Wise Regulates Bone Deposition through Genetic Interactions with Lrp5

Lrp4 and Wise interplay controls the formation and patterning of mammary and other skin appendage placodes by modulating Wnt signaling

(2013) Y. Ahn et al.   DEVELOPMENT

Bone Overgrowth-associated Mutations in theLRP4Gene Impair Sclerostin Facilitator Function

(2011) Olivier Leupin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lrp5 functions in bone to regulate bone mass

(2011) Yajun Cui et al.   NATURE MEDICINE

Sclerosteosis - An autosomal recessive disorder

(2010) Peter Beighton et al.   CLINICAL GENETICS

Inhibition of Wnt signaling by Wise (Sostdc1) and negative feedback from Shh controls tooth number and patterning

(2010) Y. Ahn et al.   DEVELOPMENT

BMP-2 modulates β-catenin signaling through stimulation ofLrp5expression and inhibition of β-TrCP expression in osteoblasts

(2009) Ming Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Lrp5 Controls Bone Formation by Inhibiting Serotonin Synthesis in the Duodenum

(2008) Vijay K. Yadav et al.   CELL