Mitochondrial dysfunction and calcium deregulation by the RanBP9-cofilin pathway

Cooperative role of RanBP9 and P73 in mitochondria-mediated apoptosis

(2013) T Liu et al.   Cell Death & Disease

RanBP9 aggravates synaptic damage in the mouse brain and is inversely correlated to spinophilin levels in Alzheimer’s brain synaptosomes

(2013) J P Palavicini et al.   Cell Death & Disease

Pivotal role of the RanBP9-cofilin pathway in Aβ-induced apoptosis and neurodegeneration

(2012) J A Woo et al.   CELL DEATH AND DIFFERENTIATION

Role of RanBP9 on amyloidogenic processing of APP and synaptic protein levels in the mouse brain

(2012) Madepalli K. Lakshmana et al.   FASEB JOURNAL

Pivotal role of RanBP9 in integrin-dependent focal adhesion signaling and assembly

(2012) Jung A. Woo et al.   FASEB JOURNAL

Impaired Short-Term Plasticity in Mossy Fiber Synapses Caused by Mitochondrial Dysfunction of Dentate Granule Cells Is the Earliest Synaptic Deficit in a Mouse Model of Alzheimer's Disease

(2012) S. H. Lee et al.   JOURNAL OF NEUROSCIENCE

Amyloid beta impairs mitochondrial anterograde transport and degenerates synapses in Alzheimer's disease neurons

(2011) Marcus J. Calkins et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Endogenous amyloidogenesis in long-term rat hippocampal cell cultures

(2011) Sarah J Bertrand et al.   BMC NEUROSCIENCE

Cofilin Aggregation Blocks Intracellular Trafficking and Induces Synaptic Loss in Hippocampal Neurons

(2011) Joseph Cichon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid beta dimers/trimers potently induce cofilin-actin rods that are inhibited by maintaining cofilin-phosphorylation

(2011) Richard C Davis et al.   Molecular Neurodegeneration

The Interface between Cytoskeletal Aberrations and Mitochondrial Dysfunction in Alzheimer's Disease and Related Disorders

(2011) David E. Kang et al.   Experimental Neurobiology

Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model

(2010) H. Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ADF/Cofilin: a functional node in cell biology

(2010) Barbara W. Bernstein et al.   TRENDS IN CELL BIOLOGY

Mitochondrial translocation of oxidized cofilin induces caspase-independent necrotic-like programmed cell death of T cells

(2010) G H Wabnitz et al.   Cell Death & Disease

Impairment of mitochondrial calcium handling in a mtSOD1 cell culture model of motoneuron disease

(2009) Manoj Jaiswal et al.   BMC NEUROSCIENCE

A fragment of the scaffolding protein RanBP9 is increased in Alzheimer’s disease brains and strongly potentiates amyloid-β peptide generation

(2009) Madepalli K. Lakshmana et al.   FASEB JOURNAL

Novel Role of RanBP9 in BACE1 Processing of Amyloid Precursor Protein and Amyloid β Peptide Generation

(2009) Madepalli K. Lakshmana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The antioxidant Trolox restores mitochondrial membrane potential and Ca2+-stimulated ATP production in human complex I deficiency

(2009) Felix Distelmaier et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Oxidant-induced apoptosis is mediated by oxidation of the actin-regulatory protein cofilin

(2009) Fábio Klamt et al.   NATURE CELL BIOLOGY

Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease

(2009) J. Yao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calcium signaling and neurodegenerative diseases

(2009) Ilya Bezprozvanny   TRENDS IN MOLECULAR MEDICINE

Soluble Beta-Amyloid Leads to Mitochondrial Defects in Amyloid Precursor Protein and Tau Transgenic Mice

(2008) Anne Eckert et al.   Neurodegenerative Diseases