Amyloid-β-Induced Rods

(2017) Richard C. Davis et al.   JOURNAL OF ALZHEIMERS DISEASE

The role of inflammasome in Alzheimer's disease

(2014) Li Liu et al.   AGEING RESEARCH REVIEWS

A Genetically Encoded Reporter for Real-Time Imaging of Cofilin-Actin Rods in Living Neurons

(2014) Jianjie Mi et al.   PLoS One

Oxidative stress response elicited by mitochondrial dysfunction: Implication in the pathophysiology of aging

(2013) Chih-Hao Wang et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Mitochondrial dysfunction and calcium deregulation by the RanBP9-cofilin pathway

(2013) Seung-Eon Roh et al.   FASEB JOURNAL

Down’s syndrome, neuroinflammation, and Alzheimer neuropathogenesis

(2013) Donna M Wilcock et al.   Journal of Neuroinflammation

The association between the methionine/valine (M/V) polymorphism (rs1799990) in the PRNP gene and the risk of Alzheimer disease: An update by meta-analysis

(2013) Jie He et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Sporadic Alzheimer’s Disease Begins as Episodes of Brain Ischemia and Ischemically Dysregulated Alzheimer’s Disease Genes

(2013) Ryszard Pluta et al.   MOLECULAR NEUROBIOLOGY

Cytosolic phospholipase A2α upregulation mediates apoptotic neuronal death induced by aggregated amyloid-β peptide1–42

(2013) Chen Sagy-Bross et al.   NEUROCHEMISTRY INTERNATIONAL

Metabotropic Glutamate Receptor 5 Is a Coreceptor for Alzheimer Aβ Oligomer Bound to Cellular Prion Protein

(2013) Ji Won Um et al.   NEURON

Promiscuous Alzheimer's Amyloid: Yet Another Partner

(2013) I. Benilova et al.   SCIENCE

Human LilrB2 Is a  -Amyloid Receptor and Its Murine Homolog PirB Regulates Synaptic Plasticity in an Alzheimer's Model

(2013) T. Kim et al.   SCIENCE

The levels of water-soluble and triton-soluble Aβ are increased in Alzheimer's disease brain

(2012) Jessica M. McDonald et al.   BRAIN RESEARCH

Pivotal role of the RanBP9-cofilin pathway in Aβ-induced apoptosis and neurodegeneration

(2012) J A Woo et al.   CELL DEATH AND DIFFERENTIATION

Targeting NOX enzymes in the central nervous system: therapeutic opportunities

(2012) Silvia Sorce et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

L-threo-C6-pyridinium-ceramide Bromide, a Novel Cationic Ceramide, Induces NADPH Oxidase Activation, Mitochondrial Dysfunction and Loss in Cell Viability in INS 832/13 �-cells

(2012) Ismail Syed et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Neurodegeneration Induced by Clustering of Sialylated Glycosylphosphatidylinositols of Prion Proteins

(2012) Clive Bate et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Incorporation of Cofilin into Rods Depends on Disulfide Intermolecular Bonds: Implications for Actin Regulation and Neurodegenerative Disease

(2012) B. W. Bernstein et al.   JOURNAL OF NEUROSCIENCE

Role of Cholesterol in APP Metabolism and Its Significance in Alzheimer’s Disease Pathogenesis

(2012) M. Maulik et al.   MOLECULAR NEUROBIOLOGY

Brain Ischemia Activates β- and γ-Secretase Cleavage of Amyloid Precursor Protein: Significance in Sporadic Alzheimer’s Disease

(2012) Ryszard Pluta et al.   MOLECULAR NEUROBIOLOGY

A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline

(2012) Thorlakur Jonsson et al.   NATURE

Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons

(2012) Ji Won Um et al.   NATURE NEUROSCIENCE

Neuroinflammatory phenotype in early Alzheimer's disease

(2012) Tiffany L. Sudduth et al.   NEUROBIOLOGY OF AGING

Traumatic brain injury: A risk factor for Alzheimer's disease

(2012) Thamil Mani Sivanandam et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Overlapping profiles of Abeta peptides in the Alzheimer's disease and pathological aging brains

(2012) Brenda D Moore et al.   Alzheimers Research & Therapy

Ceramide kinase regulates TNFα-stimulated NADPH oxidase activity and eicosanoid biosynthesis in neuroblastoma cells

