Targeted Disruption of β-Arrestin 2-Mediated Signaling Pathways by Aptamer Chimeras Leads to Inhibition of Leukemic Cell Growth

A polyvalent aptamer system for targeted drug delivery

(2013) Zhiqing Zhang et al.   BIOMATERIALS

Therapeutic RNA aptamers in clinical trials

(2012) Padma Sundaram et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Chimeric aptamers in cancer cell-targeted drug delivery

(2011) Jagat R. Kanwar et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Activation of the hedgehog pathway in chronic myelogeneous leukemia patients

(2011) Bing Long et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

ARRB1-Mediated Regulation of E2F Target Genes in Nicotine-Induced Growth of Lung Tumors

(2011) Piyali Dasgupta et al.   JNCI-Journal of the National Cancer Institute

Targeting 4-1BB Costimulation to Disseminated Tumor Lesions With Bi-specific Oligonucleotide Aptamers

(2011) Fernando Pastor et al.   MOLECULAR THERAPY

 -Arrestin Deficiency Protects Against Pulmonary Fibrosis in Mice and Prevents Fibroblast Invasion of Extracellular Matrix

(2011) A. K. Lovgren et al.   Science Translational Medicine

Aptamers as therapeutics

(2010) Anthony D. Keefe et al.   NATURE REVIEWS DRUG DISCOVERY

Arrestin Development: Emerging Roles for β-arrestins in Developmental Signaling Pathways

(2009) Jeffrey J. Kovacs et al.   DEVELOPMENTAL CELL

Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer

(2009) Paula J. Bates et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia

(2009) Chen Zhao et al.   NATURE

β-Arrestin links endothelin A receptor to β-catenin signaling to induce ovarian cancer cell invasion and metastasis

(2009) Laura Rosanò et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

 -Arrestin-Mediated Localization of Smoothened to the Primary Cilium

(2008) J. J. Kovacs et al.   SCIENCE