TGFβ Activated Kinase 1 (TAK1) at the Crossroad of B Cell Receptor and Toll-Like Receptor 9 Signaling Pathways in Human B Cells

CpG Drives Human Transitional B Cells to Terminal Differentiation and Production of Natural Antibodies

(2014) F. Capolunghi et al.   JOURNAL OF IMMUNOLOGY

Elevated serum B-cell activating factor (BAFF / BLyS) is associated with rising anti-dsDNA antibody levels and flare following B-cell depletion therapy in systemic lupus erythematosus

(2013) Lucy M. Carter et al.   ARTHRITIS AND RHEUMATISM

The BAFF Receptor Transduces Survival Signals by Co-opting the B Cell Receptor Signaling Pathway

(2013) Edina Schweighoffer et al.   IMMUNITY

Bruton’s Tyrosine Kinase Mediates the Synergistic Signalling between TLR9 and the B Cell Receptor by Regulating Calcium and Calmodulin

(2013) Elaine F. Kenny et al.   PLoS One

IL-10-producing regulatory B cells (B10 cells) in autoimmune disease

(2013) Ioannis Kalampokis et al.   ARTHRITIS RESEARCH & THERAPY

Mechanism and In Vitro Pharmacology of TAK1 Inhibition by (5Z)-7-Oxozeaenol

(2012) Jiaquan Wu et al.   ACS Chemical Biology

Immune Regulatory Function of B Cells

(2012) Claudia Mauri et al.   Annual Review of Immunology

Ubiquitination in signaling to and activation of IKK

(2012) Zhijian J. Chen   IMMUNOLOGICAL REVIEWS

TLR9-mediated signals rescue B-cells from Fas-induced apoptosis via inactivation of caspases

(2012) Anikó Hancz et al.   IMMUNOLOGY LETTERS

Endogenous antigen tunes the responsiveness of naive B cells but not T cells

(2012) Julie Zikherman et al.   NATURE

Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure

(2012) Takafumi Oka et al.   NATURE

Targeting of TAK1 in inflammatory disorders and cancer

(2012) Hiroaki Sakurai   TRENDS IN PHARMACOLOGICAL SCIENCES

TLR9 Ligand Induces the Generation of CD20+ Plasmablasts and Plasma Cells from CD27+ Memory B-Cells

(2011) Alexandrine Geffroy-Luseau et al.   Frontiers in Immunology

Targeting BAFF in autoimmunity

(2010) Anne Davidson   CURRENT OPINION IN IMMUNOLOGY

Rescue of the mature B cell compartment in BAFF-deficient mice by treatment with recombinant Fc-BAFF

(2010) Lee Kim Swee et al.   IMMUNOLOGY LETTERS

TLR1/2, TLR7, and TLR9 Signals Directly Activate Human Peripheral Blood Naive and Memory B Cell Subsets to Produce Cytokines, Chemokines, and Hematopoietic Growth Factors

(2010) Sudhanshu Agrawal et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Macrophage-derived BAFF induces AID expression through the p38MAPK/CREB and JNK/AP-1 pathways

(2010) Hyun-A Kim et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88

(2010) Bing He et al.   NATURE IMMUNOLOGY

A critical role of TAK1 in B-cell receptor–mediated nuclear factor κB activation

(2009) James Schuman et al.   BLOOD

BAFF-R promotes cell proliferation and survival through interaction with IKKβ and NF-κB/c-Rel in the nucleus of normal and neoplastic B-lymphoid cells

(2009) Lingchen Fu et al.   BLOOD

Comprehending the complex connection between PKCβ, TAK1, and IKK in BCR signaling

(2009) Hisaaki Shinohara et al.   IMMUNOLOGICAL REVIEWS

Activation Profile of Intracellular Mitogen-Activated Protein Kinases in Peripheral Lymphocytes of Patients with Systemic Lupus Erythematosus

(2009) Chun K. Wong et al.   JOURNAL OF CLINICAL IMMUNOLOGY

B Cell Receptor and BAFF Receptor Signaling Regulation of B Cell Homeostasis

(2009) W. N. Khan   JOURNAL OF IMMUNOLOGY

TAK1 activation for cytokine synthesis and proliferation of endometriotic cells

(2009) Fuminori Taniguchi et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Multiparameter Phospho-Flow Analysis of Lymphocytes in Early Rheumatoid Arthritis: Implications for Diagnosis and Monitoring Drug Therapy

(2009) Carole L. Galligan et al.   PLoS One

Key developmental transitions in human germinal center B cells are revealed by differential CD45RB expression

(2008) S. M. Jackson et al.   BLOOD

The BLyS Family: Toward a Molecular Understanding of B Cell Homeostasis

(2008) John F. Treml et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

BAFF activates Akt and Erk through BAFF-R in an IKK1-dependent manner in primary mouse B cells

(2008) K. L. Otipoby et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Does the BAFF dysregulation play a major role in the pathogenesis of systemic lupus erythematosus?

(2007) Aymeric Binard et al.   JOURNAL OF AUTOIMMUNITY