(2011) Brian M. Barth et al.   CELLULAR SIGNALLING

NADPH-oxidase activation and cognition in Alzheimer disease progression

(2011) Mubeen A. Ansari et al.   FREE RADICAL BIOLOGY AND MEDICINE

Amyloid-β-induced Synapse Damage Is Mediated via Cross-linkage of Cellular Prion Proteins

(2011) Clive Bate et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cofilin Aggregation Blocks Intracellular Trafficking and Induces Synaptic Loss in Hippocampal Neurons

(2011) Joseph Cichon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alzheimer's Disease Brain-Derived Amyloid- -Mediated Inhibition of LTP In Vivo Is Prevented by Immunotargeting Cellular Prion Protein

(2011) A. E. Barry et al.   JOURNAL OF NEUROSCIENCE

Amyloid beta dimers/trimers potently induce cofilin-actin rods that are inhibited by maintaining cofilin-phosphorylation

(2011) Richard C Davis et al.   Molecular Neurodegeneration

Cognitive impairment in humanized APP×PS1 mice is linked to Aβ1–42 and NOX activation

(2011) Annadora J. Bruce-Keller et al.   NEUROBIOLOGY OF DISEASE

Lipid raft disruption protects mature neurons against amyloid oligomer toxicity

(2010) Fiorella Malchiodi-Albedi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Anti-PrPC monoclonal antibody infusion as a novel treatment for cognitive deficits in an alzheimer's disease model mouse

(2010) Erika Chung et al.   BMC NEUROSCIENCE

The presence of sodium dodecyl sulphate-stable Aβ dimers is strongly associated with Alzheimer-type dementia

(2010) Jessica M. Mc Donald et al.   BRAIN

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

(2010) Lars M. Ittner et al.   CELL

ADF/Cofilin-Actin Rods in Neurodegenerative Diseases

(2010) J.R. Bamburg et al.   Current Alzheimer Research

Inflammation in neurodegenerative diseases

(2010) Sandra Amor et al.   IMMUNOLOGY

Memory Impairment in Transgenic Alzheimer Mice Requires Cellular Prion Protein

(2010) D. A. Gimbel et al.   JOURNAL OF NEUROSCIENCE

ADF/cofilin-mediated actin dynamics regulate AMPA receptor trafficking during synaptic plasticity

(2010) Jiaping Gu et al.   NATURE NEUROSCIENCE

ADF/Cofilin: a functional node in cell biology

(2010) Barbara W. Bernstein et al.   TRENDS IN CELL BIOLOGY

The combinations of TNFα-308 and IL-6 -174 or IL-10 -1082 genes polymorphisms suggest an association with susceptibility to sporadic late-onset Alzheimer’s disease

(2009) P. Vural et al.   ACTA NEUROLOGICA SCANDINAVICA

NOX Enzymes in the Central Nervous System: From Signaling to Disease

(2009) Silvia Sorce et al.   ANTIOXIDANTS & REDOX SIGNALING

Isolation and Characterization of Cytoplasmic Cofilin-Actin Rods

(2009) Laurie S. Minamide et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proinflammatory cytokines provoke oxidative damage to actin in neuronal cells mediated by Rac1 and NADPH oxidase

(2009) Brian M. Barth et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Reactive Oxygen Species Regulate a Slingshot-Cofilin Activation Pathway

(2009) Jun-Sub Kim et al.   MOLECULAR BIOLOGY OF THE CELL

Riboflavin kinase couples TNF receptor 1 to NADPH oxidase

(2009) Benjamin Yazdanpanah et al.   NATURE

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers

(2009) Juha Laurén et al.   NATURE

Oxidant-induced apoptosis is mediated by oxidation of the actin-regulatory protein cofilin

(2009) Fábio Klamt et al.   NATURE CELL BIOLOGY

Chronophin Mediates an ATP-Sensing Mechanism for Cofilin Dephosphorylation and Neuronal Cofilin-Actin Rod Formation

(2008) Timothy Y. Huang et al.   DEVELOPMENTAL CELL

SynGAP Regulates Steady-State and Activity-Dependent Phosphorylation of Cofilin

(2008) H. J. Carlisle et al.   JOURNAL OF NEUROSCIENCE

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE

NOX enzymes as novel targets for drug development

(2008) J. David Lambeth et al.   Seminars in Immunopathology